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The map label for this gene is yjcC [H]

Identifier: 238892551

GI number: 238892551

Start: 334672

End: 336276

Strand: Direct

Name: yjcC [H]

Synonym: KP1_0324

Alternate gene names: 238892551

Gene position: 334672-336276 (Clockwise)

Preceding gene: 238892550

Following gene: 238892553

Centisome position: 6.38

GC content: 54.45

Gene sequence:

>1605_bases
ATGGGTGACAGTGCGCCGCATAAGGCGCTAAGACTCATCGGAACAGGTTTGGTTATTTTATTGCCAGTGGTGCTGGCATT
GTGGTTTGCCCAGCTGCGGGCTAAAGCCGAAACCATTGATCAATTACACTCATTTTCGCAGCTGGCGCTGCAAAAAACGG
AAATGGTCATCCGGGAAGCGGATCAGGCTCGGGCTAAAGCCAGCCAGTATCGCGGTGAGTTGTGTTCAGCGGATCACCAG
CGTTATTTACTGCATATTGTGCGCGGCCTGCTGTATGTGGAAGATCTGATCTACGCTAACGGCCAGCGCTTTATCTGTTC
AACGTCCGTTCATCAGCAAACCGGCTGGCGGATGCCGGCGGCTAATTACACCAAAAAGCCGGATGTCGCGATTTACTATT
ACCGGGACACGCCGTTTTATCCGGGCTTTGCCATGAATTATATGCAGAAGGGGCCCTATGTTGTGGTGGTTAATCCCTTC
TCGTACAGCTCGGTGATCGCCAGCGACCGCGATTTAGCCTATGGCGTTTTCGATACCAAAACCAACCTCTTTTTCTCGGT
AAGTAACAATGTCGAGCCCGCGGAACTCCATGCGTTAATTCGCGAAGGCGATACCTTTTTTAATCAGAATGGCCGGGTGT
ATACGATCGCCCGCTCCGCTATTCGCCCCATCGCCGTCATTATGTCCACCTCGCGGGCCAGCTACTATCACAACTTTTGT
GACCAGGCCAGTCTGACGCTGCCGCTGGGGATAATTTGCAGTATTTTACTGGTGCTGGTGTGGTCGCGCACCCGCCGACA
GTATCACTCGCCGCGCAATATGCTGCAGCGGGCTCTGAGCTGCCGCCAGCTGCGCCTGCACTACCAGCCGATTATCGATA
TTAAAAATAACCGCTGCGTTGGGGCGGAAGCGCTGCTGCGCTGGCCTGGGTTTGACGGTCCGGTGATGAACCCGGCGGAG
TTTATTCCGCTGGCGGAAAATGAAGGCATGATTGCCCAGGTCACGGACTACGTGGTGGATGAACTGTTTTATGAAATGGG
TGAGTTTCTGGCCAGCCATCCACAGTTGTATATAGCCATCAATCTCTCTGCGTCGGATTTCCATTCGGCGCGGCTGATTT
CACAGATCAGTGAGAAAGCGCACAGCTACGCGGTCTGTATCGGACAAATCAAAATCGAAGTGACCGAGCGCGGGTTTATC
GACGTACCGAAGACCACGCCGGTGATCCAGGCGTTCCGCGAAGCAGGCTATGAAATTGCCATCGACGATTTCGGCACCGG
CTACTCGAATCTGCATAATCTGCACGCGCTGAACGTCGATATCCTCAAAATCGATAAAACCTTCGTCGATACGCTCACCA
CCAACAACACCAGCCACCTGATTGCTGAACATATCATCGAGATGGCGCGCGGGTTGCGGTTAAAGACGATTGCAGAAGGC
GTGGAGACGCCGGAGCAGGTAAGCTGGCTCTACAAGCGCGGCGTACAGTATTGCCAGGGCTGGCTGTTTGCGAAAGCGAT
GCCGGCGCGGGAGTTTATGCAGTGGTTAGCCAATGCTCCCGCGCCCGCGAACGTGCCTCAGCCGCCGCGTCACGCGGAGA
TCTGA

Upstream 100 bases:

>100_bases
CGTGAGGGCTGTCGGATGTCAGCTGATGTCTATCGCAATCGCGATTGCTAACGTGTTCGGGCTACCTTAATTAAGGCATA
TCGCATGGATGTAAGCGTAA

Downstream 100 bases:

>100_bases
TGGCGATAGTCGCTGGGAGTGCGGTCAAACTCGCGGCGGAACACCCGGGAGAAGGTTTGCTGCGAGACGTAGCCCAGATC
CATGGCGATATCAAAGATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MGDSAPHKALRLIGTGLVILLPVVLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREADQARAKASQYRGELCSADHQ
RYLLHIVRGLLYVEDLIYANGQRFICSTSVHQQTGWRMPAANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPF
SYSSVIASDRDLAYGVFDTKTNLFFSVSNNVEPAELHALIREGDTFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFC
DQASLTLPLGIICSILLVLVWSRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCVGAEALLRWPGFDGPVMNPAE
FIPLAENEGMIAQVTDYVVDELFYEMGEFLASHPQLYIAINLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFI
DVPKTTPVIQAFREAGYEIAIDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEG
VETPEQVSWLYKRGVQYCQGWLFAKAMPAREFMQWLANAPAPANVPQPPRHAEI

Sequences:

>Translated_534_residues
MGDSAPHKALRLIGTGLVILLPVVLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREADQARAKASQYRGELCSADHQ
RYLLHIVRGLLYVEDLIYANGQRFICSTSVHQQTGWRMPAANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPF
SYSSVIASDRDLAYGVFDTKTNLFFSVSNNVEPAELHALIREGDTFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFC
DQASLTLPLGIICSILLVLVWSRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCVGAEALLRWPGFDGPVMNPAE
FIPLAENEGMIAQVTDYVVDELFYEMGEFLASHPQLYIAINLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFI
DVPKTTPVIQAFREAGYEIAIDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEG
VETPEQVSWLYKRGVQYCQGWLFAKAMPAREFMQWLANAPAPANVPQPPRHAEI
>Mature_533_residues
GDSAPHKALRLIGTGLVILLPVVLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREADQARAKASQYRGELCSADHQR
YLLHIVRGLLYVEDLIYANGQRFICSTSVHQQTGWRMPAANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPFS
YSSVIASDRDLAYGVFDTKTNLFFSVSNNVEPAELHALIREGDTFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFCD
QASLTLPLGIICSILLVLVWSRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCVGAEALLRWPGFDGPVMNPAEF
IPLAENEGMIAQVTDYVVDELFYEMGEFLASHPQLYIAINLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFID
VPKTTPVIQAFREAGYEIAIDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEGV
ETPEQVSWLYKRGVQYCQGWLFAKAMPAREFMQWLANAPAPANVPQPPRHAEI

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=521, Percent_Identity=55.278310940499, Blast_Score=594, Evalue=1e-171,
Organism=Escherichia coli, GI87081743, Length=500, Percent_Identity=33.2, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788502, Length=275, Percent_Identity=31.6363636363636, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=34.5098039215686, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081845, Length=541, Percent_Identity=24.3992606284658, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87081921, Length=246, Percent_Identity=34.9593495934959, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1787541, Length=242, Percent_Identity=32.2314049586777, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI226510982, Length=239, Percent_Identity=35.5648535564854, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1788849, Length=237, Percent_Identity=32.9113924050633, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=31.9502074688797, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1787055, Length=256, Percent_Identity=33.203125, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787410, Length=221, Percent_Identity=26.6968325791855, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 60361; Mature: 60230

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDSAPHKALRLIGTGLVILLPVVLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREA
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARAKASQYRGELCSADHQRYLLHIVRGLLYVEDLIYANGQRFICSTSVHQQTGWRMPA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCC
ANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPFSYSSVIASDRDLAYGVFDTK
CCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCHHHHCCCCCCEEEEEECC
TNLFFSVSNNVEPAELHALIREGDTFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFC
CCEEEEECCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHH
DQASLTLPLGIICSILLVLVWSRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEE
GAEALLRWPGFDGPVMNPAEFIPLAENEGMIAQVTDYVVDELFYEMGEFLASHPQLYIAI
CHHHHHCCCCCCCCCCCHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFIDVPKTTPVIQAFREAGYEIA
ECCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCEECCCCCHHHHHHHHCCCEEE
IDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEG
EECCCCCHHHHCCEEEEEEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VETPEQVSWLYKRGVQYCQGWLFAKAMPAREFMQWLANAPAPANVPQPPRHAEI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GDSAPHKALRLIGTGLVILLPVVLALWFAQLRAKAETIDQLHSFSQLALQKTEMVIREA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARAKASQYRGELCSADHQRYLLHIVRGLLYVEDLIYANGQRFICSTSVHQQTGWRMPA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCC
ANYTKKPDVAIYYYRDTPFYPGFAMNYMQKGPYVVVVNPFSYSSVIASDRDLAYGVFDTK
CCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCHHHHCCCCCCEEEEEECC
TNLFFSVSNNVEPAELHALIREGDTFFNQNGRVYTIARSAIRPIAVIMSTSRASYYHNFC
CCEEEEECCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHH
DQASLTLPLGIICSILLVLVWSRTRRQYHSPRNMLQRALSCRQLRLHYQPIIDIKNNRCV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEE
GAEALLRWPGFDGPVMNPAEFIPLAENEGMIAQVTDYVVDELFYEMGEFLASHPQLYIAI
CHHHHHCCCCCCCCCCCHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NLSASDFHSARLISQISEKAHSYAVCIGQIKIEVTERGFIDVPKTTPVIQAFREAGYEIA
ECCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCEECCCCCHHHHHHHHCCCEEE
IDDFGTGYSNLHNLHALNVDILKIDKTFVDTLTTNNTSHLIAEHIIEMARGLRLKTIAEG
EECCCCCHHHHCCEEEEEEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VETPEQVSWLYKRGVQYCQGWLFAKAMPAREFMQWLANAPAPANVPQPPRHAEI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]