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The map label for this gene is rho [H]

Identifier: 238027054

GI number: 238027054

Start: 1577136

End: 1578398

Strand: Reverse

Name: rho [H]

Synonym: bglu_1g14330

Alternate gene names: 238027054

Gene position: 1578398-1577136 (Counterclockwise)

Preceding gene: 238027055

Following gene: 238027053

Centisome position: 40.4

GC content: 61.68

Gene sequence:

>1263_bases
ATGCATTTATCCGAGCTCAAGTCTCTGCACGTGTCCGAATTGATCGAAATGGCCAACGGCCTGGAGATCGAAAACGCGAA
CCGCCTGCGCAAGCAGGAGCTGATGTTCGCCATTCTAAAAAAGCGCGCCAAGACGGGAGAGACGATCTTCGGCGACGGCA
CGCTCGAAGTCCTGCCGGACGGCTTCGGTTTCCTGCGCTCGCCCGAAATGTCGTATCTCGCGAGCACGGACGACATCTAT
ATCAGCCCGTCGCAGATCCGCCGCTTCAACCTGCATACCGGCGACACGATCGAAGGTGAGGTCCGCACGCCGAAGGACGG
CGAGCGCTACTTCGCACTGGTCAAGGTCGACAAAGTCAACGGGCAGCCGCCCGAGGCCTCGAAACACAAGATCATGTTCG
AGAACCTCACGCCGCTGCACCCGAACAAGCCGCTTTCGCTCGAACGCGAAATGCGCGGCGAGGAAAACGTGACGGGCCGC
ATCATCGACATGATCGCGCCGATCGGCAAGGGCCAGCGCGGCCTGCTGGTCGCCTCGCCGAAGTCGGGCAAGACCGTGAT
GCTCCAGCACATCGCGCACGCGATCAAGCAGAACCACCCGGACGTGATTCTGTTCGTGCTGCTGATCGACGAGCGTCCGG
AAGAAGTGACGGAAATGCAGCGCTCGGTGGCGGGCGAAGTGATCGCCTCGACCTTCGACGAACCGGCCACGCGCCACGTG
CAGGTCGCCGAAATGGTGATCGAGAAGGCCAAGCGCCTGGTGGAAATGAAGCACGACGTGGTGATCCTGCTCGACTCGAT
CACGCGTCTCGCGCGCGCCTACAACACCGTGATCCCGGCCTCGGGCAAGGTGCTCACGGGCGGCGTCGACGCCAACGCCC
TGCAGCGCCCGAAGCGCTTCTTCGGCGCGGCGCGCAACATCGAGGAAGGCGGCTCGCTGACCATCATCGGTACCGCGCTG
ATCGAAACCGGCAGCCGCATGGACGACGTGATCTACGAAGAGTTCAAGGGCACCGGCAACATGGAAGTCCACCTGGAACG
CCGTCTCGCGGAAAAGCGCGTCTACCCGTCGATCAACCTGAACAAGTCGGGCACGCGCCGCGAGGAAATGCTGATCAAGG
CCGACATCCTTCAGAAGATCTGGGTGCTGCGCAAGTTCATCCACGACATGGACGAAGTCGAGGCGATGGAATTCCTGCTC
GACAAGATTCGCCAGACCAAGAGCAATTCCGAGTTCTTCGACCTGATGCGCCGCGGCGGCTGA

Upstream 100 bases:

>100_bases
AATTAGACGTCGCCATCCGACGCAAAAGTCTCAGAGCGTTTCCGCTCGCCCTCCTCCCTATTTCTTTCGTCGCATCTCTC
CTCCCTGGCGGGTTCTCCGT

Downstream 100 bases:

