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The map label for this gene is tpiA [H]

Identifier: 238028145

GI number: 238028145

Start: 2958154

End: 2958909

Strand: Reverse

Name: tpiA [H]

Synonym: bglu_1g25960

Alternate gene names: 238028145

Gene position: 2958909-2958154 (Counterclockwise)

Preceding gene: 238028146

Following gene: 238028144

Centisome position: 75.74

GC content: 67.99

Gene sequence:

>756_bases
ATGTCGACACAACGAGTGAAGCGGGTAATCGGTAACTGGAAGATGCACGGCCGTCTCAACGGCAATCGCGCGCTGCTGGG
CGAAGTGCTCGATGGGGCGCAGGCCGTGTCGGCCGACGTCGAGATCGGCGTATGCGTGCCGTTTCCGTATCTGGCGCAGG
TCGGCGAATTGCTTGCCGGCAGCCGTGTCGCGAGCGGCGCTCAGGACGTGTCGGCGCACGAGCAAGGCGCGTACACGGGC
GAGGTGGCCGGCGCGATGATCGCCGAGTTCGGCGCGAAATACGTGCTGGTCGGCCACTCCGAGCGCCGTACCTATCACGG
CGAATCGAGCAATCTGGTCGCCGTGAAGGCGCAGCGCGCGCTCGGCGCGGGGCTGACCCCGGTGGTCTGCGTCGGCGAGA
CGCTGGCCGAGCGCGAAGCGGGTTCGACCGAGACGGTGGTCGGCGCGCAGCTCGATGCGGCGCTCGCGCTGCTGTCGGAC
CAAGAGGCGGCGCGCATCGTGGTTGCCTACGAGCCGGTCTGGGCAATCGGCACGGGCAAGAGCGCAAGTTCGGAGCAGGC
ACAGCAGGTGCATGCCTTCCTGCGTTCGCGGCTTGCGGCCAAGGGCGTCGAGCAGGTTTCCGTGCTGTACGGCGGCAGCG
TGAAGCCGGACAATGCGCGCGAACTGTTCGGTCAGCCCGACATCGACGGCGGCCTGATCGGTGGCGCATCGTTGAAGGGC
GGCGATTTCCTGGCGATCTGCCGCGCGGCGCAGTAA

Upstream 100 bases:

>100_bases
AAATCGCGGGTTTGCTTCGTCGGATCCAGGCCCTGGCGGTTCGCGCAGGGGCCGATTGCGAGGCGGTCGCGACGGGATTC
AGTTCGAGATGCGAGAGACG

Downstream 100 bases:

>100_bases
GCGCCGCCGCAGGGGGCGGGCGTTTTTTTGAATCCGGGGCAGCGCGCGGCGCGCGGTTTCCCACTATTCGGGTGAGTGAG
ATGTCTTTTTTGAAAGTCTT

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSTQRVKRVIGNWKMHGRLNGNRALLGEVLDGAQAVSADVEIGVCVPFPYLAQVGELLAGSRVASGAQDVSAHEQGAYTG
EVAGAMIAEFGAKYVLVGHSERRTYHGESSNLVAVKAQRALGAGLTPVVCVGETLAEREAGSTETVVGAQLDAALALLSD
QEAARIVVAYEPVWAIGTGKSASSEQAQQVHAFLRSRLAAKGVEQVSVLYGGSVKPDNARELFGQPDIDGGLIGGASLKG
GDFLAICRAAQ

Sequences:

>Translated_251_residues
MSTQRVKRVIGNWKMHGRLNGNRALLGEVLDGAQAVSADVEIGVCVPFPYLAQVGELLAGSRVASGAQDVSAHEQGAYTG
EVAGAMIAEFGAKYVLVGHSERRTYHGESSNLVAVKAQRALGAGLTPVVCVGETLAEREAGSTETVVGAQLDAALALLSD
QEAARIVVAYEPVWAIGTGKSASSEQAQQVHAFLRSRLAAKGVEQVSVLYGGSVKPDNARELFGQPDIDGGLIGGASLKG
GDFLAICRAAQ
>Mature_250_residues
STQRVKRVIGNWKMHGRLNGNRALLGEVLDGAQAVSADVEIGVCVPFPYLAQVGELLAGSRVASGAQDVSAHEQGAYTGE
VAGAMIAEFGAKYVLVGHSERRTYHGESSNLVAVKAQRALGAGLTPVVCVGETLAEREAGSTETVVGAQLDAALALLSDQ
EAARIVVAYEPVWAIGTGKSASSEQAQQVHAFLRSRLAAKGVEQVSVLYGGSVKPDNARELFGQPDIDGGLIGGASLKGG
DFLAICRAAQ

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=255, Percent_Identity=42.7450980392157, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI226529917, Length=255, Percent_Identity=42.7450980392157, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI1790353, Length=256, Percent_Identity=48.046875, Blast_Score=215, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17536593, Length=246, Percent_Identity=47.5609756097561, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=235, Percent_Identity=42.1276595744681, Blast_Score=176, Evalue=4e-45,
Organism=Drosophila melanogaster, GI28572004, Length=247, Percent_Identity=44.5344129554656, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI28572008, Length=247, Percent_Identity=44.5344129554656, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28572006, Length=247, Percent_Identity=44.5344129554656, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25984; Mature: 25852

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQRVKRVIGNWKMHGRLNGNRALLGEVLDGAQAVSADVEIGVCVPFPYLAQVGELLAG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCHHHCCCCCEEEEEECCHHHHHHHHHHHC
SRVASGAQDVSAHEQGAYTGEVAGAMIAEFGAKYVLVGHSERRTYHGESSNLVAVKAQRA
CHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCEEEEEEHHH
LGAGLTPVVCVGETLAEREAGSTETVVGAQLDAALALLSDQEAARIVVAYEPVWAIGTGK
HCCCCCHHEECCHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCC
SASSEQAQQVHAFLRSRLAAKGVEQVSVLYGGSVKPDNARELFGQPDIDGGLIGGASLKG
CCCHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHCCCCCCCCCEECCCCCCC
GDFLAICRAAQ
CCEEEEEECCC
>Mature Secondary Structure 
STQRVKRVIGNWKMHGRLNGNRALLGEVLDGAQAVSADVEIGVCVPFPYLAQVGELLAG
CHHHHHHHHCCCEEEEEECCCHHHHHHHHCCHHHCCCCCEEEEEECCHHHHHHHHHHHC
SRVASGAQDVSAHEQGAYTGEVAGAMIAEFGAKYVLVGHSERRTYHGESSNLVAVKAQRA
CHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCEEEEEEHHH
LGAGLTPVVCVGETLAEREAGSTETVVGAQLDAALALLSDQEAARIVVAYEPVWAIGTGK
HCCCCCHHEECCHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCC
SASSEQAQQVHAFLRSRLAAKGVEQVSVLYGGSVKPDNARELFGQPDIDGGLIGGASLKG
CCCHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHCCCCCCCCCEECCCCCCC
GDFLAICRAAQ
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]