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The map label for this gene is srlE [H]

Identifier: 238892797

GI number: 238892797

Start: 595654

End: 596634

Strand: Reverse

Name: srlE [H]

Synonym: KP1_0605

Alternate gene names: 238892797

Gene position: 596634-595654 (Counterclockwise)

Preceding gene: 238892798

Following gene: 238892796

Centisome position: 11.37

GC content: 62.9

Gene sequence:

>981_bases
ATGAACACGGTGCTTATTCCCCCCGGTCCCGGCGGCTACGGCAAGGGGCTGTGGCTGCCCGTCGCCAGCGGCAAAAAGGT
GCTGTCGCTGACCGGGCGGGAAATCCATCCGGTGGCGATAGAAATCGGCGCGCTCACCGAATCGGAAATCGTCAACGGTT
TTGCCGATATCCCGCCGGATAACGACATCCTGTGCGTGGTGATTAACTGCGCCGGGTCCCTGCGCTGCGGCCTGTATCCG
CAGAAGGGCATCCCGACCATCAACGTGCTGCCTACCTGGCGGGCCGGACCGCTGGCACACTTTATTACCGAGGATAACTA
CGTTTCCGGCGTCACGATGGAACAGCTGGTTCTGGTGGACACCGCCGAAGCGCCGGACAGCGAGCCTGAGATAACACCGG
AGCCTGCACCACGGGTTATCACCACGCCACCACCTCCTCGCGGCACAGAGAAGCTGGTGCACATGGTCGAGCAGACCGGC
ACCGCCGTCGGCCACGTTATCGCCCTGCTGTTCGCCGCCAGCCGTGAGGCGGTGGACGTGTCGCTGCGCAACGTTATCCC
GTTTATGGCCTTTGTCTCGCTGCTGATAGCCCTGGTGCAGGAGACCGCACTCGGCAGCCTGATTGCCCACGCCCTGACGC
CGCTGGCGAACTCGTTGTGGGGGCTGTTGCTGCTGTCTCTCATCTGCGGCATTCCTTTCCTCTCCCCGGTGCTCGGGCCG
GGGGCAGCCATCTCGCAGGTGATTGGCGTGATGATAGGCACCCAGATTGGCGCAGGGGCGATATCCCCGGCCTTCGCCCT
GCCCGCCCTGTTTGCGATCAATGTGCAGGTCGGCTGCGACTTCGTGCCGGTAGGTCTTTCCATGCAGGAGGCAAAGCCGG
AGACCATCGCAAAAGGTGTACCCGCCTTTCTGCTGTCGAGACAACTGACCGGACCGCTGGCCGTCATCATCGGCTGGCTG
TTTTCCCTGGGCTTATTCTGA

Upstream 100 bases:

>100_bases
GCGACCTGAATCCCTGCCATATCGGCGCGGTTCATCTCTCCGGCCCGGTGCCGAACCTGCGAGACCTCCACGGCAATCTG
GTGATTGAGGAGGGACGGCC

Downstream 100 bases:

>100_bases
GGACTCAACGATGAACAAAATCAGAGCCGCCGTGGTCGGCGCAGGTATCTACGGCAAACACCATATGAACGCGTACCGCC
ATAACCCGGACACGGTGCTG

Product: putative glucitol/sorbitol-specific PTS family enzyme IIBC component

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFADIPPDNDILCVVINCAGSLRCGLYP
QKGIPTINVLPTWRAGPLAHFITEDNYVSGVTMEQLVLVDTAEAPDSEPEITPEPAPRVITTPPPPRGTEKLVHMVEQTG
TAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLLLLSLICGIPFLSPVLGP
GAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWL
FSLGLF

Sequences:

>Translated_326_residues
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFADIPPDNDILCVVINCAGSLRCGLYP
QKGIPTINVLPTWRAGPLAHFITEDNYVSGVTMEQLVLVDTAEAPDSEPEITPEPAPRVITTPPPPRGTEKLVHMVEQTG
TAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLLLLSLICGIPFLSPVLGP
GAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWL
FSLGLF
>Mature_326_residues
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFADIPPDNDILCVVINCAGSLRCGLYP
QKGIPTINVLPTWRAGPLAHFITEDNYVSGVTMEQLVLVDTAEAPDSEPEITPEPAPRVITTPPPPRGTEKLVHMVEQTG
TAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLLLLSLICGIPFLSPVLGP
GAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWL
FSLGLF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=323, Percent_Identity=44.2724458204334, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 33985; Mature: 33985

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFADIPPD
CCEEEECCCCCCCCCCEEEECCCCCEEEEECCCEECEEEEEECCCCHHHHHHHHCCCCCC
NDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFITEDNYVSGVTMEQLVLVD
CCEEEEEEECCCCCEECCCCCCCCCEEEEECCCCCCCHHHEECCCCCCCCCCHHHEEEEE
TAEAPDSEPEITPEPAPRVITTPPPPRGTEKLVHMVEQTGTAVGHVIALLFAASREAVDV
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
SLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLLLLSLICGIPFLSPVLGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGV
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCHHHCCCHHHHHCC
PAFLLSRQLTGPLAVIIGWLFSLGLF
HHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFADIPPD
CCEEEECCCCCCCCCCEEEECCCCCEEEEECCCEECEEEEEECCCCHHHHHHHHCCCCCC
NDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFITEDNYVSGVTMEQLVLVD
CCEEEEEEECCCCCEECCCCCCCCCEEEEECCCCCCCHHHEECCCCCCCCCCHHHEEEEE
TAEAPDSEPEITPEPAPRVITTPPPPRGTEKLVHMVEQTGTAVGHVIALLFAASREAVDV
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
SLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLLLLSLICGIPFLSPVLGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGV
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCHHHCCCHHHHHCC
PAFLLSRQLTGPLAVIIGWLFSLGLF
HHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9572925 [H]