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The map label for this gene is gltX [H]

Identifier: 238026868

GI number: 238026868

Start: 1351339

End: 1352739

Strand: Direct

Name: gltX [H]

Synonym: bglu_1g12360

Alternate gene names: 238026868

Gene position: 1351339-1352739 (Clockwise)

Preceding gene: 238026867

Following gene: 238026869

Centisome position: 34.59

GC content: 65.88

Gene sequence:

>1401_bases
ATGACACGTCAAGTCCGTACCCGTTTCGCGCCGAGTCCGACCGGCTTCATACATCTCGGCAACATCCGCTCCGCCCTCTA
CCCGTGGGCCTTCGCCCGCAGCACTCAAGGCGTGTTCGTGCTGCGCATCGAGGACACGGACGTGGAGCGCTCGTCGGACG
TCGCTGTCGACGCGATCCTCGAAGGCATGAAGTGGCTCGATCTCGATTTTGACGAAGGCCCGTTCTACCAGATGCAGCGC
ATGGACCGCTATCGCGAGGTGCTGGCGCAGATGGTCGAAAAGGGGCTCGCGTACCCATGCTACATGTCCACCGAGGAACT
CGACGCGGTGCGCGAGCGCCAGCGCGAGGCCGGTGAGAAGCCGCGCTACGACGGCACCTGGCGGCCGGAGCCGGGCAAGG
TGCTGCCGCAGCCGCCCGCGGGCGTGCAGCCGGTGCTGCGTTTCCGCAACCCGCTGACGGGCTCGGTGGTCTGGGACGAC
GCCGTGAAGGGCCGCATCGAGATCTCGAACGAGGAACTGGACGATCTCGTGATTGCGCGGCCGGACGGCACGCCTACCTA
TAATTTCTGTGTTGTCGTCGACGATCTCGACATGAACATCACGCACGTGATTCGCGGCGACGACCATGTCAACAACACGC
CGCGCCAGATCAACATCCTGCGCGCGCTCGGCGGGGAAGTGCCTGTTTACGCGCATCTGCCCACCGTGCTCAACGAGCAG
GGCGAGAAGATGAGCAAGCGTCACGGCGCGATGAGCGTGATGGGCTACCGCGATGCAGGCTATCTGCCCGAGGCGGTGCT
CAATTATCTCGCGCGGCTCGGCTGGTCGCACGGCGACGCCGAGATCTTCTCGCGCGAGCAGTTCGTGGCGTGGTTCGATC
TCGAGCATCTCGGCAAGTCGCCGGCGCAGTACGACTTGGCCAAGCTGAACTGGTTCAACAACCATTACATCAAGGAAGCC
GACAACGCGCGCCTCGCGGCGCTCGCCAAGCCGTTTTTCGCGGCGCTCGGCATCGACGACACGGCACTGGAGAGCGGCCC
GGAACTGGCTGCCGTGATCGGCCTGATGAAGGATCGCGCCTCGACCGTCAAGGAGATCGCCGAGGGCGCGGCGATGTTCT
ATCGCATCCCGGCGCCCGACGCAGACGAACTCGCGCAGCGTGTGACCGAGGCCGTGAAGCCGGCGCTCGCGGCCTTCACC
GAGGCGCTGAAGACGGCCGAGTGGAGCAAGGAAGGCATCGCCGCCGCGCTGAAGGCGACGCTCGCCGCGCACGGGCTCAA
GATGCCGGCGCTGGCCATGCCGGTGCGGCTGCTGGTGGTCGGCACCACGCATACGCCATCGCTCGACGCCGTGCTCGCGC
TGTTCGAGCGCGACGTGGTGATTTCGCGGCTCAGCGCATGA

Upstream 100 bases:

>100_bases
TCGTTCCGGTGCCGGCGGTTTCGCGCAGTCGCTCGCGGCGTGCGCCGTCACCGCACCATCATTCATCGGGCCGCCGCGAG
CGGCCATCGAGCTACCGTCC

Downstream 100 bases:

>100_bases
GAGCGTGATCGACAAGGCTGAACGGGGCGGCGCGCGGCGCGGCTGACGTGGCCGCACGCCTCCTATGCCCTAGCTTGCCG
ATGTTTCGCAAAAAATTTTG

Product: glutamyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamate--tRNA ligase; GluRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTRQVRTRFAPSPTGFIHLGNIRSALYPWAFARSTQGVFVLRIEDTDVERSSDVAVDAILEGMKWLDLDFDEGPFYQMQR
MDRYREVLAQMVEKGLAYPCYMSTEELDAVRERQREAGEKPRYDGTWRPEPGKVLPQPPAGVQPVLRFRNPLTGSVVWDD
AVKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMNITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQ
GEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVAWFDLEHLGKSPAQYDLAKLNWFNNHYIKEA
DNARLAALAKPFFAALGIDDTALESGPELAAVIGLMKDRASTVKEIAEGAAMFYRIPAPDADELAQRVTEAVKPALAAFT
EALKTAEWSKEGIAAALKATLAAHGLKMPALAMPVRLLVVGTTHTPSLDAVLALFERDVVISRLSA

Sequences:

>Translated_466_residues
MTRQVRTRFAPSPTGFIHLGNIRSALYPWAFARSTQGVFVLRIEDTDVERSSDVAVDAILEGMKWLDLDFDEGPFYQMQR
MDRYREVLAQMVEKGLAYPCYMSTEELDAVRERQREAGEKPRYDGTWRPEPGKVLPQPPAGVQPVLRFRNPLTGSVVWDD
AVKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMNITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQ
GEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVAWFDLEHLGKSPAQYDLAKLNWFNNHYIKEA
DNARLAALAKPFFAALGIDDTALESGPELAAVIGLMKDRASTVKEIAEGAAMFYRIPAPDADELAQRVTEAVKPALAAFT
EALKTAEWSKEGIAAALKATLAAHGLKMPALAMPVRLLVVGTTHTPSLDAVLALFERDVVISRLSA
>Mature_465_residues
TRQVRTRFAPSPTGFIHLGNIRSALYPWAFARSTQGVFVLRIEDTDVERSSDVAVDAILEGMKWLDLDFDEGPFYQMQRM
DRYREVLAQMVEKGLAYPCYMSTEELDAVRERQREAGEKPRYDGTWRPEPGKVLPQPPAGVQPVLRFRNPLTGSVVWDDA
VKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMNITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQG
EKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVAWFDLEHLGKSPAQYDLAKLNWFNNHYIKEAD
NARLAALAKPFFAALGIDDTALESGPELAAVIGLMKDRASTVKEIAEGAAMFYRIPAPDADELAQRVTEAVKPALAAFTE
ALKTAEWSKEGIAAALKATLAAHGLKMPALAMPVRLLVVGTTHTPSLDAVLALFERDVVISRLSA

Specific function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction:glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) [H]

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=327, Percent_Identity=35.474006116208, Blast_Score=197, Evalue=3e-50,
Organism=Escherichia coli, GI1788743, Length=470, Percent_Identity=49.1489361702128, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI226510925, Length=249, Percent_Identity=37.7510040160643, Blast_Score=141, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71993394, Length=340, Percent_Identity=33.5294117647059, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324540, Length=335, Percent_Identity=37.0149253731343, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6321192, Length=234, Percent_Identity=25.2136752136752, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24665321, Length=493, Percent_Identity=27.1805273833671, Blast_Score=194, Evalue=8e-50,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR004527
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: =6.1.1.17 [H]

Molecular weight: Translated: 51762; Mature: 51630

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQVRTRFAPSPTGFIHLGNIRSALYPWAFARSTQGVFVLRIEDTDVERSSDVAVDAIL
CCCCCCCCCCCCCCCEEEECCHHHHHCCHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHH
EGMKWLDLDFDEGPFYQMQRMDRYREVLAQMVEKGLAYPCYMSTEELDAVRERQREAGEK
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
PRYDGTWRPEPGKVLPQPPAGVQPVLRFRNPLTGSVVWDDAVKGRIEISNEELDDLVIAR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCEEEECCCCCCCEEEEC
PDGTPTYNFCVVVDDLDMNITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQ
CCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
GEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVAWFDLEHLGKS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEHHHHCCC
PAQYDLAKLNWFNNHYIKEADNARLAALAKPFFAALGIDDTALESGPELAAVIGLMKDRA
CCCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHH
STVKEIAEGAAMFYRIPAPDADELAQRVTEAVKPALAAFTEALKTAEWSKEGIAAALKAT
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAHGLKMPALAMPVRLLVVGTTHTPSLDAVLALFERDVVISRLSA
HHHCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRQVRTRFAPSPTGFIHLGNIRSALYPWAFARSTQGVFVLRIEDTDVERSSDVAVDAIL
CCCCCCCCCCCCCCEEEECCHHHHHCCHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHH
EGMKWLDLDFDEGPFYQMQRMDRYREVLAQMVEKGLAYPCYMSTEELDAVRERQREAGEK
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
PRYDGTWRPEPGKVLPQPPAGVQPVLRFRNPLTGSVVWDDAVKGRIEISNEELDDLVIAR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCEEEECCCCCCCEEEEC
PDGTPTYNFCVVVDDLDMNITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQ
CCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
GEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVAWFDLEHLGKS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEHHHHCCC
PAQYDLAKLNWFNNHYIKEADNARLAALAKPFFAALGIDDTALESGPELAAVIGLMKDRA
CCCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHH
STVKEIAEGAAMFYRIPAPDADELAQRVTEAVKPALAAFTEALKTAEWSKEGIAAALKAT
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAHGLKMPALAMPVRLLVVGTTHTPSLDAVLALFERDVVISRLSA
HHHCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA