Click here to switch to the map view.

The map label for this gene is alsB [H]

Identifier: 238027465

GI number: 238027465

Start: 2050899

End: 2051855

Strand: Reverse

Name: alsB [H]

Synonym: bglu_1g18680

Alternate gene names: 238027465

Gene position: 2051855-2050899 (Counterclockwise)

Preceding gene: 238027466

Following gene: 238027464

Centisome position: 52.52

GC content: 66.25

Gene sequence:

>957_bases
ATGGATTTCCGTATTCGCCGCCGTGTTCTCGCCGCCGCGCTCGCCGGCGCCGCCATCGCGATCGTGCCGCCCGCCGCGCA
GGCCCAGGCCGCGCACAAGCCGAAGGTCGCGCTGGTGATGAAGTCGCTCGCCAACGAGTTCTTCCTGACCATGGAGAACG
GCGCGAAGGAGTATCAGCAGCACAACCCGGCGCTGTTCGAGCTGGTCACGAACGGCATCAAGGACGAAACCGACACGGCC
AACCAGATCCGCATCGTCGAGCAGATGATCGTGGCCAAGGCCGACGCGATCGTGCTGGCACCGGCCGATTCGAAGGCGCT
GGTGCCGGTGGTGAAGAAGGCGGTGGATGCCGGCATCATCGTCGTCAACATCGACAACCGGCTCGATCCGGACGTGCTGA
AGTCCAAGAACCTCAACGTGCCGTTCGTCGGCCCCGACAACCGCAAGGGCGCGCGCAAGGTCGGCGACTATCTCGCCAAG
CGCCTGAAGGCGGGCGACGAGGTGGGCATCGTCGAGGGCGTGTCGACCACCACCAATGCGCAGCAGCGCACGGCCGGCTA
CCAGGACGCGATGAAGGCGGCGGGCGTGAAGGTGGTGTCGGTCCAGTCGGGCGAGTGGGAGATCGACAAGGGCAACGCGG
TCGCCTCGGCGATGCTCAACGAATATCCGAACCTGAAGGCGCTGCTGTGCGGCAACGACAGCATGGCGATCGGCGCGGTG
TCGGCGGTGCGCGCGGCCGGCAAGGCGGGCAAGGTCTACGTGGTCGGCTACGACGACATCAACGCGATCAAGCCGATGCT
GCAGGACGGCCGCATTCTCGCCACCGCCGACCAGTACGCGGCCAAGCAGGCCGTGTTCGGCATCGACACGGCGCTGAAGG
CGATCGCCGAGCACAAGAAGCAGTCGCAGCTGTCGGGCGTGGTCGAGACGCCGGTCGACCTGATCGTCAAGCAGTAA

Upstream 100 bases:

>100_bases
GTGGCTGTTTTCGCGCCGTGCCGGACACTATCGAGCAAACGTTTGCTCAACATGAAAACGACACCCGGGCAACCGGGACA
GACCAATGAGGAGAAGTTGT

Downstream 100 bases:

>100_bases
GGCGCGCATGGCAACGATCGCAACCACCGGTGCGCCGCTGCTCGAGGTCACGGGCATCGGCAAGACCTATGCGGAACCGG
TGCTGGCCGACGTCTCGCTC

Product: Periplasmic binding protein/LacI transcriptional regulator

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDFRIRRRVLAAALAGAAIAIVPPAAQAQAAHKPKVALVMKSLANEFFLTMENGAKEYQQHNPALFELVTNGIKDETDTA
NQIRIVEQMIVAKADAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKVGDYLAK
RLKAGDEVGIVEGVSTTTNAQQRTAGYQDAMKAAGVKVVSVQSGEWEIDKGNAVASAMLNEYPNLKALLCGNDSMAIGAV
SAVRAAGKAGKVYVVGYDDINAIKPMLQDGRILATADQYAAKQAVFGIDTALKAIAEHKKQSQLSGVVETPVDLIVKQ

Sequences:

>Translated_318_residues
MDFRIRRRVLAAALAGAAIAIVPPAAQAQAAHKPKVALVMKSLANEFFLTMENGAKEYQQHNPALFELVTNGIKDETDTA
NQIRIVEQMIVAKADAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKVGDYLAK
RLKAGDEVGIVEGVSTTTNAQQRTAGYQDAMKAAGVKVVSVQSGEWEIDKGNAVASAMLNEYPNLKALLCGNDSMAIGAV
SAVRAAGKAGKVYVVGYDDINAIKPMLQDGRILATADQYAAKQAVFGIDTALKAIAEHKKQSQLSGVVETPVDLIVKQ
>Mature_318_residues
MDFRIRRRVLAAALAGAAIAIVPPAAQAQAAHKPKVALVMKSLANEFFLTMENGAKEYQQHNPALFELVTNGIKDETDTA
NQIRIVEQMIVAKADAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKVGDYLAK
RLKAGDEVGIVEGVSTTTNAQQRTAGYQDAMKAAGVKVVSVQSGEWEIDKGNAVASAMLNEYPNLKALLCGNDSMAIGAV
SAVRAAGKAGKVYVVGYDDINAIKPMLQDGRILATADQYAAKQAVFGIDTALKAIAEHKKQSQLSGVVETPVDLIVKQ

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=255, Percent_Identity=34.1176470588235, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790192, Length=293, Percent_Identity=30.3754266211604, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790674, Length=205, Percent_Identity=32.1951219512195, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788898, Length=322, Percent_Identity=23.9130434782609, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33721; Mature: 33721

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRIRRRVLAAALAGAAIAIVPPAAQAQAAHKPKVALVMKSLANEFFLTMENGAKEYQQ
CCHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHH
HNPALFELVTNGIKDETDTANQIRIVEQMIVAKADAIVLAPADSKALVPVVKKAVDAGII
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEE
VVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKVGDYLAKRLKAGDEVGIVEGVSTTTNA
EEEECCCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
QQRTAGYQDAMKAAGVKVVSVQSGEWEIDKGNAVASAMLNEYPNLKALLCGNDSMAIGAV
HHHHCCHHHHHHHCCEEEEEEECCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
SAVRAAGKAGKVYVVGYDDINAIKPMLQDGRILATADQYAAKQAVFGIDTALKAIAEHKK
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QSQLSGVVETPVDLIVKQ
HHHHCCHHHCCHHHHCCC
>Mature Secondary Structure
MDFRIRRRVLAAALAGAAIAIVPPAAQAQAAHKPKVALVMKSLANEFFLTMENGAKEYQQ
CCHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHH
HNPALFELVTNGIKDETDTANQIRIVEQMIVAKADAIVLAPADSKALVPVVKKAVDAGII
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEE
VVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKVGDYLAKRLKAGDEVGIVEGVSTTTNA
EEEECCCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
QQRTAGYQDAMKAAGVKVVSVQSGEWEIDKGNAVASAMLNEYPNLKALLCGNDSMAIGAV
HHHHCCHHHHHHHCCEEEEEEECCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
SAVRAAGKAGKVYVVGYDDINAIKPMLQDGRILATADQYAAKQAVFGIDTALKAIAEHKK
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QSQLSGVVETPVDLIVKQ
HHHHCCHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]