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The map label for this gene is thrS [H]

Identifier: 238027731

GI number: 238027731

Start: 2339050

End: 2340957

Strand: Reverse

Name: thrS [H]

Synonym: bglu_1g21520

Alternate gene names: 238027731

Gene position: 2340957-2339050 (Counterclockwise)

Preceding gene: 238027732

Following gene: 238027730

Centisome position: 59.92

GC content: 63.52

Gene sequence:

>1908_bases
ATGGTTTCGATACGCCTGCCCGACGGCTCAGTTCGACAGTACGAGCATCCGGTGACCGTCGCCGAAGTGGCCGCTTCGAT
CGGCCCCGGTCTCGCCAAGGCCGCGCTCGGCGGCAAGCTCGACGGCGAACTCGTCGACACGTCCGCGCTGATCGATCACG
ACGCGTCGCTTGCGATCGTGACCGACAAGGATGCCGACGGCCTCGACATCATTCGCCACTCGGCGGCGCACCTGCTTGCC
TATGCGGTCAAGGATCTGTATCCGGAGGCGCAGGTGACGATCGGGCCGGTGATCGACAACGGCTTCTACTACGACTTCTC
GTACAGCCGCCCGTTTACGCCGGAAGACCTCGCCAAGATCGAGAAGCGCATGCAGGAGCTCGCGAAGAAGGACGAGCCGG
TGTCGCGGCGCGTCGTCTCGCGCGCCGAGGCGGTGGACTATTTCCGCGGCATCGGCGAGAAGTACAAGGCCGAGATCATC
GAATCGATCCCGTCGAGCGACGAGATCAAGCTCTACTCGCACGGCGGCTTCACCGACCTGTGCCGCGGCCCGCACGTGCC
GTCCACCGGCAAGCTGAAGGTGTTCAAGCTGATGAAGGTGGCCGGCGCTTACTGGCGCGGCGATTCGAAGAACGAGCAGT
TGCAGCGCATCTACGGCACCGCCTGGACCAGGAAGGAAGACCAGGACGCCTATCTGCACATGCTGGAAGAGGCGGAGAAG
CGCGATCACCGCAAGCTCGCCAAGCAGCTCGACCTGTTCCACATGCAGGAGGAATCGCCGGGCATGGTGTTCTGGCACCC
GAAGGGCTGGGCGCTTTGGCAGCAGGTCGAGCAGTATATGCGCCGCCGCGTCAACGAGGCCGGCTATCTCGAGATCAAGA
CGCCGATGATCATGGACCGCTCGCTCTGGGAGGCGTCGGGCCACTGGCAGAACTATCGCGAGAACATGTTTACCACCGAG
TCGGAGAAGCGCGACTACGCGATCAAGCCGATGAATTGCCCGGGCCACGTGCAGGTCTTCAATCATGGCCTGCGCTCGTA
CCGCGACCTGCCGCTGCGCTACGCCGAATTCGGCTCGTGCCATCGCAACGAGGCTTCGGGCGCGCTGCACGGCCTGATGC
GCGTGCGCGGCTTCGTGCAGGACGACGCGCACATCTTCTGCACCGAGGACCAGTTCATCGCCGAGTCGATCGCGTTCAAT
GAACTGGCGATGAGCGTCTACAAGGATTTTGGGTTCGATCAGATCTCGATCAAGCTGTCGCTGCGCCCGGACCAGCGCGC
CGGCACCGACGAAACCTGGGATCGCGCGGAGCAGGGGCTGCGCGACGCGCTGACCGCGTGCGGACTCGCGTGGGAGGAAC
TGCCGGGTGAAGGCGCGTTCTACGGCCCCAAGATCGAGTACCACATCAAGGATGCGCTCGGCCGTTCCTGGCAGTGCGGC
ACGCTGCAACTCGACATGGTGCTGCCGGAGCGCCTCGGCGCCGAGTACGTGGCCGAGGACAACGGCCGCCGCCGGCCGGT
CATGCTGCACCGCGCGATCGTCGGCTCGATGGAGCGTTTTCTTGGCATCCTGATCGAGCACCACGCCGGCGCGATGCCCG
CCTGGCTCGCTCCGGTGCAGGCTATCGTCATGAATATTGCGGAAAACCAGGCCGATTACGCGGGGTCTTTGGCCCAATCG
TTGCAAAAACAAGGGCTTAGGGTGGAGGCCGATTTGCGCAACGAGAAGATTAGCTATAAAATACGCGAACATGCGCTCGA
GAAAGTCCCGTACCTGCTGGTCGTCGGTGACAAGGAGCGTGAAGCACAAACGGTAGCCGTGCGTGCCCGTGGCGGCGTCG
AGCTTGGCGTAATGCCGGTCGAAGCCTTCGTTGAGCACCTGCAGCAGGATCTGCGGGCGTTCAAGTAA

Upstream 100 bases:

>100_bases
TGCTTCAGAATGCGGCCCCTCGAAAGCGGGGCCGCATTTTTTTTGGTCGTTTTCAACGCATTGCCTGCCGCGTCCAGTCG
GCATCACGGAGAGTGCCCTT

Downstream 100 bases:

>100_bases
CCGCCCCGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCATCGCATCA
ACGGTGAAATCAACGCGCCG

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSALIDHDASLAIVTDKDADGLDIIRHSAAHLLA
YAVKDLYPEAQVTIGPVIDNGFYYDFSYSRPFTPEDLAKIEKRMQELAKKDEPVSRRVVSRAEAVDYFRGIGEKYKAEII
ESIPSSDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTRKEDQDAYLHMLEEAEK
RDHRKLAKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNEAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFN
ELAMSVYKDFGFDQISIKLSLRPDQRAGTDETWDRAEQGLRDALTACGLAWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNGRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPVQAIVMNIAENQADYAGSLAQS
LQKQGLRVEADLRNEKISYKIREHALEKVPYLLVVGDKEREAQTVAVRARGGVELGVMPVEAFVEHLQQDLRAFK

Sequences:

>Translated_635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSALIDHDASLAIVTDKDADGLDIIRHSAAHLLA
YAVKDLYPEAQVTIGPVIDNGFYYDFSYSRPFTPEDLAKIEKRMQELAKKDEPVSRRVVSRAEAVDYFRGIGEKYKAEII
ESIPSSDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTRKEDQDAYLHMLEEAEK
RDHRKLAKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNEAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFN
ELAMSVYKDFGFDQISIKLSLRPDQRAGTDETWDRAEQGLRDALTACGLAWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNGRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPVQAIVMNIAENQADYAGSLAQS
LQKQGLRVEADLRNEKISYKIREHALEKVPYLLVVGDKEREAQTVAVRARGGVELGVMPVEAFVEHLQQDLRAFK
>Mature_635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSALIDHDASLAIVTDKDADGLDIIRHSAAHLLA
YAVKDLYPEAQVTIGPVIDNGFYYDFSYSRPFTPEDLAKIEKRMQELAKKDEPVSRRVVSRAEAVDYFRGIGEKYKAEII
ESIPSSDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTRKEDQDAYLHMLEEAEK
RDHRKLAKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNEAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFN
ELAMSVYKDFGFDQISIKLSLRPDQRAGTDETWDRAEQGLRDALTACGLAWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNGRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPVQAIVMNIAENQADYAGSLAQS
LQKQGLRVEADLRNEKISYKIREHALEKVPYLLVVGDKEREAQTVAVRARGGVELGVMPVEAFVEHLQQDLRAFK

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38570111, Length=633, Percent_Identity=39.0205371248025, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI38202255, Length=638, Percent_Identity=38.0877742946708, Blast_Score=449, Evalue=1e-126,
Organism=Homo sapiens, GI20070344, Length=636, Percent_Identity=37.1069182389937, Blast_Score=399, Evalue=1e-111,
Organism=Escherichia coli, GI1788013, Length=634, Percent_Identity=58.8328075709779, Blast_Score=789, Evalue=0.0,
Organism=Escherichia coli, GI1786392, Length=137, Percent_Identity=27.7372262773723, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71984184, Length=633, Percent_Identity=38.3886255924171, Blast_Score=470, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI71984192, Length=633, Percent_Identity=38.3886255924171, Blast_Score=470, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322112, Length=654, Percent_Identity=38.0733944954128, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6322654, Length=397, Percent_Identity=39.5465994962217, Blast_Score=304, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24583842, Length=631, Percent_Identity=39.1442155309033, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI28574141, Length=631, Percent_Identity=39.1442155309033, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24583839, Length=631, Percent_Identity=39.1442155309033, Blast_Score=476, Evalue=1e-134,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 71869; Mature: 71869

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSALIDHDASLAIV
CEEEECCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEECHHHHHCCCCCEEEE
TDKDADGLDIIRHSAAHLLAYAVKDLYPEAQVTIGPVIDNGFYYDFSYSRPFTPEDLAKI
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHH
EKRMQELAKKDEPVSRRVVSRAEAVDYFRGIGEKYKAEIIESIPSSDEIKLYSHGGFTDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHH
CRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTRKEDQDAYLHMLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RDHRKLAKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNEAGYLEIKTPMIMDR
HHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHCH
SLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSC
HHHHCCCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
HRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFNELAMSVYKDFGFDQISIKLS
CCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
LRPDQRAGTDETWDRAEQGLRDALTACGLAWEELPGEGAFYGPKIEYHIKDALGRSWQCG
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCEEEEEEHHHCCCCCCCC
TLQLDMVLPERLGAEYVAEDNGRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPVQ
CEEEEEECHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIVMNIAENQADYAGSLAQSLQKQGLRVEADLRNEKISYKIREHALEKVPYLLVVGDKER
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EAQTVAVRARGGVELGVMPVEAFVEHLQQDLRAFK
CCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSALIDHDASLAIV
CEEEECCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEECHHHHHCCCCCEEEE
TDKDADGLDIIRHSAAHLLAYAVKDLYPEAQVTIGPVIDNGFYYDFSYSRPFTPEDLAKI
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHH
EKRMQELAKKDEPVSRRVVSRAEAVDYFRGIGEKYKAEIIESIPSSDEIKLYSHGGFTDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHH
CRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTRKEDQDAYLHMLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RDHRKLAKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNEAGYLEIKTPMIMDR
HHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHCH
SLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSC
HHHHCCCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
HRNEASGALHGLMRVRGFVQDDAHIFCTEDQFIAESIAFNELAMSVYKDFGFDQISIKLS
CCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
LRPDQRAGTDETWDRAEQGLRDALTACGLAWEELPGEGAFYGPKIEYHIKDALGRSWQCG
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCEEEEEEHHHCCCCCCCC
TLQLDMVLPERLGAEYVAEDNGRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPVQ
CEEEEEECHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIVMNIAENQADYAGSLAQSLQKQGLRVEADLRNEKISYKIREHALEKVPYLLVVGDKER
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EAQTVAVRARGGVELGVMPVEAFVEHLQQDLRAFK
CCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA