Click here to switch to the map view.

The map label for this gene is upp [H]

Identifier: 238028182

GI number: 238028182

Start: 2999532

End: 3000182

Strand: Direct

Name: upp [H]

Synonym: bglu_1g26340

Alternate gene names: 238028182

Gene position: 2999532-3000182 (Clockwise)

Preceding gene: 238028179

Following gene: 238028183

Centisome position: 76.78

GC content: 66.97

Gene sequence:

>651_bases
ATGACCCAGGACAGCCGCTTTCCGAACCTTTTCATTCTCGATCACCCGCTGATCCAGCACAAACTCACCCACATGCGCGA
CAAGGACACCTCCACGCGCACGTTCCGCGAGCTGCTGCGCGAGATCACGCTGCTGATGGGCTACGAGATCACGCGCAACC
TGCCGATCACGACGAAACGGGTCGAAACCCCGCTGGTCGAGATCGACGCGCCGGTGATCGCGGGCAAGAAGGTGGCGATC
GTGCCGGTGCTGCGCGCCGGGATCGGCATGTCGGACGGCCTGCTCGACCTGGTGCCGTCGGCGCGCGTCGGCCACATCGG
CGTCTATCGCGCCGACGACCACCGCCCGGTCGAATACCTGGTGCGCCTGCCCGACCTGGAGGACCGCACCTTCATCCTCT
GCGATCCGATGATCGCCACCGGCTATTCGGCGGTCCACGCCGTCGACGTGCTCAAGCGCCGCCAGGTGCCGGGCGAGCGC
CTCCTGTTCCTGGCGCTGGTGGCCGCGCCCGAAGGCATCCAGGTGTTCCAGGACGCGCATCCGGACGTGAAGGTCTACGT
GGCCTCGCTCGATTCGCACCTGAACGACCACGCCTACATCGTGCCGGGCCTCGGCGACGCCGGCGACCGGCTGTTCGGCA
CCAAGAACTGA

Upstream 100 bases:

>100_bases
CGCGCCCCGGCATCTTCGGTAAACTTGCGCCAATGCCGCCGCGCCCCGCAGGCGGCATGCCGAATCCGATGAATCCCTTT
TCCGCCGCCCGTCGCCCCTC

Downstream 100 bases:

>100_bases
GCGCCGGCCACGCGCCGCGCCAGCGGCCGGCGGCGCCGCGCCGCCCGGCCCCGCCTGGCAGCGCGTGAGCGCCGGCACCG
GTCCGGTGCGCGCTTCGTCG

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKVAI
VPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRTFILCDPMIATGYSAVHAVDVLKRRQVPGER
LLFLALVAAPEGIQVFQDAHPDVKVYVASLDSHLNDHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_216_residues
MTQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKVAI
VPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRTFILCDPMIATGYSAVHAVDVLKRRQVPGER
LLFLALVAAPEGIQVFQDAHPDVKVYVASLDSHLNDHAYIVPGLGDAGDRLFGTKN
>Mature_215_residues
TQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKVAIV
PVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRTFILCDPMIATGYSAVHAVDVLKRRQVPGERL
LFLALVAAPEGIQVFQDAHPDVKVYVASLDSHLNDHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=32.6732673267327, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=32.6732673267327, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI87082118, Length=208, Percent_Identity=48.0769230769231, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=25.3588516746411, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321920, Length=211, Percent_Identity=36.4928909952607, Blast_Score=118, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21358379, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24088; Mature: 23957

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKVAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRTFILCDPMIATGYSAVHAVDVLKRRQVPGERLLFLALVAAPEGIQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHHCCCCHHEEHHHHHHCCCCHHHHHCCC
PDVKVYVASLDSHLNDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKVAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRTFILCDPMIATGYSAVHAVDVLKRRQVPGERLLFLALVAAPEGIQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHHCCCCHHEEHHHHHHCCCCHHHHHCCC
PDVKVYVASLDSHLNDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA