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The map label for this gene is rnr [H]

Identifier: 238027544

GI number: 238027544

Start: 2141743

End: 2144208

Strand: Reverse

Name: rnr [H]

Synonym: bglu_1g19620

Alternate gene names: 238027544

Gene position: 2144208-2141743 (Counterclockwise)

Preceding gene: 238027545

Following gene: 238027543

Centisome position: 54.89

GC content: 68.21

Gene sequence:

>2466_bases
TTGAGCAAGTATCCGTATCCCATCCCGAGCCGCGAAGAAATCCTCGGCGTGCTGCGCACGAGCGACGCCCCGCTGGCGGC
GAACGACATAGCCGAAGCACTGTCGATCAAGCGCCAGGAGCGCGAGGGCTTCTTCCGGCGCGTCGCCGCGATGGAGCGCG
ACGGCCAGATCCGGCTCGACAAGCGCGGGCACTATCAACTGACTCATCCGTCGAACTTCGTGGCCGGACGCGTGCAGGGC
CATCGCGACGGCTATGGATTCCTGATCCGCGACGACGGCCAGGACGACCTGTTCCTGCCGAGCGGCGAGATGCAGAAGGT
CATGCACAACGATCGCGTGCTCGCACGGATCGTCGGCTACGACCGCCGCGGCCGCCCGGAAGGACATGTGGTCGAGGTCA
CCGACCGCGCCAACAAGCGCGTGATCGGCCGCCTGCTCAACGAGAACGGTGCGCTGATCTGCGCCCCCGAGGACAAGCGG
ATCGGCCACGACATCCTGATCACCCAGAATCCGAAGAAGGCCAAGGTCGGCCAGGTCGTGGTGGTCGAGCTGACCGAGTT
TCCGAGCCGCCATTCGCAGCCGCTCGGCCGTGTCGAGGAAGTGCTCGGCGACATCGACGATCCGGGCATGGAGATCGAGA
TCGCGGTACGCAAGTACGGTGTACCGCACGAGTTCAGCCCGGCCGCGCTGGCCGCCTCGGCCGCGCTGCCGGACAAGGTG
CGTCCGGTCGACCTGCGCTACCGCGTCGATCTGCGCGACGTGCCGCTCGTCACGATCGACGGCGAGGACGCGCGCGACTT
CGACGACGCGGTCTACTGCGAACCGATGAAGGTCGGCCGTGGCGACGGCTTCCGGCTGATCGTCGCGATCGCCGACGTCT
CGCACTACGTGAAGCCGGGCGAGGCGCTCGACGTCGACGCGCTCGAGCGCAGCACATCGGTCTACTTTCCGCGCCGCGTG
ATCCCGATGCTGCCCGAGAAGCTGTCGAACGGGCTCTGCTCGCTGAACCCGCAGGTGGACCGCTGCGTGCTGGTCTGCGA
CATGGTGGTGACCGCGCGCGGCGAAGTGAAGGCCTATCAGTTCTATCCGGCCGTGATCCACTCGGCGGCGCGCCTGACCT
ATACCGAGGTCGCGGCCGTGCTGGGCAACACCAAGGGGCCGGAGGCCGCGCGCCGTGCCGACCTGCTGCCTCATCTGCAG
GACCTCTACGGCGTCTACAAGGCACTGTTCGCGGCGCGTCAGAAGCGCGGCGCGATCGATTTCGATACCACCGAGACCTA
CATCGTCTGCAACGCGCAGGGCAAGATCGAGCAGATCCTGCCGCGCCAGCGCAACGACGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCCAACGTCTGCGCGGCCGACTTCATGAAGCGCCACAAGCAGTCGGGCCTGTACCGCGTTCACGCCGGT
CCGACGGCCGAGAAGCTCGAGAACCTGCGCTCGTTCCTGCGCGGCATGGGGCTCACGCTCGGCGGCGGCGAGAAGCCTCA
CGCCAGCGACTACGCGGCGCTGATGGCGAAGATCCGCGAGCGGCCCGACGCACAGATGCTGCAGCCGATGCTGCTGCGCT
CGATGCAGCAAGCCGTCTACAGCCCCGACAACATCGGCCACTTCGGTCTGGCCTACGATGCCTACGCGCACTTCACGAGC
CCGATCCGCCGCTATCCCGATCTGCTCACGCACCGCGCGATCTACGCGATCCTGTCCGGCCACCGGTACACGCCGAAGGC
GCCCGACGGCGTGACGCTGAACACGGCGCTCTCGCCGCGGGCCCGCGCGATGCAGAAGGAAGACGGCGAAGCACGCGGCC
GCGCGCGTTCGAACGACGCGATCTGGGAAGAGCTCGGCCTGCACTGCTCGGCCAACGAGCGCCGCGCCGACGAAGCCTCG
CGCGACGTCGAGGCCTGGCTCAAGTGCTATTTCATGCGCGACAAGCTCGGCGAGGAATACGGCGGGATGGTCAACGGCGT
GACGCCGTTCGGGATCTTCGTGCAGCTCGACACGCTGTTCATCGAGGGGCTCGTGCACGTCACCGAACTCGGCTCCGACT
ATTTCCAGTACGACGAGATCAAGAACGAACTGCGCGGCGAGCGTACCGGTATCCGCTACCGGCTGTCGGACCGCGTGCGC
GTGCAGGTCGGCCGCGTCGATCTCGACGCGCGCAAGATCGACTTCCGGCTGGTGCGCGACACGCCCGTGAAGGCGCCGCG
CGGAGCGGTCCCGGCGCCCGCGGAACGCGGCGCGGCGCGCGTGCGTGCGATGCCGGGCGTGACGAGCGAGGACGAGCCGG
CGGTGGGGCGCCGCAAGGCGGCCGTCGGCAGCACCGGCGCGCCCGCCGCCAAGGATGCGCGCGCCGCGCATCCGGCCGCC
AGGAAGAAGGGCGGCACGGCGGCCAAGTCGCCGGCCAAAAAGGCGCGTCCGCGCAAGAAATATTGA

