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The map label for this gene is map [H]

Identifier: 238026901

GI number: 238026901

Start: 1394305

End: 1395114

Strand: Reverse

Name: map [H]

Synonym: bglu_1g12710

Alternate gene names: 238026901

Gene position: 1395114-1394305 (Counterclockwise)

Preceding gene: 238026910

Following gene: 238026900

Centisome position: 35.71

GC content: 65.31

Gene sequence:

>810_bases
ATGTCCATCACGATCAAGAACGATCACGATATCGAGCAGATGCGCGTCGCATGCCGGCTCGCGAGCGAAGTGCTCGACTA
CATCACGCCGTTCGTCGTCGCGGGCACCACGACGGGCGAGCTGGACCGGCTCTGCCACGAGTACATGACCAATGTGCAAG
GCACCGTGCCCGCGCCGCTCAACTACCAGCCGCCCGGCTATCCGCCCTACCCGAAGGCGATCTGCACCTCGGTCAACGAC
GTGATCTGCCACGGCATTCCCGGCGACAAGGTGCTGAAGAACGGCGACGCGCTCAACATCGACATCACCGTGATCAAGAA
CGGCTATTTCGGCGACACGAGCCGGATGTTCCTGATCGGCGAGGGCTCGATCCTGGCCAAGCGGCTGATCCAGACCACCT
ATGAATGCATGTGGCTCGGCATCGAGCAGGTCAGGCCCGGCGCGCACCTCGGCGACATCGGCCATGCGATCCAGAAGCAT
GCGGAAAGCCGCGGCTACAGCGTGGTGCGCGAGTATTGCGGGCACGGCATCGGCACGGTGTTCCACGAGGATCCGCAGGT
GGTCCATTACGGCCGGCCCGGCACCGGCATCGAGATCGTGCCGGGCATGATCTTCACGATCGAGCCGATGATCAACGCCG
GCAAGCGCGACATCCGTACCATGCCGGACCAGTGGACCGTCAAGACGCGCGATCGCAGCCTCTCGGCGCAATGGGAGCAC
ACCGTGCTCGTCACGCCGAGCGGCTATGAAGTGCTGACGGTGTCGGCCGGCACGCCGGCGCGGCCGGCGCTCGACGCGGC
GGCGGCCTGA

Upstream 100 bases:

>100_bases
GTTCCGCCCGAAACCCATGCCGGACAAGCCACGCGACGGCTGCGACCACCCCGATTCGATGCGATAATCCCGGGATTCCA
GGCATTCCAGGTCACCAATC

Downstream 100 bases:

>100_bases
GGCGGGCGGCCCGCCGCCGGCGCGCCGTCCGGCCGGATGGCGGTCGCGCCGGGCCGGCAGCGCGGCACGCGCCGCGCAGG
CCACGCGCCCGGTCCGCCCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSITIKNDHDIEQMRVACRLASEVLDYITPFVVAGTTTGELDRLCHEYMTNVQGTVPAPLNYQPPGYPPYPKAICTSVND
VICHGIPGDKVLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLIQTTYECMWLGIEQVRPGAHLGDIGHAIQKH
AESRGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIEIVPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTPSGYEVLTVSAGTPARPALDAAAA

Sequences:

>Translated_269_residues
MSITIKNDHDIEQMRVACRLASEVLDYITPFVVAGTTTGELDRLCHEYMTNVQGTVPAPLNYQPPGYPPYPKAICTSVND
VICHGIPGDKVLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLIQTTYECMWLGIEQVRPGAHLGDIGHAIQKH
AESRGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIEIVPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TVLVTPSGYEVLTVSAGTPARPALDAAAA
>Mature_268_residues
SITIKNDHDIEQMRVACRLASEVLDYITPFVVAGTTTGELDRLCHEYMTNVQGTVPAPLNYQPPGYPPYPKAICTSVNDV
ICHGIPGDKVLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLIQTTYECMWLGIEQVRPGAHLGDIGHAIQKHA
ESRGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIEIVPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEHT
VLVTPSGYEVLTVSAGTPARPALDAAAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=260, Percent_Identity=46.9230769230769, Blast_Score=233, Evalue=9e-62,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=39.6825396825397, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=57.6470588235294, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1788728, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71996291, Length=257, Percent_Identity=43.579766536965, Blast_Score=213, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=44.8818897637795, Blast_Score=217, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21355531, Length=261, Percent_Identity=46.360153256705, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=38.1526104417671, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29446; Mature: 29315

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITIKNDHDIEQMRVACRLASEVLDYITPFVVAGTTTGELDRLCHEYMTNVQGTVPAPL
CEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
NYQPPGYPPYPKAICTSVNDVICHGIPGDKVLKNGDALNIDITVIKNGYFGDTSRMFLIG
CCCCCCCCCCCHHHHHCHHHHEECCCCCHHHCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLIQTTYECMWLGIEQVRPGAHLGDIGHAIQKHAESRGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCE
FHEDPQVVHYGRPGTGIEIVPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCCEECCCEEEEEEHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTPSGYEVLTVSAGTPARPALDAAAA
EEEECCCCCEEEEEECCCCCCCCHHHCCC
>Mature Secondary Structure 
SITIKNDHDIEQMRVACRLASEVLDYITPFVVAGTTTGELDRLCHEYMTNVQGTVPAPL
EEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
NYQPPGYPPYPKAICTSVNDVICHGIPGDKVLKNGDALNIDITVIKNGYFGDTSRMFLIG
CCCCCCCCCCCHHHHHCHHHHEECCCCCHHHCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLIQTTYECMWLGIEQVRPGAHLGDIGHAIQKHAESRGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCE
FHEDPQVVHYGRPGTGIEIVPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
ECCCCCEEEECCCCCCCEECCCEEEEEEHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCE
TVLVTPSGYEVLTVSAGTPARPALDAAAA
EEEECCCCCEEEEEECCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]