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The map label for this gene is dppA [H]

Identifier: 238028293

GI number: 238028293

Start: 3124685

End: 3126343

Strand: Direct

Name: dppA [H]

Synonym: bglu_1g27530

Alternate gene names: 238028293

Gene position: 3124685-3126343 (Clockwise)

Preceding gene: 238028292

Following gene: 238028294

Centisome position: 79.99

GC content: 67.57

Gene sequence:

>1659_bases
ATGCCACTCGATCTGTTCCGCGCCCGCCTCGCGCCAGCGCGAAGCCGGGCCTGCGCCTTGCTGATGCCCCTCGTCGCGGC
CGCCGCGCTCGCCATGACCCTGGCGCCGCCAGTCGCCGGCGCCACGCCGCGCGGCACGCTGGTGTTCTGCAGCGAAGGCA
GCCCGGCCGGCTTCGATCCGGGCCAGCACACCACCAGCACCGACTTCGACGCCAGCACGTACACGGTCTACAACGAACTC
GTGCAGTTTCGCAACGGCACGCTCGATCTCGAACCGGGGCTCGCGACGGGTTGGGAAAGCTCGGCGGACCAGCGCGTCTA
CACGTTCCACCTGCGCCGCGGGGTGAAATTCCAGACCACGCCCTGGTTCCATCCGACACGCGAGTTCAACGCCGACGACG
TCCTGTTCACGTTCAACCGCATGCTCGATCCGCAGTTGTCGTTTCGCCGTGCCTACCCGACGAGCTTCCCGTACTTCAGC
GACCTCGGATTCGACCGCAACATCGTGCGCATCGAAAAGCTCGACGGCAACACGGTGCGCTTCCATCTCAGGACGCCCGA
CGTGATCTTCGCGCGCAACCTGGCGATGAGCTTCGCATCGATCCTGTCGGCCGAGTATGCCGCGCAACTGAGCGCGCGCC
ACCGCGAGGCCGACATCAACCAGTTGCCGGTGGGCACGGGGCCGTTCGTGTTCCGCTCCTACCAGAAGGACTCGCTGATC
CGCTACGACGCGAATCCCGATTACTGGCGGCCCCAGGACGTCCGACTCGCGCATCTGGTATTCGCGATCACCCCCGATCC
AGGCGTGCGCATCCAGAAGCTCGCGAGCGGCGAATGTCAGGTCTCGGTGTTTCCACGTCCGGCGGACCTCGAGGCCGTCA
AGCGCAATCCCGCGCTGAAGCTCGTCTCGGGCGTCGGCTTCAACGTCGGCTTTCTCGCCTACAACACGCAGCACGCGCCG
CTCGATCGCGTCGAGGTGCGCCGCGCGCTCGACATGGCGATCGACAAGCCGGCCATCATCGAGGCGGTGTTCGGAGGCAA
CGCGCGGGTCGCGACCAATCCGATGCCGCCAGCGCAGTGGTCCTACAACCCGGCCTTGAAGGACGCGCCGCATGACCCGG
CCGCCGCGCGCGCGCTGCTCGCGAAGGCGGGCCTCGCGAGCGGCTTCGACCTGACGCTGTGGGCCATGCCGGTGCAGCGC
CCCTACAATCCGAACGCGCGGTTGATGGCGCAGATGATTCAGCAGGATTGGGCGAAGATCGGCGTGCGCGCACGGATCGT
GAGCTACGAATGGGGTGAATACAACCGCCGCGCCAAGCAGAACGGCGAACACGACGCGCTGCTCTACGGCTGGTCGGGCG
ACAACGGCGACCCCGACAACTGGCTCGGCGCGCTGCTCGGCTGCGCCGCCGTCCACGGCGGCAACGTCTCGAAATGGTGC
GATCCGGCGTTCGACGCGCTGATCACCAAGGCGCGCGCCGAGCCCGACCTGAAGGCGCGCACGGCACGCTACGAGCAGGC
GCAGGTGATCTTCAAGCAGCAGGTGCCGTTCACGCCGATCGCGCATTCGATCGTCTCGCTGCCGGCCTCGAAGCGCGTCG
AGGGGCTGGTGTTCTCACCGCTCGGCAGCCACCGGTTCGACGGCGTCTCGCTGCGCTAG

Upstream 100 bases:

>100_bases
GTGCCGAAGCGCCGGACGCGCCGAGAATCGATGCGATCGACAACCGCCGGCCCGGCCGCGCGCCCGATGGCGGCGGGCGC
CGGCCTCATCACACGACACC

Downstream 100 bases:

>100_bases
CACCGCCAAGGCCATGGAGCGGCGCCGGTCCGGCGCATTCCGGACCGGCCGCTACGGCCGGAGCGCACGGCCGGCAGATG
CCGCCGCACGGGGTCGCTCA

Product: family 5 extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MPLDLFRARLAPARSRACALLMPLVAAAALAMTLAPPVAGATPRGTLVFCSEGSPAGFDPGQHTTSTDFDASTYTVYNEL
VQFRNGTLDLEPGLATGWESSADQRVYTFHLRRGVKFQTTPWFHPTREFNADDVLFTFNRMLDPQLSFRRAYPTSFPYFS
DLGFDRNIVRIEKLDGNTVRFHLRTPDVIFARNLAMSFASILSAEYAAQLSARHREADINQLPVGTGPFVFRSYQKDSLI
RYDANPDYWRPQDVRLAHLVFAITPDPGVRIQKLASGECQVSVFPRPADLEAVKRNPALKLVSGVGFNVGFLAYNTQHAP
LDRVEVRRALDMAIDKPAIIEAVFGGNARVATNPMPPAQWSYNPALKDAPHDPAAARALLAKAGLASGFDLTLWAMPVQR
PYNPNARLMAQMIQQDWAKIGVRARIVSYEWGEYNRRAKQNGEHDALLYGWSGDNGDPDNWLGALLGCAAVHGGNVSKWC
DPAFDALITKARAEPDLKARTARYEQAQVIFKQQVPFTPIAHSIVSLPASKRVEGLVFSPLGSHRFDGVSLR

Sequences:

>Translated_552_residues
MPLDLFRARLAPARSRACALLMPLVAAAALAMTLAPPVAGATPRGTLVFCSEGSPAGFDPGQHTTSTDFDASTYTVYNEL
VQFRNGTLDLEPGLATGWESSADQRVYTFHLRRGVKFQTTPWFHPTREFNADDVLFTFNRMLDPQLSFRRAYPTSFPYFS
DLGFDRNIVRIEKLDGNTVRFHLRTPDVIFARNLAMSFASILSAEYAAQLSARHREADINQLPVGTGPFVFRSYQKDSLI
RYDANPDYWRPQDVRLAHLVFAITPDPGVRIQKLASGECQVSVFPRPADLEAVKRNPALKLVSGVGFNVGFLAYNTQHAP
LDRVEVRRALDMAIDKPAIIEAVFGGNARVATNPMPPAQWSYNPALKDAPHDPAAARALLAKAGLASGFDLTLWAMPVQR
PYNPNARLMAQMIQQDWAKIGVRARIVSYEWGEYNRRAKQNGEHDALLYGWSGDNGDPDNWLGALLGCAAVHGGNVSKWC
DPAFDALITKARAEPDLKARTARYEQAQVIFKQQVPFTPIAHSIVSLPASKRVEGLVFSPLGSHRFDGVSLR
>Mature_551_residues
PLDLFRARLAPARSRACALLMPLVAAAALAMTLAPPVAGATPRGTLVFCSEGSPAGFDPGQHTTSTDFDASTYTVYNELV
QFRNGTLDLEPGLATGWESSADQRVYTFHLRRGVKFQTTPWFHPTREFNADDVLFTFNRMLDPQLSFRRAYPTSFPYFSD
LGFDRNIVRIEKLDGNTVRFHLRTPDVIFARNLAMSFASILSAEYAAQLSARHREADINQLPVGTGPFVFRSYQKDSLIR
YDANPDYWRPQDVRLAHLVFAITPDPGVRIQKLASGECQVSVFPRPADLEAVKRNPALKLVSGVGFNVGFLAYNTQHAPL
DRVEVRRALDMAIDKPAIIEAVFGGNARVATNPMPPAQWSYNPALKDAPHDPAAARALLAKAGLASGFDLTLWAMPVQRP
YNPNARLMAQMIQQDWAKIGVRARIVSYEWGEYNRRAKQNGEHDALLYGWSGDNGDPDNWLGALLGCAAVHGGNVSKWCD
PAFDALITKARAEPDLKARTARYEQAQVIFKQQVPFTPIAHSIVSLPASKRVEGLVFSPLGSHRFDGVSLR

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=547, Percent_Identity=48.8117001828154, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1787551, Length=527, Percent_Identity=36.2428842504744, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1787052, Length=480, Percent_Identity=26.6666666666667, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1787762, Length=529, Percent_Identity=26.0869565217391, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI87081878, Length=531, Percent_Identity=24.6704331450094, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789887, Length=506, Percent_Identity=24.1106719367589, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789397, Length=520, Percent_Identity=22.6923076923077, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787495, Length=536, Percent_Identity=22.2014925373134, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61084; Mature: 60953

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDLFRARLAPARSRACALLMPLVAAAALAMTLAPPVAGATPRGTLVFCSEGSPAGFDP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCC
GQHTTSTDFDASTYTVYNELVQFRNGTLDLEPGLATGWESSADQRVYTFHLRRGVKFQTT
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCEECCC
PWFHPTREFNADDVLFTFNRMLDPQLSFRRAYPTSFPYFSDLGFDRNIVRIEKLDGNTVR
CCCCCCCCCCCCCEEEEHHHHCCCCHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEE
FHLRTPDVIFARNLAMSFASILSAEYAAQLSARHREADINQLPVGTGPFVFRSYQKDSLI
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEECCCCCCEE
RYDANPDYWRPQDVRLAHLVFAITPDPGVRIQKLASGECQVSVFPRPADLEAVKRNPALK
EECCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCEE
LVSGVGFNVGFLAYNTQHAPLDRVEVRRALDMAIDKPAIIEAVFGGNARVATNPMPPAQW
EECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCC
SYNPALKDAPHDPAAARALLAKAGLASGFDLTLWAMPVQRPYNPNARLMAQMIQQDWAKI
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GVRARIVSYEWGEYNRRAKQNGEHDALLYGWSGDNGDPDNWLGALLGCAAVHGGNVSKWC
CEEEEEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHC
DPAFDALITKARAEPDLKARTARYEQAQVIFKQQVPFTPIAHSIVSLPASKRVEGLVFSP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEECC
LGSHRFDGVSLR
CCCCCCCCCCCC
>Mature Secondary Structure 
PLDLFRARLAPARSRACALLMPLVAAAALAMTLAPPVAGATPRGTLVFCSEGSPAGFDP
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCC
GQHTTSTDFDASTYTVYNELVQFRNGTLDLEPGLATGWESSADQRVYTFHLRRGVKFQTT
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCEECCC
PWFHPTREFNADDVLFTFNRMLDPQLSFRRAYPTSFPYFSDLGFDRNIVRIEKLDGNTVR
CCCCCCCCCCCCCEEEEHHHHCCCCHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEE
FHLRTPDVIFARNLAMSFASILSAEYAAQLSARHREADINQLPVGTGPFVFRSYQKDSLI
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEECCCCCCEE
RYDANPDYWRPQDVRLAHLVFAITPDPGVRIQKLASGECQVSVFPRPADLEAVKRNPALK
EECCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCEE
LVSGVGFNVGFLAYNTQHAPLDRVEVRRALDMAIDKPAIIEAVFGGNARVATNPMPPAQW
EECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCC
SYNPALKDAPHDPAAARALLAKAGLASGFDLTLWAMPVQRPYNPNARLMAQMIQQDWAKI
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GVRARIVSYEWGEYNRRAKQNGEHDALLYGWSGDNGDPDNWLGALLGCAAVHGGNVSKWC
CEEEEEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHC
DPAFDALITKARAEPDLKARTARYEQAQVIFKQQVPFTPIAHSIVSLPASKRVEGLVFSP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEECC
LGSHRFDGVSLR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]