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The map label for this gene is fimC [H]

Identifier: 238892629

GI number: 238892629

Start: 418790

End: 419569

Strand: Reverse

Name: fimC [H]

Synonym: KP1_0411

Alternate gene names: 238892629

Gene position: 419569-418790 (Counterclockwise)

Preceding gene: 238892630

Following gene: 238892628

Centisome position: 7.99

GC content: 47.82

Gene sequence:

>780_bases
GTGTTGCGACCTTTACTATCGATTACACCCTCTAATTTTTCCCTAAAGGGTCCCGCTTCACGGCGGGCCCTTTTTTGCAT
TCAGAGAAAAGCCATGTTCAGGACCTTATTAAATCTCACCGTATCCTGTGCATTACTCCTCAGCAGTATTGCTCATGCCG
GTATTGTCGTTGAATCCACCCGCTACCTCTATAAGGAAGGTGCGCGTGAAATTACCGCGCAAATCGAAAATAAAGATGAT
ATTCCCTATCTGATTAAATCCTGGGTTGAAACGCCTGCAGGGAAAGCGCCTTCGTTTATGGCTACCCCACCGCTTTTTCG
CCTCGAGGGGAAACAACAGAATACGGTTCGTCTGTTTGCCACCGGCAACGTTAATGCGCCGACCGACCGGGAATCCATGT
ACTATTTTAACGTGATGGCGATTCCTCCGGCAGATGATGCCAAAGCGAATAACAATACTATTCAACTGGCGGTTCGTCAC
CGCATGCGTCTGGTCTATCGTCCCAAAACACTTTTCGACCTCTCCCCTAATACGGAAGCGAAAAAGCTCGAATGGCGTAA
GGCCGGCAAAAAGCTGACCATCAAAAATCCGACACCGTTTTTCTTTTATTTCAATAGCATCCAGCTTGGTGGGAAAGAAG
TGAAGCCGGAAGTCAACTCCGTCGCCCCAATGACGACCAAAGAAGTGACGCTAAAAGAAAATATTAATGCCTCCAGCATT
ACCTGGAAAGTGGTCAATGATTATGGCGGAGCAGGGTCGCTCTATTCCTCATCGCTGTAA

Upstream 100 bases:

>100_bases
TCCGAAAGCTACTCTGCAACCAACGGTACTCAGCTGAAGTACACCACTGGTTATGTAAGAACTAACGCCGCGACTCCGGT
TACCGAAGGTCCGGTTAAAG

Downstream 100 bases:

>100_bases
TAAGAAATTTATTTTATCATTATAGGGATGTGTCTATGCCAAATAAGAATAATGGATTATTCAAACTATCCACCGTCTTT
CTCGCAATGCTTCCGGCATT

Product: putative fimbrial biogenesis periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLRPLLSITPSNFSLKGPASRRALFCIQRKAMFRTLLNLTVSCALLLSSIAHAGIVVESTRYLYKEGAREITAQIENKDD
IPYLIKSWVETPAGKAPSFMATPPLFRLEGKQQNTVRLFATGNVNAPTDRESMYYFNVMAIPPADDAKANNNTIQLAVRH
RMRLVYRPKTLFDLSPNTEAKKLEWRKAGKKLTIKNPTPFFFYFNSIQLGGKEVKPEVNSVAPMTTKEVTLKENINASSI
TWKVVNDYGGAGSLYSSSL

Sequences:

>Translated_259_residues
MLRPLLSITPSNFSLKGPASRRALFCIQRKAMFRTLLNLTVSCALLLSSIAHAGIVVESTRYLYKEGAREITAQIENKDD
IPYLIKSWVETPAGKAPSFMATPPLFRLEGKQQNTVRLFATGNVNAPTDRESMYYFNVMAIPPADDAKANNNTIQLAVRH
RMRLVYRPKTLFDLSPNTEAKKLEWRKAGKKLTIKNPTPFFFYFNSIQLGGKEVKPEVNSVAPMTTKEVTLKENINASSI
TWKVVNDYGGAGSLYSSSL
>Mature_259_residues
MLRPLLSITPSNFSLKGPASRRALFCIQRKAMFRTLLNLTVSCALLLSSIAHAGIVVESTRYLYKEGAREITAQIENKDD
IPYLIKSWVETPAGKAPSFMATPPLFRLEGKQQNTVRLFATGNVNAPTDRESMYYFNVMAIPPADDAKANNNTIQLAVRH
RMRLVYRPKTLFDLSPNTEAKKLEWRKAGKKLTIKNPTPFFFYFNSIQLGGKEVKPEVNSVAPMTTKEVTLKENINASSI
TWKVVNDYGGAGSLYSSSL

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=242, Percent_Identity=35.1239669421488, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786333, Length=228, Percent_Identity=33.7719298245614, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789532, Length=218, Percent_Identity=32.5688073394495, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787171, Length=229, Percent_Identity=33.6244541484716, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786743, Length=223, Percent_Identity=33.1838565022422, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788428, Length=227, Percent_Identity=28.1938325991189, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786936, Length=221, Percent_Identity=28.5067873303167, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788677, Length=207, Percent_Identity=28.5024154589372, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082203, Length=218, Percent_Identity=30.2752293577982, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081806, Length=215, Percent_Identity=24.6511627906977, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 28956; Mature: 28956

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPLLSITPSNFSLKGPASRRALFCIQRKAMFRTLLNLTVSCALLLSSIAHAGIVVEST
CCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECH
RYLYKEGAREITAQIENKDDIPYLIKSWVETPAGKAPSFMATPPLFRLEGKQQNTVRLFA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEE
TGNVNAPTDRESMYYFNVMAIPPADDAKANNNTIQLAVRHRMRLVYRPKTLFDLSPNTEA
ECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEEECCEEEEECCCEEEECCCCCCH
KKLEWRKAGKKLTIKNPTPFFFYFNSIQLGGKEVKPEVNSVAPMTTKEVTLKENINASSI
HHHHHHHCCCEEEECCCCCEEEEEEEEEECCEECCCCCCCCCCCCEEEEEEECCCCCCEE
TWKVVNDYGGAGSLYSSSL
EEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLRPLLSITPSNFSLKGPASRRALFCIQRKAMFRTLLNLTVSCALLLSSIAHAGIVVEST
CCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECH
RYLYKEGAREITAQIENKDDIPYLIKSWVETPAGKAPSFMATPPLFRLEGKQQNTVRLFA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEE
TGNVNAPTDRESMYYFNVMAIPPADDAKANNNTIQLAVRHRMRLVYRPKTLFDLSPNTEA
ECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEEECCEEEEECCCEEEECCCCCCH
KKLEWRKAGKKLTIKNPTPFFFYFNSIQLGGKEVKPEVNSVAPMTTKEVTLKENINASSI
HHHHHHHCCCEEEECCCCCEEEEEEEEEECCEECCCCCCCCCCCCEEEEEEECCCCCCEE
TWKVVNDYGGAGSLYSSSL
EEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]