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The map label for this gene is cysW [H]

Identifier: 238027468

GI number: 238027468

Start: 2054303

End: 2055223

Strand: Reverse

Name: cysW [H]

Synonym: bglu_1g18710

Alternate gene names: 238027468

Gene position: 2055223-2054303 (Counterclockwise)

Preceding gene: 238027469

Following gene: 238027467

Centisome position: 52.61

GC content: 70.36

Gene sequence:

>921_bases
ATGAGCCGCGAATCCACCTCAGCCGTGCTGCCCGCCGGCGCCGCGCCGCGTGCGAAGGCCGCGCGCCGGCGCGATCCCGT
CACCGAATCGCGGCTGGTGCGCTGGGCGCTGACCGGCCTCGCGCTGCTGTTCCTGGCCGGCTTCCTGGTGGTGCCGCTCG
CGGCCGTGTTCGCGCAGGCGCTGGCCAAGGGCATCGGCTTCTACTTCGAGGCGCTCGGCGACCCCGACGCCTGGGCCGCC
ATCGAGCTGACCGTGACGGTGGCCGCGATCGCGGTGCCGCTGAACCTGGTGTTCGGGGTCTGCGCGTCGTGGGCGATCGC
CAAGTTCGAGTTTCGCGGCAAGGCGCTGCTGACCACGCTGATCGACCTGCCGTTCTCGGTGTCGCCGGTCATCTCGGGCC
TCGTCTACGTGCTGCTGTTCGGCGCGCAGGGCTGGCTCGGGCCGTGGCTCGAGGCACATGACGTCCAGATCATCTTCGCC
GTGCCCGGCATCGTGCTGGCGACGATCTTCGTCACCTTCCCGTTCGTCGCGCGCGAGCTGATCCCGCTGATGCAGGCCCA
AGGCAACGACGAGGAGGAAGCCGCGCGCGTGCTGGGCGCCTCCGGCTGGCAGATCTTCCGCCGCGTGACGCTGCCCAACG
TGCGCTGGGGCCTGCTGTACGGCGTGATTCTCTGCAACGCGCGCGCGATGGGCGAGTTCGGCGCGGTATCGGTGGTGTCG
GGCCATATCCGCGGCCAGACCGACACCATGCCGCTGCATGTCGAGATCCTCTACAACGAATACAACTTCTCGGCCGCGTT
CGCGGTGGCCTCGGTGCTGGCCCTGCTCGCGCTCGTCACGCTGGCGCTGAAGCTGCTGGCCGAACGCCGCATGTCGGCCG
AAATCGCCGCGGCGCGCGCTGGCGCCACGGCGCACTCCTGA

Upstream 100 bases:

>100_bases
ATACGCTGCAATGGTGGCTGCAGCGCCGCACCGGCCGCAGCGCGAGCGCTCCGGTGCCGGCCGTGGCCGGCACTGCGGCG
GCCGCCGCCGGAGGTGCGCA

Downstream 100 bases:

>100_bases
TCGAAGAGGCACACCAGATGGGTATCACCGTTCGTAACCTGCACAAGCAATTCGGCGACTTCACGGCGCTCGACGACGTC
TCGCTCGATTTCCCGCCCGG

Product: sulfate ABC transporter inner membrane subunit CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSRESTSAVLPAGAAPRAKAARRRDPVTESRLVRWALTGLALLFLAGFLVVPLAAVFAQALAKGIGFYFEALGDPDAWAA
IELTVTVAAIAVPLNLVFGVCASWAIAKFEFRGKALLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLEAHDVQIIFA
VPGIVLATIFVTFPFVARELIPLMQAQGNDEEEAARVLGASGWQIFRRVTLPNVRWGLLYGVILCNARAMGEFGAVSVVS
GHIRGQTDTMPLHVEILYNEYNFSAAFAVASVLALLALVTLALKLLAERRMSAEIAAARAGATAHS

Sequences:

>Translated_306_residues
MSRESTSAVLPAGAAPRAKAARRRDPVTESRLVRWALTGLALLFLAGFLVVPLAAVFAQALAKGIGFYFEALGDPDAWAA
IELTVTVAAIAVPLNLVFGVCASWAIAKFEFRGKALLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLEAHDVQIIFA
VPGIVLATIFVTFPFVARELIPLMQAQGNDEEEAARVLGASGWQIFRRVTLPNVRWGLLYGVILCNARAMGEFGAVSVVS
GHIRGQTDTMPLHVEILYNEYNFSAAFAVASVLALLALVTLALKLLAERRMSAEIAAARAGATAHS
>Mature_305_residues
SRESTSAVLPAGAAPRAKAARRRDPVTESRLVRWALTGLALLFLAGFLVVPLAAVFAQALAKGIGFYFEALGDPDAWAAI
ELTVTVAAIAVPLNLVFGVCASWAIAKFEFRGKALLTTLIDLPFSVSPVISGLVYVLLFGAQGWLGPWLEAHDVQIIFAV
PGIVLATIFVTFPFVARELIPLMQAQGNDEEEAARVLGASGWQIFRRVTLPNVRWGLLYGVILCNARAMGEFGAVSVVSG
HIRGQTDTMPLHVEILYNEYNFSAAFAVASVLALLALVTLALKLLAERRMSAEIAAARAGATAHS

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=272, Percent_Identity=54.0441176470588, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=36.8932038834951, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786980, Length=231, Percent_Identity=31.6017316017316, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787369, Length=178, Percent_Identity=26.9662921348315, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32658; Mature: 32526

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRESTSAVLPAGAAPRAKAARRRDPVTESRLVRWALTGLALLFLAGFLVVPLAAVFAQA
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKGIGFYFEALGDPDAWAAIELTVTVAAIAVPLNLVFGVCASWAIAKFEFRGKALLTTL
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IDLPFSVSPVISGLVYVLLFGAQGWLGPWLEAHDVQIIFAVPGIVLATIFVTFPFVAREL
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
IPLMQAQGNDEEEAARVLGASGWQIFRRVTLPNVRWGLLYGVILCNARAMGEFGAVSVVS
HHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHC
GHIRGQTDTMPLHVEILYNEYNFSAAFAVASVLALLALVTLALKLLAERRMSAEIAAARA
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GATAHS
CCCCCC
>Mature Secondary Structure 
SRESTSAVLPAGAAPRAKAARRRDPVTESRLVRWALTGLALLFLAGFLVVPLAAVFAQA
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKGIGFYFEALGDPDAWAAIELTVTVAAIAVPLNLVFGVCASWAIAKFEFRGKALLTTL
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IDLPFSVSPVISGLVYVLLFGAQGWLGPWLEAHDVQIIFAVPGIVLATIFVTFPFVAREL
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
IPLMQAQGNDEEEAARVLGASGWQIFRRVTLPNVRWGLLYGVILCNARAMGEFGAVSVVS
HHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHC
GHIRGQTDTMPLHVEILYNEYNFSAAFAVASVLALLALVTLALKLLAERRMSAEIAAARA
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GATAHS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]