Click here to switch to the map view.

The map label for this gene is cbl [H]

Identifier: 238027466

GI number: 238027466

Start: 2052236

End: 2053165

Strand: Reverse

Name: cbl [H]

Synonym: bglu_1g18690

Alternate gene names: 238027466

Gene position: 2053165-2052236 (Counterclockwise)

Preceding gene: 238027467

Following gene: 238027465

Centisome position: 52.56

GC content: 66.13

Gene sequence:

>930_bases
ATGAACTTCCAACAACTGCGCTTCGTTCGGGAAGCGGTACGCCAGAACATGAACCTGACCGAGGTCGCGAACGTGCTCTA
CACGTCGCAGTCGGGCGTTTCGAAGCAGATCAAGGATCTGGAGGACGAACTCGGCGTGGACATCTTCGTGCGCCGCGGCA
AGCGGCTGACCGGCCTGACCGAACCGGGCAAGGCCGTGCATCAGCTGATCGAGCGGATGCTGCTCGACGCCGAGAACCTG
CGCCGCGTGGCGCGCCAGTATGCCGACCAGGACAGCGGCCACCTGGTGGTGGCGACCACCCACACGCAGGCGCGCTACGC
GCTGCCGAAGGTGATCCGCCAGTTCACCGAGGTGTTTCCGAAGGTTCATCTGGCGCTGCGCCAGGGCAGCCCGCAGCAGA
TCGCGCAGATGATCCTGAGCGGCGAGGCCGACGTCGGCATCTCGACCGAGGCGCTCGACCGCTACCCGGACATCGTCACG
TTCCCGTGCTATTCGTGGCATCACACCGTGGTGGTGCCGAAGGATCACCCGCTGGTGGGCCGCGAGAACCTGACGCTCGA
GGAAATCGCCGAGCATCCGATCATCACCTACGACCAGGACTTCACGGGCCGCTCGCACATCGACCAGGCGTTCGCGAAGG
CGGGCGCGGTGCCCGACGTGGTGCTGACGGCGATCGACGCGGACGTGATCAAGACCTATGTCGAGCTCGGCATGGGCATC
GGCGTGGTGGCCGCGATGGCCTACGACGCGCAGCGCGACGCGGGGCTCGTGGCGCTCGACACCCAGCACCTGTTCGAGGC
CAGCACGACGCGGGTGGGCCTGCGCAAGGGCGCGTTCCTGCGCTCCTATGCCTACCGGCTGCTCGAAATGTTCGCACCGC
ACCTGACCGAGGCCGAGATCGCCGCGCAACTGAAGGAAACCGTACTCTGA

Upstream 100 bases:

>100_bases
ACCGCGGTGCCGCGCCATGCGCGCGTGTTTCCGGCGCGCTGAGGCCCGCCTTTCGTCGCCATCGACCCCTATCACGACAA
CGCCCCTGAGAGGCTGACCC

Downstream 100 bases:

>100_bases
GCACGCGGCGCCGCGCCCGCCGAGCGGCGGCGCCGGCGCCATGTCGTTCCGGGCCGCACCGGCACCCGCGTCGTCATCGA
GGCTGCGCACAAGCGTCGCA

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFVRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMILSGEADVGISTEALDRYPDIVT
FPCYSWHHTVVVPKDHPLVGRENLTLEEIAEHPIITYDQDFTGRSHIDQAFAKAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDAGLVALDTQHLFEASTTRVGLRKGAFLRSYAYRLLEMFAPHLTEAEIAAQLKETVL

Sequences:

>Translated_309_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFVRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMILSGEADVGISTEALDRYPDIVT
FPCYSWHHTVVVPKDHPLVGRENLTLEEIAEHPIITYDQDFTGRSHIDQAFAKAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDAGLVALDTQHLFEASTTRVGLRKGAFLRSYAYRLLEMFAPHLTEAEIAAQLKETVL
>Mature_309_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFVRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMILSGEADVGISTEALDRYPDIVT
FPCYSWHHTVVVPKDHPLVGRENLTLEEIAEHPIITYDQDFTGRSHIDQAFAKAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDAGLVALDTQHLFEASTTRVGLRKGAFLRSYAYRLLEMFAPHLTEAEIAAQLKETVL

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=307, Percent_Identity=55.0488599348534, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=50.3378378378378, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=31.1111111111111, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=29.7297297297297, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790399, Length=298, Percent_Identity=26.1744966442953, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788481, Length=258, Percent_Identity=25.968992248062, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=23.6514522821577, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=287, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693105, Length=281, Percent_Identity=21.3523131672598, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082132, Length=134, Percent_Identity=33.5820895522388, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787806, Length=286, Percent_Identity=22.3776223776224, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=224, Percent_Identity=26.7857142857143, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=23.5772357723577, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34491; Mature: 34491

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFVRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHEECCCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILSGEADVGISTEALDRYPDIVTFPCYSWHHTVVVPKDHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEECCCCCCCC
RENLTLEEIAEHPIITYDQDFTGRSHIDQAFAKAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDAQRDAGLVALDTQHLFEASTTRVGLRKGAFLRSYAYRLLEMFAPHLTEAEI
HHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAQLKETVL
HHHHHHHCC
>Mature Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFVRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHEECCCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILSGEADVGISTEALDRYPDIVTFPCYSWHHTVVVPKDHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEECCCCCCCC
RENLTLEEIAEHPIITYDQDFTGRSHIDQAFAKAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDAQRDAGLVALDTQHLFEASTTRVGLRKGAFLRSYAYRLLEMFAPHLTEAEI
HHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAQLKETVL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]