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The map label for this gene is clpP [H]

Identifier: 238026973

GI number: 238026973

Start: 1481724

End: 1482377

Strand: Direct

Name: clpP [H]

Synonym: bglu_1g13500

Alternate gene names: 238026973

Gene position: 1481724-1482377 (Clockwise)

Preceding gene: 238026972

Following gene: 238026974

Centisome position: 37.93

GC content: 62.54

Gene sequence:

>654_bases
ATGATCAATCGCGCTGAATTGCTGGACACGCTGGCTTCCCATGCACCGCAGGATTTCGAAACGAAGGCGCTCGGACTGGT
GCCGATCGTCGTCGAGACGAGCGGCCGCGGCGAGCGTTCCTACGACATCTACTCGCGCCTGCTGAAGGAGCGGATCGTGT
TCATGGTCGGCGAAGTGAACGACCAGACCGCGAATCTCGTGGTGGCCCAGTTGCTGTTTCTCGAGAGCGAGAATCCCGAC
AAGGACATCAGCCTCTACATCAACAGCCCGGGCGGATCGGTCTCGGCGGGCCTCGCGATCTACGACACGATGCAGTTCAT
CAAGCCGGACGTGTCGACGCTCTGCATGGGCCTCGCGGCCAGCATGGGCGCGTTCCTGCTGTCGTCGGGCGCGAAGGGCA
AGCGCTACGCGCTGCCGAATGCGCGCGTGATGATCCACCAGCCGCTCGGCGGCGCGCGCGGCCAGGCCTCGGACATCGAG
ATCCAGGCGCGCGAGATCCTCTATCTCCGCGAGCGTCTGAACAAGATTCTCGCCGAGAATACGGGTCAGGACGTCGAGCG
CATCGCTCGCGACACGGATCGTGATAATTTCATGTCCAGCGACGATGCGAAGGCGTATGGCCTGATCGATCACGTATCGG
CAAAGCGTCCGTGA

Upstream 100 bases:

>100_bases
CACGCCGTTTTTGCGTCGGTGTCCGAAGGCCGGCATGCCGGCGGATTCGCGCCGGCGGCGCTTCCTCCGTTCAACATTCA
TTTCGGACAAGGCTCATTGC

Downstream 100 bases:

>100_bases
TGAAGCAAACGGGGCGCTGCTCCCCTTGGGGCGGCGCCCGCGCCCCGAGCATCTGCGGCTAGACCAGCACGGCCGGCGAA
TACCCATGTCGATGTCATGG

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MINRAELLDTLASHAPQDFETKALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPD
KDISLYINSPGGSVSAGLAIYDTMQFIKPDVSTLCMGLAASMGAFLLSSGAKGKRYALPNARVMIHQPLGGARGQASDIE
IQAREILYLRERLNKILAENTGQDVERIARDTDRDNFMSSDDAKAYGLIDHVSAKRP

Sequences:

>Translated_217_residues
MINRAELLDTLASHAPQDFETKALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPD
KDISLYINSPGGSVSAGLAIYDTMQFIKPDVSTLCMGLAASMGAFLLSSGAKGKRYALPNARVMIHQPLGGARGQASDIE
IQAREILYLRERLNKILAENTGQDVERIARDTDRDNFMSSDDAKAYGLIDHVSAKRP
>Mature_217_residues
MINRAELLDTLASHAPQDFETKALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPD
KDISLYINSPGGSVSAGLAIYDTMQFIKPDVSTLCMGLAASMGAFLLSSGAKGKRYALPNARVMIHQPLGGARGQASDIE
IQAREILYLRERLNKILAENTGQDVERIARDTDRDNFMSSDDAKAYGLIDHVSAKRP

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=197, Percent_Identity=56.8527918781726, Blast_Score=239, Evalue=1e-63,
Organism=Escherichia coli, GI1786641, Length=193, Percent_Identity=66.3212435233161, Blast_Score=289, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17538017, Length=186, Percent_Identity=54.3010752688172, Blast_Score=215, Evalue=1e-56,
Organism=Drosophila melanogaster, GI20129427, Length=196, Percent_Identity=55.1020408163265, Blast_Score=239, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 23789; Mature: 23789

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRAELLDTLASHAPQDFETKALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVN
CCCHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
DQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGLAIYDTMQFIKPDVSTLCMGLAA
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
SMGAFLLSSGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLRERLNKILAEN
HHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TGQDVERIARDTDRDNFMSSDDAKAYGLIDHVSAKRP
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MINRAELLDTLASHAPQDFETKALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVN
CCCHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
DQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGLAIYDTMQFIKPDVSTLCMGLAA
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
SMGAFLLSSGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLRERLNKILAEN
HHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TGQDVERIARDTDRDNFMSSDDAKAYGLIDHVSAKRP
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA