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The map label for this gene is tig [H]

Identifier: 238026972

GI number: 238026972

Start: 1480235

End: 1481581

Strand: Direct

Name: tig [H]

Synonym: bglu_1g13490

Alternate gene names: 238026972

Gene position: 1480235-1481581 (Clockwise)

Preceding gene: 238026967

Following gene: 238026973

Centisome position: 37.89

GC content: 64.37

Gene sequence:

>1347_bases
ATGGCTAACGTTGTTGAAAACCTCGGCAAGCTCGAACGCCGTGTGACGATTTCCCTGCCGAAGGAAGTCGTGCAGAAGGA
GATCGACGCCCGTATTCAGAAACTCGCGAAGAACGTGCGCATGCCGGGTTTCCGCCCGGGCAAGGTGCCGCTCAAGATGG
TCGCGCAACAATACGCGGGCCAGGTCGAGGCAGAAGTGCTGAGCGACAAGATCGGCCAGGAATTCTTCGAAGTCAGCCGC
GCGGAAAACCTGCGCGTGGCGGGCCAGCCGAGCTTCGCGCCGAAGCAGGATGCGGCCGCCGATGCCTACGCCTTCGACGC
GACGTTCGAGGTTTACCCGGAGGTCAAGATCGGTGATCTGGCCACGGCGGAAGTCGAGCGCTCGACCACCACCATTGGCG
ATGCCGAGATCGACCGCACGCTCGACATCCTGCGCAAGCAGCGCGTGCACTACCACGTGCGCGGCGAAGGCGGCGAGCAC
GGCGACGGCGGCGCGGAGCAGGCCGCCCAGCAAGGCGACCGCGTGACGGTGGACTTCGTCGGCAAGATCGACGACGTCGC
GTTCCAGGGCGGCACGGCCGAGGACTTCCCGTTCGTGCTCGGCGAAGGCCGGATGCTGCCGGAGTTCGAGCAGGCCGCGC
TGGGCCTGAAGGTCGGCGAGTCGCGCGAATTCGATCTGACCTTCCCCGAGGACTATCACGGCAAGGATGTGGCCGGCAAG
ACCGCGAAGTTCACGGTCACGATGAAGAAGGTCGAATGGCCGCATCTGCCGGAAATCGACGCGGAGTTCGCGAAGACGCT
CGGCATCGAGGACGGCGATCTGGCCAAGATGCGCGCCGAGATCAAGGAAAACCTCGAGCGTGAAGCGAAGCGCCGCACTC
AGTCGCTGGTGAAGAACCAGGTGATGGACGCGGTCCTGAAGATTTCCGAACTCGACGTGCCGAACGCGCTCGTCGCGCAG
GATCAGGAGCGCCTCGTCGAGATGGCGCGCCAGGACCTCGTGCAACGCGGCGTGCCGAACGCGGCCACCGCGCCGATCCC
GGTCGAGATGTTCAAGGAGCAGGCCGAGCGCCGCGTCAAGCTGGGCCTCGTGATCGCCGAGCTGGTGAAGGCCAACGGCC
TCGAAGCGAAGCCCGAGCAGATCCGTGCCGAAGTCGACGAGTTCGCGAAGAGCTACGAAGACCCGAAGGAAGTGGTCCGC
TGGTATTATTCGAACCAGCAGCGCCTGGCCGAAATGGAAGCGTTCGTCGTCGAGAGCAACGTCGTCGACTTCGTGCTCGG
CAAGGCGAAGGTGACGGACAAGGAAGTGAGCTTCGAGGCACTGGCAAGCGCATCGGCGCAGGCCTAA

Upstream 100 bases:

>100_bases
GCCGAACGTATGGAACCGCGGCGCGCGACGCAGCAGCGTCATGAGGCAGGCACGGCAAGGAAAACCGATTCGCTCGAATA
ATTTTAGGACGATTGAAGCC

Downstream 100 bases:

>100_bases
GCGTCGTTTCAGCGGCGTGCCGGCTGTCGGAGCGACGGCCCGCACGCCGTTTTTGCGTCGGTGTCCGAAGGCCGGCATGC
CGGCGGATTCGCGCCGGCGG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MANVVENLGKLERRVTISLPKEVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFEVSR
AENLRVAGQPSFAPKQDAAADAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHYHVRGEGGEH
GDGGAEQAAQQGDRVTVDFVGKIDDVAFQGGTAEDFPFVLGEGRMLPEFEQAALGLKVGESREFDLTFPEDYHGKDVAGK
TAKFTVTMKKVEWPHLPEIDAEFAKTLGIEDGDLAKMRAEIKENLEREAKRRTQSLVKNQVMDAVLKISELDVPNALVAQ
DQERLVEMARQDLVQRGVPNAATAPIPVEMFKEQAERRVKLGLVIAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVR
WYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASASAQA

Sequences:

>Translated_448_residues
MANVVENLGKLERRVTISLPKEVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFEVSR
AENLRVAGQPSFAPKQDAAADAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHYHVRGEGGEH
GDGGAEQAAQQGDRVTVDFVGKIDDVAFQGGTAEDFPFVLGEGRMLPEFEQAALGLKVGESREFDLTFPEDYHGKDVAGK
TAKFTVTMKKVEWPHLPEIDAEFAKTLGIEDGDLAKMRAEIKENLEREAKRRTQSLVKNQVMDAVLKISELDVPNALVAQ
DQERLVEMARQDLVQRGVPNAATAPIPVEMFKEQAERRVKLGLVIAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVR
WYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASASAQA
>Mature_447_residues
ANVVENLGKLERRVTISLPKEVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFEVSRA
ENLRVAGQPSFAPKQDAAADAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHYHVRGEGGEHG
DGGAEQAAQQGDRVTVDFVGKIDDVAFQGGTAEDFPFVLGEGRMLPEFEQAALGLKVGESREFDLTFPEDYHGKDVAGKT
AKFTVTMKKVEWPHLPEIDAEFAKTLGIEDGDLAKMRAEIKENLEREAKRRTQSLVKNQVMDAVLKISELDVPNALVAQD
QERLVEMARQDLVQRGVPNAATAPIPVEMFKEQAERRVKLGLVIAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRW
YYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASASAQA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=443, Percent_Identity=39.2776523702032, Blast_Score=327, Evalue=1e-90,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 49691; Mature: 49560

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVVENLGKLERRVTISLPKEVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAG
CCHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKIGQEFFEVSRAENLRVAGQPSFAPKQDAAADAYAFDATFEVYPEVKIGDL
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCEEEECCCCEECCC
ATAEVERSTTTIGDAEIDRTLDILRKQRVHYHVRGEGGEHGDGGAEQAAQQGDRVTVDFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCCEEEEEEC
GKIDDVAFQGGTAEDFPFVLGEGRMLPEFEQAALGLKVGESREFDLTFPEDYHGKDVAGK
CCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHCCEECCCCCEECCCCCCCCCCCCCCC
TAKFTVTMKKVEWPHLPEIDAEFAKTLGIEDGDLAKMRAEIKENLEREAKRRTQSLVKNQ
CEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMDAVLKISELDVPNALVAQDQERLVEMARQDLVQRGVPNAATAPIPVEMFKEQAERRVK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGLVIAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESN
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
VVDFVLGKAKVTDKEVSFEALASASAQA
HHHHHHCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ANVVENLGKLERRVTISLPKEVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAG
CHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKIGQEFFEVSRAENLRVAGQPSFAPKQDAAADAYAFDATFEVYPEVKIGDL
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCEEEECCCCEECCC
ATAEVERSTTTIGDAEIDRTLDILRKQRVHYHVRGEGGEHGDGGAEQAAQQGDRVTVDFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCCEEEEEEC
GKIDDVAFQGGTAEDFPFVLGEGRMLPEFEQAALGLKVGESREFDLTFPEDYHGKDVAGK
CCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHCCEECCCCCEECCCCCCCCCCCCCCC
TAKFTVTMKKVEWPHLPEIDAEFAKTLGIEDGDLAKMRAEIKENLEREAKRRTQSLVKNQ
CEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMDAVLKISELDVPNALVAQDQERLVEMARQDLVQRGVPNAATAPIPVEMFKEQAERRVK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGLVIAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESN
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
VVDFVLGKAKVTDKEVSFEALASASAQA
HHHHHHCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA