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The map label for this gene is sugE [H]

Identifier: 238892636

GI number: 238892636

Start: 423636

End: 423953

Strand: Direct

Name: sugE [H]

Synonym: KP1_0420

Alternate gene names: 238892636

Gene position: 423636-423953 (Clockwise)

Preceding gene: 238892635

Following gene: 238892642

Centisome position: 8.07

GC content: 59.43

Gene sequence:

>318_bases
ATGTCCTGGATAGTCTTGTTTATCGCTGGCCTGCTGGAAGTGGTGTGGGCCGTCGGCCTGAAATATACCCATGGCTTTAG
CCGCTTGGTTCCCAGCGTTATCACCATCGTGGCGATGGTGGCCAGCATGGCGCTGCTCTCATGGGCGATGAAAACCCTAC
CGGTAGGTACCGCCTACGCCGTCTGGACCGGGATCGGCGCCGTGGGGGCCGCCGTGACCGGTATTGTGCTGTTAGGGGAA
TCCGCCAGCGCCATGCGTATCGCCAGCCTTGTCTGTATCGTGATTGGCATCATTGGCCTGAAGATCAGCGCGCACTAA

Upstream 100 bases:

>100_bases
CTCTCATTCCGTTGGATATACTCACCACGACTTTTCATCCACCTTACGGGACGACCCGTAAGCGTTTCTCATCCGGGGAC
GGCCCCAGCAAAGGAGCCTT

Downstream 100 bases:

>100_bases
TCATAGCGCTGATTGACCCAGACCAGTTTGCCGACATCAAAGCCCTGTCGGGTGGCAATGTCCAGCATCTGCTGCCTGAC
CTCCGGGGCGATGGTCGGCG

Product: quarternary ammonium compound transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MSWIVLFIAGLLEVVWAVGLKYTHGFSRLVPSVITIVAMVASMALLSWAMKTLPVGTAYAVWTGIGAVGAAVTGIVLLGE
SASAMRIASLVCIVIGIIGLKISAH

Sequences:

>Translated_105_residues
MSWIVLFIAGLLEVVWAVGLKYTHGFSRLVPSVITIVAMVASMALLSWAMKTLPVGTAYAVWTGIGAVGAAVTGIVLLGE
SASAMRIASLVCIVIGIIGLKISAH
>Mature_104_residues
SWIVLFIAGLLEVVWAVGLKYTHGFSRLVPSVITIVAMVASMALLSWAMKTLPVGTAYAVWTGIGAVGAAVTGIVLLGES
ASAMRIASLVCIVIGIIGLKISAH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=82.8571428571429, Blast_Score=171, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10853; Mature: 10722

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIVLFIAGLLEVVWAVGLKYTHGFSRLVPSVITIVAMVASMALLSWAMKTLPVGTAYA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGAVGAAVTGIVLLGESASAMRIASLVCIVIGIIGLKISAH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWIVLFIAGLLEVVWAVGLKYTHGFSRLVPSVITIVAMVASMALLSWAMKTLPVGTAYA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGAVGAAVTGIVLLGESASAMRIASLVCIVIGIIGLKISAH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]