Upstream 100 bases:

>100_bases
TTCGGCGCGGCGTCGGGTGATAGAATGACCCGCAACCTGGCGTCCGATCGTTCGAACCGGACAGGTAGTCCACGCAACGA
GAACAACCATCGACAAGCCC

Downstream 100 bases:

>100_bases
CGCCGCGGCCGGCGCCGCCGTGCGCCGGCCCGGGCGGTCGATGAATCGAAGACGCCGCGTTGTCCGGCTGCGAGGCCGGC
AACGCGGCGCTTCCGTTTGC

Product: Ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFLIRDDGQDDLFLPSGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTDRANKRVIGRLLNENGALICAPEDKR
IGHDILITQNPKKAKVGQVVVVELTEFPSRHSQPLGRVEEVLGDIDDPGMEIEIAVRKYGVPHEFSPAALAASAALPDKV
RPVDLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPMKVGRGDGFRLIVAIADVSHYVKPGEALDVDALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVVTARGEVKAYQFYPAVIHSAARLTYTEVAAVLGNTKGPEAARRADLLPHLQ
DLYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAHKLIEECMLAANVCAADFMKRHKQSGLYRVHAG
PTAEKLENLRSFLRGMGLTLGGGEKPHASDYAALMAKIRERPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTS
PIRRYPDLLTHRAIYAILSGHRYTPKAPDGVTLNTALSPRARAMQKEDGEARGRARSNDAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTPFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVGRVDLDARKIDFRLVRDTPVKAPRGAVPAPAERGAARVRAMPGVTSEDEPAVGRRKAAVGSTGAPAAKDARAAHPAA
RKKGGTAAKSPAKKARPRKKY

Sequences:

>Translated_821_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFLIRDDGQDDLFLPSGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTDRANKRVIGRLLNENGALICAPEDKR
IGHDILITQNPKKAKVGQVVVVELTEFPSRHSQPLGRVEEVLGDIDDPGMEIEIAVRKYGVPHEFSPAALAASAALPDKV
RPVDLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPMKVGRGDGFRLIVAIADVSHYVKPGEALDVDALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVVTARGEVKAYQFYPAVIHSAARLTYTEVAAVLGNTKGPEAARRADLLPHLQ
DLYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAHKLIEECMLAANVCAADFMKRHKQSGLYRVHAG
PTAEKLENLRSFLRGMGLTLGGGEKPHASDYAALMAKIRERPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTS
PIRRYPDLLTHRAIYAILSGHRYTPKAPDGVTLNTALSPRARAMQKEDGEARGRARSNDAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTPFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVGRVDLDARKIDFRLVRDTPVKAPRGAVPAPAERGAARVRAMPGVTSEDEPAVGRRKAAVGSTGAPAAKDARAAHPAA
RKKGGTAAKSPAKKARPRKKY
>Mature_820_residues
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGH
RDGYGFLIRDDGQDDLFLPSGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTDRANKRVIGRLLNENGALICAPEDKRI
GHDILITQNPKKAKVGQVVVVELTEFPSRHSQPLGRVEEVLGDIDDPGMEIEIAVRKYGVPHEFSPAALAASAALPDKVR
PVDLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPMKVGRGDGFRLIVAIADVSHYVKPGEALDVDALERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLVCDMVVTARGEVKAYQFYPAVIHSAARLTYTEVAAVLGNTKGPEAARRADLLPHLQD
LYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAHKLIEECMLAANVCAADFMKRHKQSGLYRVHAGP
TAEKLENLRSFLRGMGLTLGGGEKPHASDYAALMAKIRERPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSP
IRRYPDLLTHRAIYAILSGHRYTPKAPDGVTLNTALSPRARAMQKEDGEARGRARSNDAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVNGVTPFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVGRVDLDARKIDFRLVRDTPVKAPRGAVPAPAERGAARVRAMPGVTSEDEPAVGRRKAAVGSTGAPAAKDARAAHPAAR
KKGGTAAKSPAKKARPRKKY

