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The map label for this gene is infC [H]

Identifier: 238027730

GI number: 238027730

Start: 2338476

End: 2338946

Strand: Reverse

Name: infC [H]

Synonym: bglu_1g21510

Alternate gene names: 238027730

Gene position: 2338946-2338476 (Counterclockwise)

Preceding gene: 238027731

Following gene: 238027729

Centisome position: 59.87

GC content: 57.11

Gene sequence:

>471_bases
GTGCGTCTGGTTGGAGTCGATGGAGAGCCCATCGGCATCGTGAAACTCGCCGATGCCTTCCGTAAATCGGAAGAGCTGGA
TGTTGATCTGGTGGAAATCGCGCCGCAGGCCGTTCCCCCCGTTTGCCGTCTGATGGACTACGGCAAGTTCAAGTACCAGG
AATCCAAGAAGCAGCACGAAGCGAAGCTGAAGCAGAAGGTCATCCAGGTCAAGGAAGTGAAGTTCCGCCCGGGTACCGAC
GATGGCGATTACAACGTCAAGCTTCGCAATCTGGTGCGCTTCCTCGAGGAAGGCGACAAGACGAAGATCACGTTGCGTTT
CCGCGGCCGCGAAATGGCTCACCAGGAAATCGGCATGCGCATGCTCGAACGCCTGCGCACCGATCTCGACGAGGTCGGTC
AGGTCGAGCAAATGCCGAAGATGGAAGGGCGCCAGATGATCATGGTGCTCGCTCCCAAGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCCGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCATCGCATCAACG
GTGAAATCAACGCGCCGGAA

Downstream 100 bases:

>100_bases
TCGATGCCGCCGCGTGACGCGCGGCGGCATCGATGCAGTTCGACACCGTGCCCGTCCAGGGCGCGGTGTCAGCCAACGGC
GCCCGCATGCGCGGTGCCGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLVGVDGEPIGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK

Sequences:

>Translated_156_residues
MRLVGVDGEPIGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
>Mature_156_residues
MRLVGVDGEPIGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=69.4267515923567, Blast_Score=206, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18099; Mature: 18099

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGVDGEPIGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHE
CEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
HHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRLVGVDGEPIGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHE
CEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
HHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]