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The map label for this gene is yycR [H]

Identifier: 238027128

GI number: 238027128

Start: 1669620

End: 1670756

Strand: Reverse

Name: yycR [H]

Synonym: bglu_1g15080

Alternate gene names: 238027128

Gene position: 1670756-1669620 (Counterclockwise)

Preceding gene: 238027132

Following gene: 238027127

Centisome position: 42.77

GC content: 68.16

Gene sequence:

>1137_bases
ATGAAAGCACTGGTCTACCAAGGTCCCAAGCAGGTCGAAATCCTCGACATGCCCGATGCGCGCATCGAAAAACCCACCGA
CGTGCTGGTCAAGATCACCACCACCAACATCTGCGGATCGGATCTGCACATGTACGAAGGCAGGACCAACATGGAACCGG
GCCGCATCCTCGGCCACGAGAACCTGGGCGTGGTGGTGGAGGCCGGCCGCGGCGTCGAGCGCATCAAGGTGGGCGACCGC
GTCTGCCTGCCGTTCAACATCGGCTGCGGCTTCTGCAAGAACTGCGAGCGCGGGCTGACCGGCTTTTGCCTGACGGCAAA
CCCCGGCACCGCCGGGGCCGCTTACGGCTTCGCCGGCATGGGCCCTTACAGCGGCGGCCAGGCGGAGCTGCTGCGCGTGC
CGTTCGGCGACTTCAACTGCCTGTTGCTGCCGCCCGATGCCGAGGAAAAGGAAAACGACTACGTGATGCTCTCGGACATC
TTTCCGACCGGCTATCACGCGACGCAGCTGGCGGGCCTGGAGGCCGGCGACAGCGTGGTGATCTACGGCGCCGGCCCGGT
CGGGCTGATGGCGGCCATGTCGGCGCAACTGCGCGGCGCGAGCCGGATCATGGTGGTGGACACCCATGCCGACCGGCTCG
CGCTGGCGGAACGGCTCGGCGCGATCGCGATCGACGACTCGGACGGCGGTGCCGTGGAGCGCGTGCTCGAACTGACCGGC
GGCGAAGGCGCCGACCGCGGCTGCGAATGCGTGGGCTACCAGTGCAGCTGCCACGGCCGCGAGGTCCCGCACGCCACCAT
GAACGCGCTCGTGAAATCGGTACGGCCCACCGGCGGCATCGGCGTGGTGGGGGTGTTCGTCGCCGAGGACCCTCATTCAC
CGGACGCGCTGGCGCGCGAGGGCAAGCTCGCTTTCGACTTCGGCTCGTTCTGGATGAAGGGGCAGCGCATCGCCACCGGT
CAGGCGAACGTCAAGGCCTACAACCGCAAGCTGCGCGACCTGATCGCGGCCGGGCGCGCCCGGCCTTCGCAGATCGTCTC
GCACGAGCTGCCGCTGACGCGCGCGCCCGAAGGCTACCGGCACTTCGATGCGCGCGACGAAGGCTGGACCAAGGTGGTGT
TGAAGGCGGCCGCCTAG

Upstream 100 bases:

>100_bases
GGCCCGGCTGCGATGCCCGTTTCGCGGCATGCACCGTGCTAGGTGGACACGTACGGCGCCCACCGGGCGGCCGCCCTCTT
TCCCCTTTTCCGGAGTCGTG

Downstream 100 bases:

>100_bases
CGCATCCGGGCGCGCGCTGCCGGCGCATCGCCGAGCCGGCGCGCGCGGCACGGCGCTTGCTGAAAACGGGGATCCGCGGG
CCTGCAGGCCCGTCGTCCCA

Product: putative glutathione-independent formaldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKALVYQGPKQVEILDMPDARIEKPTDVLVKITTTNICGSDLHMYEGRTNMEPGRILGHENLGVVVEAGRGVERIKVGDR
VCLPFNIGCGFCKNCERGLTGFCLTANPGTAGAAYGFAGMGPYSGGQAELLRVPFGDFNCLLLPPDAEEKENDYVMLSDI
FPTGYHATQLAGLEAGDSVVIYGAGPVGLMAAMSAQLRGASRIMVVDTHADRLALAERLGAIAIDDSDGGAVERVLELTG
GEGADRGCECVGYQCSCHGREVPHATMNALVKSVRPTGGIGVVGVFVAEDPHSPDALAREGKLAFDFGSFWMKGQRIATG
QANVKAYNRKLRDLIAAGRARPSQIVSHELPLTRAPEGYRHFDARDEGWTKVVLKAAA

Sequences:

>Translated_378_residues
MKALVYQGPKQVEILDMPDARIEKPTDVLVKITTTNICGSDLHMYEGRTNMEPGRILGHENLGVVVEAGRGVERIKVGDR
VCLPFNIGCGFCKNCERGLTGFCLTANPGTAGAAYGFAGMGPYSGGQAELLRVPFGDFNCLLLPPDAEEKENDYVMLSDI
FPTGYHATQLAGLEAGDSVVIYGAGPVGLMAAMSAQLRGASRIMVVDTHADRLALAERLGAIAIDDSDGGAVERVLELTG
GEGADRGCECVGYQCSCHGREVPHATMNALVKSVRPTGGIGVVGVFVAEDPHSPDALAREGKLAFDFGSFWMKGQRIATG
QANVKAYNRKLRDLIAAGRARPSQIVSHELPLTRAPEGYRHFDARDEGWTKVVLKAAA
>Mature_378_residues
MKALVYQGPKQVEILDMPDARIEKPTDVLVKITTTNICGSDLHMYEGRTNMEPGRILGHENLGVVVEAGRGVERIKVGDR
VCLPFNIGCGFCKNCERGLTGFCLTANPGTAGAAYGFAGMGPYSGGQAELLRVPFGDFNCLLLPPDAEEKENDYVMLSDI
FPTGYHATQLAGLEAGDSVVIYGAGPVGLMAAMSAQLRGASRIMVVDTHADRLALAERLGAIAIDDSDGGAVERVLELTG
GEGADRGCECVGYQCSCHGREVPHATMNALVKSVRPTGGIGVVGVFVAEDPHSPDALAREGKLAFDFGSFWMKGQRIATG
QANVKAYNRKLRDLIAAGRARPSQIVSHELPLTRAPEGYRHFDARDEGWTKVVLKAAA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=372, Percent_Identity=25, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI156523966, Length=210, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4501939, Length=210, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1786825, Length=400, Percent_Identity=36, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI87082125, Length=359, Percent_Identity=30.9192200557103, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788073, Length=341, Percent_Identity=28.1524926686217, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790045, Length=258, Percent_Identity=32.1705426356589, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787863, Length=382, Percent_Identity=24.6073298429319, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI226510992, Length=363, Percent_Identity=25.8953168044077, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788075, Length=391, Percent_Identity=27.8772378516624, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788407, Length=230, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081918, Length=243, Percent_Identity=30.4526748971193, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786552, Length=265, Percent_Identity=29.4339622641509, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790718, Length=215, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=253, Percent_Identity=29.6442687747036, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323099, Length=271, Percent_Identity=32.1033210332103, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319955, Length=341, Percent_Identity=29.6187683284457, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322619, Length=341, Percent_Identity=29.6187683284457, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319258, Length=287, Percent_Identity=28.2229965156794, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319257, Length=307, Percent_Identity=28.9902280130293, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737897, Length=341, Percent_Identity=28.7390029325513, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17137530, Length=238, Percent_Identity=32.3529411764706, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI221457811, Length=378, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550770, Length=378, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551930, Length=378, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR014184
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 40263; Mature: 40263

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVYQGPKQVEILDMPDARIEKPTDVLVKITTTNICGSDLHMYEGRTNMEPGRILGHE
CCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCEEECCC
NLGVVVEAGRGVERIKVGDRVCLPFNIGCGFCKNCERGLTGFCLTANPGTAGAAYGFAGM
CCEEEEECCCCEEEEECCCEEEEEEECCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCC
GPYSGGQAELLRVPFGDFNCLLLPPDAEEKENDYVMLSDIFPTGYHATQLAGLEAGDSVV
CCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHEEECCCCCCEEE
IYGAGPVGLMAAMSAQLRGASRIMVVDTHADRLALAERLGAIAIDDSDGGAVERVLELTG
EECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCEEEEECCCCHHHHHHHHHCC
GEGADRGCECVGYQCSCHGREVPHATMNALVKSVRPTGGIGVVGVFVAEDPHSPDALARE
CCCCCCCCEEECEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHC
GKLAFDFGSFWMKGQRIATGQANVKAYNRKLRDLIAAGRARPSQIVSHELPLTRAPEGYR
CCEEEEEHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCC
HFDARDEGWTKVVLKAAA
CCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKALVYQGPKQVEILDMPDARIEKPTDVLVKITTTNICGSDLHMYEGRTNMEPGRILGHE
CCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCEEECCC
NLGVVVEAGRGVERIKVGDRVCLPFNIGCGFCKNCERGLTGFCLTANPGTAGAAYGFAGM
CCEEEEECCCCEEEEECCCEEEEEEECCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCC
GPYSGGQAELLRVPFGDFNCLLLPPDAEEKENDYVMLSDIFPTGYHATQLAGLEAGDSVV
CCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHEEECCCCCCEEE
IYGAGPVGLMAAMSAQLRGASRIMVVDTHADRLALAERLGAIAIDDSDGGAVERVLELTG
EECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCEEEEECCCCHHHHHHHHHCC
GEGADRGCECVGYQCSCHGREVPHATMNALVKSVRPTGGIGVVGVFVAEDPHSPDALARE
CCCCCCCCEEECEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHC
GKLAFDFGSFWMKGQRIATGQANVKAYNRKLRDLIAAGRARPSQIVSHELPLTRAPEGYR
CCEEEEEHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCC
HFDARDEGWTKVVLKAAA
CCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]