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=483, Percent_Identity=28.7784679089027, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI190014623, Length=483, Percent_Identity=28.7784679089027, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI134288890, Length=426, Percent_Identity=30.9859154929577, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI19115966, Length=650, Percent_Identity=25.8461538461538, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI219521928, Length=648, Percent_Identity=25.6172839506173, Blast_Score=150, Evalue=4e-36,
Organism=Escherichia coli, GI87082383, Length=751, Percent_Identity=48.4687083888149, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=703, Percent_Identity=26.8847795163585, Blast_Score=191, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI212645896, Length=468, Percent_Identity=29.4871794871795, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17553506, Length=426, Percent_Identity=30.2816901408451, Blast_Score=156, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324552, Length=591, Percent_Identity=26.5651438240271, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24649634, Length=467, Percent_Identity=29.1220556745182, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19922976, Length=451, Percent_Identity=28.3813747228381, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24654597, Length=451, Percent_Identity=28.3813747228381, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24654592, Length=451, Percent_Identity=28.3813747228381, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91203; Mature: 91072

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFLIRDDGQDDLFLPSGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTDRANKRVIGRLLNENGALICAPEDKRIGHDILITQNPKKAKVGQVV
CCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCEE
VVELTEFPSRHSQPLGRVEEVLGDIDDPGMEIEIAVRKYGVPHEFSPAALAASAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCC
RPVDLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPMKVGRGDGFRLIVAIADVSHYVKPG
CCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
EALDVDALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVVTARGEVKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPAVIHSAARLTYTEVAAVLGNTKGPEAARRADLLPHLQDLYGVYKALFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQILPRQRNDAHKLIEECMLAANVCAADFMKRHKQSGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
PTAEKLENLRSFLRGMGLTLGGGEKPHASDYAALMAKIRERPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGHRYTPKAPDGVTLNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHH
ARAMQKEDGEARGRARSNDAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHCCCCHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTPFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVGRVDLDARKIDFRLVRDTPVKAPRGAVPAPAERGAARVRAMPGVTSEDEPAVGRRKA
EEEECEECCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHEEECCCCCCCCCCCCCCHHH
AVGSTGAPAAKDARAAHPAARKKGGTAAKSPAKKARPRKKY
CCCCCCCCCCCCHHHCCCHHHHCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFLIRDDGQDDLFLPSGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTDRANKRVIGRLLNENGALICAPEDKRIGHDILITQNPKKAKVGQVV
CCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCEE
VVELTEFPSRHSQPLGRVEEVLGDIDDPGMEIEIAVRKYGVPHEFSPAALAASAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCC
RPVDLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPMKVGRGDGFRLIVAIADVSHYVKPG
CCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
EALDVDALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVVTARGEVKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPAVIHSAARLTYTEVAAVLGNTKGPEAARRADLLPHLQDLYGVYKALFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQILPRQRNDAHKLIEECMLAANVCAADFMKRHKQSGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
PTAEKLENLRSFLRGMGLTLGGGEKPHASDYAALMAKIRERPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGHRYTPKAPDGVTLNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHH
ARAMQKEDGEARGRARSNDAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHCCCCHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTPFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVGRVDLDARKIDFRLVRDTPVKAPRGAVPAPAERGAARVRAMPGVTSEDEPAVGRRKA
EEEECEECCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHEEECCCCCCCCCCCCCCHHH
AVGSTGAPAAKDARAAHPAARKKGGTAAKSPAKKARPRKKY
CCCCCCCCCCCCHHHCCCHHHHCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]