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The map label for this gene is treC [H]

Identifier: 238892735

GI number: 238892735

Start: 520663

End: 522318

Strand: Reverse

Name: treC [H]

Synonym: KP1_0530

Alternate gene names: 238892735

Gene position: 522318-520663 (Counterclockwise)

Preceding gene: 238892736

Following gene: 238892731

Centisome position: 9.95

GC content: 61.47

Gene sequence:

>1656_bases
ATGAATCATCTCCCCCACTGGTGGCAAAACGGCGTTATTTATCAAATCTATCCGAAGAGTTTTCAGGATACCACCGGCAG
CGGTACCGGCGACCTGCGCGGCGTCACCGCCCGCCTCGACTATCTGCAAAAGCTTGGGGTCGACGCCATCTGGCTGACGC
CGTTCTACGTCTCACCGCAGGTAGATAACGGCTACGACGTGGCGAACTACACCGCCATCGACCCCTCCTACGGCACGATG
GCCGACTTTGACGCCCTGGTGGCGGAGGCGAAGGCCCGCGGCATCCGTATCGTGCTGGATATGGTGCTGAACCACACGTC
GACCGAACATGAATGGTTCCGTCAGTCGCTGAATAAGGAGAGTCCCTACCGCCAGTTCTATATCTGGCGCGATGGCGAAC
CGGACGCCCTGCCGAACAACTGGCGCTCTAAATTTGGCGGTAACGCCTGGCAGTGGCACGCCGACAGCGGGCAGTATTAT
CTGCACCTGTTCGCCATTGAGCAGGCGGATCTCAACTGGGAGAATCCGGCGGTGCGCGCCGAGCTGAAAAAGGTCTGCGA
ATTCTGGGCTGACCGCGGCGTCGACGGTCTGCGCCTCGACGTGGTCAACCTGATCTCAAAAGACCAGACCTTTCCCTGCG
ATCTGGACGGGGATGGCCGCCGCTTCTATACCGACGGCCCGCGGGTGCATGAGTTCCTGCAGGAGATGAGCCGCGATGTC
TTCACCCCGCGTAACCTGATGACCGTCGGCGAGATGTCCTCCACCTCGCTGGAGCACTGCCAGCAGTACGCCGCGCTGGA
CGGCCGCGAGCTGTCGATGACCTTTAACTTCCACCATTTAAAGGTCGATTATCCCGGCGGAGAGAAATGGACCCTCGCCC
GCCCGGACTATGTGGCGCTGAAGGCGCTGTTCCGCCACTGGCAGCAGGGAATGCACAATCGGGCGTGGAACGCGCTGTTC
TGGTGTAACCACGATCAGCCGCGCATCGTGTCGCGCTTTGGCGACGAAGGCGAGTACCGGGTGACGGCGGCGAAGATGCT
GGCGATGGTGCTGCACGGCATGCAGGGCACGCCCTATATCTACCAGGGCGAAGAGATCGGCATGACCAATCCGCACTTCA
GCAGCATCAGCGATTACCGTGACGTCGAAAGCCACAATATGTTTATCGAACGTGCGGCGCAGGGGCAAAGCCCGGACGAA
CTGCTGGCGATCCTCGCCAGCAAGTCGCGCGACAACAGCCGCACGCCGATGCCGTGGCACGCCGGCGAGAACGGTGGCTT
CAGCGACGGTGAGCCGTGGATCGGCCTTGGCGATAATTACCAGGAGATCAACGTCGAGGCGGCGCTGGCGGACCCCGATT
CGGTGTTTTATACCTATCAGCAGCTGATTACGCTGCGTAAAACCCTGCCGCTACTGACCTGGGGTGATTACGAGGATCTG
CTGCCGGAGCATCCGTCGCTGTGGTGCTATCGTCGTCAGTGGCAGGGGCAAACGCTGGTAGTCGCCGCTAACCTGAGCCG
CGAGCTGCAGGCCTGGCAGCCCGCTGAGGCCCCGGGCGAGTGGAAGATGATCATCAGCAACTATGCCGAGACCACCCCGC
GCCCGACCGGGCTGACGCTGCGGCCGTTCGAAGCGATATGGTGGCTGCAGGGATAA

Upstream 100 bases:

>100_bases
CGTGGTGTATCAGCGCAAGTACCGTCAGGGCACCTTGCAGATTGTCTAACTTCTTCTTTCGGGGCGCCTTTGGCGCCCCT
CGTTGCAGCAGGAAAGTACT

Downstream 100 bases:

>100_bases
CGCTTTTCCCCGGTGGCGCAACGCTCACCGGGGCTACGATTCGTCAGGCTGGAAGTTATGCGCGGTCGGCATCAGCAATC
GCAGCGCTCGCTTGGGGTTG

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MNHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTARLDYLQKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPSYGTM
ADFDALVAEAKARGIRIVLDMVLNHTSTEHEWFRQSLNKESPYRQFYIWRDGEPDALPNNWRSKFGGNAWQWHADSGQYY
LHLFAIEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDQTFPCDLDGDGRRFYTDGPRVHEFLQEMSRDV
FTPRNLMTVGEMSSTSLEHCQQYAALDGRELSMTFNFHHLKVDYPGGEKWTLARPDYVALKALFRHWQQGMHNRAWNALF
WCNHDQPRIVSRFGDEGEYRVTAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFSSISDYRDVESHNMFIERAAQGQSPDE
LLAILASKSRDNSRTPMPWHAGENGGFSDGEPWIGLGDNYQEINVEAALADPDSVFYTYQQLITLRKTLPLLTWGDYEDL
LPEHPSLWCYRRQWQGQTLVVAANLSRELQAWQPAEAPGEWKMIISNYAETTPRPTGLTLRPFEAIWWLQG

Sequences:

>Translated_551_residues
MNHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTARLDYLQKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPSYGTM
ADFDALVAEAKARGIRIVLDMVLNHTSTEHEWFRQSLNKESPYRQFYIWRDGEPDALPNNWRSKFGGNAWQWHADSGQYY
LHLFAIEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDQTFPCDLDGDGRRFYTDGPRVHEFLQEMSRDV
FTPRNLMTVGEMSSTSLEHCQQYAALDGRELSMTFNFHHLKVDYPGGEKWTLARPDYVALKALFRHWQQGMHNRAWNALF
WCNHDQPRIVSRFGDEGEYRVTAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFSSISDYRDVESHNMFIERAAQGQSPDE
LLAILASKSRDNSRTPMPWHAGENGGFSDGEPWIGLGDNYQEINVEAALADPDSVFYTYQQLITLRKTLPLLTWGDYEDL
LPEHPSLWCYRRQWQGQTLVVAANLSRELQAWQPAEAPGEWKMIISNYAETTPRPTGLTLRPFEAIWWLQG
>Mature_551_residues
MNHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTARLDYLQKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPSYGTM
ADFDALVAEAKARGIRIVLDMVLNHTSTEHEWFRQSLNKESPYRQFYIWRDGEPDALPNNWRSKFGGNAWQWHADSGQYY
LHLFAIEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDQTFPCDLDGDGRRFYTDGPRVHEFLQEMSRDV
FTPRNLMTVGEMSSTSLEHCQQYAALDGRELSMTFNFHHLKVDYPGGEKWTLARPDYVALKALFRHWQQGMHNRAWNALF
WCNHDQPRIVSRFGDEGEYRVTAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFSSISDYRDVESHNMFIERAAQGQSPDE
LLAILASKSRDNSRTPMPWHAGENGGFSDGEPWIGLGDNYQEINVEAALADPDSVFYTYQQLITLRKTLPLLTWGDYEDL
LPEHPSLWCYRRQWQGQTLVVAANLSRELQAWQPAEAPGEWKMIISNYAETTPRPTGLTLRPFEAIWWLQG