>100_bases
GCCCGCGCCAGGCCGGCACGAGTCGCGCAACGCAGCAGGAAAGCCGCCAGAAGCCGCCCGCCGGGCGGCTTTTTCATGCC
CGAATCTGTACGTGTACGTG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHLSELKSLHVSELIEMANGLEIENANRLRKQELMFAILKKRAKTGETIFGDGTLEVLPDGFGFLRSPEMSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNGQPPEASKHKIMFENLTPLHPNKPLSLEREMRGEENVTGR
IIDMIAPIGKGQRGLLVASPKSGKTVMLQHIAHAIKQNHPDVILFVLLIDERPEEVTEMQRSVAGEVIASTFDEPATRHV
QVAEMVIEKAKRLVEMKHDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPSINLNKSGTRREEMLIKADILQKIWVLRKFIHDMDEVEAMEFLL
DKIRQTKSNSEFFDLMRRGG

Sequences:

>Translated_420_residues
MHLSELKSLHVSELIEMANGLEIENANRLRKQELMFAILKKRAKTGETIFGDGTLEVLPDGFGFLRSPEMSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNGQPPEASKHKIMFENLTPLHPNKPLSLEREMRGEENVTGR
IIDMIAPIGKGQRGLLVASPKSGKTVMLQHIAHAIKQNHPDVILFVLLIDERPEEVTEMQRSVAGEVIASTFDEPATRHV
QVAEMVIEKAKRLVEMKHDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPSINLNKSGTRREEMLIKADILQKIWVLRKFIHDMDEVEAMEFLL
DKIRQTKSNSEFFDLMRRGG
>Mature_420_residues
MHLSELKSLHVSELIEMANGLEIENANRLRKQELMFAILKKRAKTGETIFGDGTLEVLPDGFGFLRSPEMSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNGQPPEASKHKIMFENLTPLHPNKPLSLEREMRGEENVTGR
IIDMIAPIGKGQRGLLVASPKSGKTVMLQHIAHAIKQNHPDVILFVLLIDERPEEVTEMQRSVAGEVIASTFDEPATRHV
QVAEMVIEKAKRLVEMKHDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPSINLNKSGTRREEMLIKADILQKIWVLRKFIHDMDEVEAMEFLL
DKIRQTKSNSEFFDLMRRGG

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=418, Percent_Identity=69.1387559808612, Blast_Score=614, Evalue=1e-177,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47362; Mature: 47362

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSELKSLHVSELIEMANGLEIENANRLRKQELMFAILKKRAKTGETIFGDGTLEVLPD
CCHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEECCC
GFGFLRSPEMSYLASTDDIYISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVN
CCCCCCCCCHHHEECCCCEEECHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
GQPPEASKHKIMFENLTPLHPNKPLSLEREMRGEENVTGRIIDMIAPIGKGQRGLLVASP
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECC
KSGKTVMLQHIAHAIKQNHPDVILFVLLIDERPEEVTEMQRSVAGEVIASTFDEPATRHV
CCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
QVAEMVIEKAKRLVEMKHDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNIEEGGSLTIIGTALIETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPSINL
HHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCC
NKSGTRREEMLIKADILQKIWVLRKFIHDMDEVEAMEFLLDKIRQTKSNSEFFDLMRRGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHLSELKSLHVSELIEMANGLEIENANRLRKQELMFAILKKRAKTGETIFGDGTLEVLPD
CCHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEECCC
GFGFLRSPEMSYLASTDDIYISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVN
CCCCCCCCCHHHEECCCCEEECHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
GQPPEASKHKIMFENLTPLHPNKPLSLEREMRGEENVTGRIIDMIAPIGKGQRGLLVASP
CCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECC
KSGKTVMLQHIAHAIKQNHPDVILFVLLIDERPEEVTEMQRSVAGEVIASTFDEPATRHV
CCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
QVAEMVIEKAKRLVEMKHDVVILLDSITRLARAYNTVIPASGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNIEEGGSLTIIGTALIETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPSINL
HHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCC
NKSGTRREEMLIKADILQKIWVLRKFIHDMDEVEAMEFLLDKIRQTKSNSEFFDLMRRGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]