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The map label for this gene is treB [H]

Identifier: 238892736

GI number: 238892736

Start: 522370

End: 523788

Strand: Reverse

Name: treB [H]

Synonym: KP1_0531

Alternate gene names: 238892736

Gene position: 523788-522370 (Counterclockwise)

Preceding gene: 238892737

Following gene: 238892735

Centisome position: 9.98

GC content: 61.1

Gene sequence:

>1419_bases
ATGAGCAAAGTAAACCAGCAGGACATCGATAAACTGATCGAACTGGTGGGCGGGCGCGGTAACATCGCCACCGTCAGCCA
CTGTATTACCCGTTTGCGCTTTGTGCTGAACGACCCGGCCATCGCCAGACCAAAAGAGATTGAGCAGCTGCGCATGGTGA
AGGGATGCTTCACTAACGCCGGCCAGTTCCAGGTGGTCATCGGCACCGAGGTGGGCGATTACTACAAGGCCCTGCTGGCG
ACCACCGGCCAGACCTCCGCCGATAAAGAGCAGGTCAAGCAGGCCGCGCGGCAAAATATGAAGTGGCATGAACAGTTAAT
CTCGCACTTCGCCGAGATCTTCTTTCCCCTGCTGCCGGCCCTGATCAGCGGCGGTCTGATCCTCGGTTTCCGCAACGTTA
TCGGCGACCTGCCCATGAGCAATGGCCAGACGCTGGCCCAGATGCACCCGTCGCTGAAAACCATCTATGACTTCCTGTGG
CTGATTGGCGAGGCGATCTTCTTCTATCTGCCGGTGGGGATCTGCTGGTCAGCGGTGAAGAAGATGGGCGGCACGCCGAT
CCTCGGGATCGTCCTTGGCGTCACCCTCGTCTCCCCGCAGCTGATGAACGCCTATCTCCTCGGCCAGCAGGTGCCGGAGG
TGTGGAACTTCGGCCTGTTTACCATTGCCAAAGTCGGCTACCAGGCGCAGGTGATCCCGGCCCTGCTGGCTGGCCTGGCC
TTAGGCTTTATCGAGACGCGCCTCAAGCGCATTGTGCCTGACTACCTCTACCTGGTGATTGTCCCGGTCTGCTCGCTGAT
CCTCGCGGTGTTCCTCGCGCACGCCATTATCGGTCCGTTCGGCCGCCTGATCGGCGACGGCGTGGCCTTCGCGGTACGCC
ATCTGTTAACCGGCAGCTTCGCGCCGATCGGCGCCGCGCTGTTCGGCTTCCTCTACGCGCCGCTGGTGATTACCGGTGTC
CACCAGACCACCCTCGCTATCGATATGCAGATGATCCAGAGCATGGGCGGTACCCCGGTGTGGCCGCTGATTGCGTTGTC
GAATATTGCCCAGGCGTCGGCGGTGGTCGGCATCATCATCGCCAGCCGCAAGCAGAATGAACGTGAAATCTCGGTACCGG
CGGCGATCTCCGCCTATCTCGGGGTCACCGAGCCAGCGATGTACGGTATCAACCTGAAATACCGCTTCCCGATGCTGTGC
GCAATGATTGGCTCTGGCCTCGCCGGCCTGCTGTGCGGCCTGAACGGCGTGCTGGCGAACGGCATCGGCGTCGGCGGCCT
GCCGGGGATCCTCTCCATCCAGCCTACCTACTGGCAGGTGTACGCCATGGCGATGGCTATCGCGGTGGTGGTGCCGATTA
TCCTCACCAGCGTGGTGTATCAGCGCAAGTACCGTCAGGGCACCTTGCAGATTGTCTAA

Upstream 100 bases:

>100_bases
CGGGTTTCGGGAACGTTCCCATTTTGCAAATTAAGCGGAACGGTTAGGATGCCCTCAAGGTAAAAACGGCATCTCTCCCC
TCTGTTTTTGAGGCTTCATC

Downstream 100 bases:

>100_bases
CTTCTTCTTTCGGGGCGCCTTTGGCGCCCCTCGTTGCAGCAGGAAAGTACTATGAATCATCTCCCCCACTGGTGGCAAAA
CGGCGTTATTTATCAAATCT

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSKVNQQDIDKLIELVGGRGNIATVSHCITRLRFVLNDPAIARPKEIEQLRMVKGCFTNAGQFQVVIGTEVGDYYKALLA
TTGQTSADKEQVKQAARQNMKWHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMHPSLKTIYDFLW
LIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQVPEVWNFGLFTIAKVGYQAQVIPALLAGLA
LGFIETRLKRIVPDYLYLVIVPVCSLILAVFLAHAIIGPFGRLIGDGVAFAVRHLLTGSFAPIGAALFGFLYAPLVITGV
HQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVVGIIIASRKQNEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSGLAGLLCGLNGVLANGIGVGGLPGILSIQPTYWQVYAMAMAIAVVVPIILTSVVYQRKYRQGTLQIV

Sequences:

>Translated_472_residues
MSKVNQQDIDKLIELVGGRGNIATVSHCITRLRFVLNDPAIARPKEIEQLRMVKGCFTNAGQFQVVIGTEVGDYYKALLA
TTGQTSADKEQVKQAARQNMKWHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMHPSLKTIYDFLW
LIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQVPEVWNFGLFTIAKVGYQAQVIPALLAGLA
LGFIETRLKRIVPDYLYLVIVPVCSLILAVFLAHAIIGPFGRLIGDGVAFAVRHLLTGSFAPIGAALFGFLYAPLVITGV
HQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVVGIIIASRKQNEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSGLAGLLCGLNGVLANGIGVGGLPGILSIQPTYWQVYAMAMAIAVVVPIILTSVVYQRKYRQGTLQIV
>Mature_471_residues
SKVNQQDIDKLIELVGGRGNIATVSHCITRLRFVLNDPAIARPKEIEQLRMVKGCFTNAGQFQVVIGTEVGDYYKALLAT
TGQTSADKEQVKQAARQNMKWHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMHPSLKTIYDFLWL
IGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQVPEVWNFGLFTIAKVGYQAQVIPALLAGLAL
GFIETRLKRIVPDYLYLVIVPVCSLILAVFLAHAIIGPFGRLIGDGVAFAVRHLLTGSFAPIGAALFGFLYAPLVITGVH
QTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVVGIIIASRKQNEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCA
MIGSGLAGLLCGLNGVLANGIGVGGLPGILSIQPTYWQVYAMAMAIAVVVPIILTSVVYQRKYRQGTLQIV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=472, Percent_Identity=90.4661016949153, Blast_Score=858, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=475, Percent_Identity=25.2631578947368, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788769, Length=424, Percent_Identity=25.9433962264151, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI48994906, Length=459, Percent_Identity=27.2331154684096, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50910; Mature: 50779

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVNQQDIDKLIELVGGRGNIATVSHCITRLRFVLNDPAIARPKEIEQLRMVKGCFTNA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
GQFQVVIGTEVGDYYKALLATTGQTSADKEQVKQAARQNMKWHEQLISHFAEIFFPLLPA
CCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LISGGLILGFRNVIGDLPMSNGQTLAQMHPSLKTIYDFLWLIGEAIFFYLPVGICWSAVK
HHCCCHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGGTPILGIVLGVTLVSPQLMNAYLLGQQVPEVWNFGLFTIAKVGYQAQVIPALLAGLA
HCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
LGFIETRLKRIVPDYLYLVIVPVCSLILAVFLAHAIIGPFGRLIGDGVAFAVRHLLTGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APIGAALFGFLYAPLVITGVHQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVVGIII
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
ASRKQNEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCAMIGSGLAGLLCGLNGVLAN
ECCCCCCCCCCCHHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHC
GIGVGGLPGILSIQPTYWQVYAMAMAIAVVVPIILTSVVYQRKYRQGTLQIV
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure 
SKVNQQDIDKLIELVGGRGNIATVSHCITRLRFVLNDPAIARPKEIEQLRMVKGCFTNA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC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CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]