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=494, Percent_Identity=30.3643724696356, Blast_Score=227, Evalue=3e-59,
Organism=Homo sapiens, GI65506891, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744481, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744479, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744483, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744475, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744477, Length=113, Percent_Identity=34.5132743362832, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790687, Length=550, Percent_Identity=81.8181818181818, Blast_Score=961, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=188, Percent_Identity=30.8510638297872, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789995, Length=134, Percent_Identity=35.0746268656716, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147709, Length=481, Percent_Identity=25.7796257796258, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI32565753, Length=374, Percent_Identity=22.7272727272727, Blast_Score=108, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=36.6319444444444, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=35.9861591695502, Blast_Score=355, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=36.9791666666667, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=36.9791666666667, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=36.9791666666667, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321731, Length=584, Percent_Identity=35.1027397260274, Blast_Score=329, Evalue=9e-91,
Organism=Saccharomyces cerevisiae, GI6319776, Length=584, Percent_Identity=34.9315068493151, Blast_Score=328, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24583745, Length=554, Percent_Identity=35.0180505415162, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=36.6733466933868, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24583749, Length=547, Percent_Identity=34.0036563071298, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24583747, Length=547, Percent_Identity=34.0036563071298, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24586599, Length=578, Percent_Identity=31.3148788927336, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24586597, Length=503, Percent_Identity=35.9840954274354, Blast_Score=270, Evalue=3e-72,
Organism=Drosophila melanogaster, GI45549022, Length=543, Percent_Identity=32.9650092081031, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24586593, Length=500, Percent_Identity=34.4, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24586587, Length=499, Percent_Identity=32.4649298597194, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24586589, Length=540, Percent_Identity=33.1481481481482, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24586591, Length=490, Percent_Identity=33.0612244897959, Blast_Score=245, Evalue=6e-65,
Organism=Drosophila melanogaster, GI281360393, Length=445, Percent_Identity=32.3595505617978, Blast_Score=199, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63385; Mature: 63385

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTARLDYLQKLGVDAIWLTPFYVSPQ
CCCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPSYGTMADFDALVAEAKARGIRIVLDMVLNHTSTEHEWFRQSLNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHCCCC
SPYRQFYIWRDGEPDALPNNWRSKFGGNAWQWHADSGQYYLHLFAIEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDQTFPCDLDGDGRRFYTDGPRVHEFLQEMSRDV
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FTPRNLMTVGEMSSTSLEHCQQYAALDGRELSMTFNFHHLKVDYPGGEKWTLARPDYVAL
CCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KALFRHWQQGMHNRAWNALFWCNHDQPRIVSRFGDEGEYRVTAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFSSISDYRDVESHNMFIERAAQGQSPDELLAILASKSRDNSRTPMPWH
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
AGENGGFSDGEPWIGLGDNYQEINVEAALADPDSVFYTYQQLITLRKTLPLLTWGDYEDL
CCCCCCCCCCCCCEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCHHHH
LPEHPSLWCYRRQWQGQTLVVAANLSRELQAWQPAEAPGEWKMIISNYAETTPRPTGLTL
CCCCCCEEEEEECCCCCEEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
RPFEAIWWLQG
CCCCEEEEECC
>Mature Secondary Structure
MNHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTARLDYLQKLGVDAIWLTPFYVSPQ
CCCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPSYGTMADFDALVAEAKARGIRIVLDMVLNHTSTEHEWFRQSLNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHCCCC
SPYRQFYIWRDGEPDALPNNWRSKFGGNAWQWHADSGQYYLHLFAIEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDQTFPCDLDGDGRRFYTDGPRVHEFLQEMSRDV
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FTPRNLMTVGEMSSTSLEHCQQYAALDGRELSMTFNFHHLKVDYPGGEKWTLARPDYVAL
CCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KALFRHWQQGMHNRAWNALFWCNHDQPRIVSRFGDEGEYRVTAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFSSISDYRDVESHNMFIERAAQGQSPDELLAILASKSRDNSRTPMPWH
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
AGENGGFSDGEPWIGLGDNYQEINVEAALADPDSVFYTYQQLITLRKTLPLLTWGDYEDL
CCCCCCCCCCCCCEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCHHHH
LPEHPSLWCYRRQWQGQTLVVAANLSRELQAWQPAEAPGEWKMIISNYAETTPRPTGLTL
CCCCCCEEEEEECCCCCEEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
RPFEAIWWLQG
CCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]