Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 238027461

GI number: 238027461

Start: 2046280

End: 2047173

Strand: Reverse

Name: rbsK [H]

Synonym: bglu_1g18640

Alternate gene names: 238027461

Gene position: 2047173-2046280 (Counterclockwise)

Preceding gene: 339905967

Following gene: 238027460

Centisome position: 52.4

GC content: 74.94

Gene sequence:

>894_bases
GTGGTCGGCAGCCTGAACATGGATCTGGTGGTGCGGGCGCCGCGCCTGCCGAAGCCGGGCGAGACGCTGAGCGGCCATGG
CTACGCCCAGGCCGCGGGCGGCAAGGGCGGCAACCAGGCGGTGGCCGCCGCGCGGCTCGGCGCGCGGGTGGCGATGCTCG
GACGCCTCGGCGACGACGCCAACGGCGCCGCGCTGCGCGCCGCGCTCGAAGCCGAGCAAATCGACTGCGCGGCGCTCGCG
ACCAGCGCCGGCGTGCCGACCGGCGTGGCGCTGATCGTGGTGGACGACGCGAGCCAGAACGCGATCGTGATCGTCGCCGG
CGGCAACGGGCTGGTGACGCCGGAGGACGTGGCCGCCCACGACGCGATGATCGCGGCGGCCGACGTGCTGGTCTGTCAGC
TCGAGACCCCGCTGCCGGCCGTGCGCGCCGCGCTGGAGGCGGGGCGCCGCCACGCATGCAGCGTCGTGCTGAATCCGGCG
CCGGCGCTCGCGCCGCTGCCGGACGGCTGGCTGCCGCTGGTCGACTGGCTGATCCCGAACGAGATCGAGGCGGCCGCGCT
GACGGGCGTCGCGATCGCGACGCCGGCCGATGCGGAACTGGCCGCACGGCAGCTCGCGCAAGCCGGCGCGCGCAACGTGA
TCGTCACGCTCGGCGGGCAGGGCGTGGTGGCCCGGCAAGCCGACGGCAGCACGCGCCATTATCCGGCCCCGAAGGTGGAG
GCGGTCGATACGACCGCGGCCGGCGACACCTTCATCGGCGGCTTCGCGGCGCGGCTCGCGGCCGGCGAGACGCCCGACGA
GGCGATCCGCTTCGCGCTACGCGCGGCCGCATTGTCCGTGACGCGGGCCGGTGCGCAACCTTCTATTCCGACCCTACAAG
AGCTCTCCAAGTAG

Upstream 100 bases:

>100_bases
AATCGACCGCGGCCTACAAAGGCGAAGCCGGCCTCACGCCGGCCGTGCGCGCATGAGCGCCGGCGCGCGGGGCGGCCGGC
GGCCGGGCGGGCGGGTTGCC

Downstream 100 bases:

>100_bases
GCGCCGTGCGCGCCTGCGGGCAGCGGCGGTTCTTCGAATCCGGCTTCGCGCCGGATTCTTTCGTTTGGGGATGGCGTTCA
TCGGGCCGGACGCGTCGGGG

Product: Ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVGSLNMDLVVRAPRLPKPGETLSGHGYAQAAGGKGGNQAVAAARLGARVAMLGRLGDDANGAALRAALEAEQIDCAALA
TSAGVPTGVALIVVDDASQNAIVIVAGGNGLVTPEDVAAHDAMIAAADVLVCQLETPLPAVRAALEAGRRHACSVVLNPA
PALAPLPDGWLPLVDWLIPNEIEAAALTGVAIATPADAELAARQLAQAGARNVIVTLGGQGVVARQADGSTRHYPAPKVE
AVDTTAAGDTFIGGFAARLAAGETPDEAIRFALRAAALSVTRAGAQPSIPTLQELSK

Sequences:

>Translated_297_residues
MVGSLNMDLVVRAPRLPKPGETLSGHGYAQAAGGKGGNQAVAAARLGARVAMLGRLGDDANGAALRAALEAEQIDCAALA
TSAGVPTGVALIVVDDASQNAIVIVAGGNGLVTPEDVAAHDAMIAAADVLVCQLETPLPAVRAALEAGRRHACSVVLNPA
PALAPLPDGWLPLVDWLIPNEIEAAALTGVAIATPADAELAARQLAQAGARNVIVTLGGQGVVARQADGSTRHYPAPKVE
AVDTTAAGDTFIGGFAARLAAGETPDEAIRFALRAAALSVTRAGAQPSIPTLQELSK
>Mature_297_residues
MVGSLNMDLVVRAPRLPKPGETLSGHGYAQAAGGKGGNQAVAAARLGARVAMLGRLGDDANGAALRAALEAEQIDCAALA
TSAGVPTGVALIVVDDASQNAIVIVAGGNGLVTPEDVAAHDAMIAAADVLVCQLETPLPAVRAALEAGRRHACSVVLNPA
PALAPLPDGWLPLVDWLIPNEIEAAALTGVAIATPADAELAARQLAQAGARNVIVTLGGQGVVARQADGSTRHYPAPKVE
AVDTTAAGDTFIGGFAARLAAGETPDEAIRFALRAAALSVTRAGAQPSIPTLQELSK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=42.1404682274247, Blast_Score=195, Evalue=4e-50,
Organism=Escherichia coli, GI1790193, Length=295, Percent_Identity=45.0847457627119, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87081971, Length=296, Percent_Identity=27.3648648648649, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082343, Length=295, Percent_Identity=29.8305084745763, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788491, Length=251, Percent_Identity=24.3027888446215, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=39.9328859060403, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=31.4024390243902, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20128807, Length=298, Percent_Identity=42.6174496644295, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24583886, Length=296, Percent_Identity=34.1216216216216, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 29713; Mature: 29713

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSLNMDLVVRAPRLPKPGETLSGHGYAQAAGGKGGNQAVAAARLGARVAMLGRLGDDA
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHEEHHHCCCCC
NGAALRAALEAEQIDCAALATSAGVPTGVALIVVDDASQNAIVIVAGGNGLVTPEDVAAH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHH
DAMIAAADVLVCQLETPLPAVRAALEAGRRHACSVVLNPAPALAPLPDGWLPLVDWLIPN
HHHHHHHEEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCC
EIEAAALTGVAIATPADAELAARQLAQAGARNVIVTLGGQGVVARQADGSTRHYPAPKVE
CCCHHHHCCEEEECCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCE
AVDTTAAGDTFIGGFAARLAAGETPDEAIRFALRAAALSVTRAGAQPSIPTLQELSK
EEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCC
>Mature Secondary Structure
MVGSLNMDLVVRAPRLPKPGETLSGHGYAQAAGGKGGNQAVAAARLGARVAMLGRLGDDA
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHEEHHHCCCCC
NGAALRAALEAEQIDCAALATSAGVPTGVALIVVDDASQNAIVIVAGGNGLVTPEDVAAH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHH
DAMIAAADVLVCQLETPLPAVRAALEAGRRHACSVVLNPAPALAPLPDGWLPLVDWLIPN
HHHHHHHEEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCC
EIEAAALTGVAIATPADAELAARQLAQAGARNVIVTLGGQGVVARQADGSTRHYPAPKVE
CCCHHHHCCEEEECCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCE
AVDTTAAGDTFIGGFAARLAAGETPDEAIRFALRAAALSVTRAGAQPSIPTLQELSK
EEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]