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The map label for this gene is phoR [H]

Identifier: 238026793

GI number: 238026793

Start: 1262950

End: 1264260

Strand: Direct

Name: phoR [H]

Synonym: bglu_1g11510

Alternate gene names: 238026793

Gene position: 1262950-1264260 (Clockwise)

Preceding gene: 238026792

Following gene: 238026795

Centisome position: 32.33

GC content: 68.19

Gene sequence:

>1311_bases
ATGAACATCATCTGGGTGCGCTTCCTGGTGTCGCTCGTGCTGCTCGCGCTGGCCGCGATACTGGCCGGCGTGACAATCGG
CCTGCGCGCGGGCCTCACCGTCGGCGTCGTGCTGCTGGTCGCCCAGGCGTTCTTCACCACGTTTCACACGCAGCGCCTCT
GGCGGCTGCTCGACGCGCCCGTCTACGGCGAGGTGCCGAGCGCGCCGGGCATCTGGGGCGAGATCTACTACCGGCTGCAC
AAGCTCGCCAAGCAGTGGCACGCGCAGGTGCGCCAGGTCGAGCAGCAGCATTCACGCTTCATCCAGGCGATCCAGGCCTC
GCCGAACGGCGTGGCGATGCTCGACGACCATGACCAGATCGAATGGTGCAATGCGATCGCCGAGCTGCATTTCGGGCTCG
ACGCGAAGCGCGACCTGCGCCAGCACATCACGCATCTGGTCCGGCATCCCGACTTCGTGCGCTACCTGAACTCGCAGCAC
TACGACGAGATGGTGGTGATGCGCGGCATGGGCGAGGGGCGCCAGCACGTGATCGCGGTGCAGGTGTTCCCCTACGGCGA
CAACCGCAAGCTGCTGCTCACGCAGGACATCACCGAGGTCGAGCGCACCGACGCGATGCGGCGCGACTTCGTGGCCAACG
TCTCGCACGAGCTGAAGACGCCGCTCACGGTGCTCTCCGGCTTCCTCGAGACGCTGCGCGAGCTGCCGCTGTCCGACGAC
GAGCGCGCGCGCTACCTCGACATGATGGAGCAGCAGGCCTCGCGCATGCGCAAGATCGTCACCGACCTGCTGGTGCTCGC
CAAGCTCGAAGGCGAGGGCAAGCCGCCCACCGACAAGCCGGTCGACATGGACGACGTGCTCGGCCACCTCGAGGACGTCG
CGCAGACGCTGTCGGCCGGCCACCACGAGATCAGCTTCGAGATCGACGAGACGCTGACCGTGACGGGTGCCGAGACCGAG
ATCTTCAGCGCGCTCGGCAACCTCGTGACGAATGCGGTGCGCTACACGCCCGAGGGCGGCAAGATCCGCGTGAGCTGGCG
CCGCGACGGCGCGCAGGCCGTGTTCTCGGTCAAGGACAGCGGCTTCGGGATTCCGGCCGAGGACCTGCCGCGGCTCACCG
AACGCTTCTACCGCGTCGATCGCAGCCGTTCGCGCGACACCGGCGGCACCGGCCTTGGCCTGGCGATCGTCAAGCACGTG
CTGCAGCGCCACGACGGGCAGCTGCTGATCCAGAGCGAGGAAGGGCGCGGCAGCACGTTCACGGCGCGCTTTCCGGCGCA
GCGCACGATCCGCCGGCAGCATGCGGCGTGA

Upstream 100 bases:

>100_bases
CGGCAGCGGCTACCGCCTCGCCAAGCATGCCTGACCTGGCACGGCGCGCGTGCCGCGCGCCGTCTCTCACCGTTCTCCCG
TCTTCTTTCTCGCGCCAGCC

Downstream 100 bases:

>100_bases
GATGAGGCGCGTGAGACCGGCCGCGTGAGGCCGGCCAGACGAACAAGGCCGCCCGGTTCACCCCCGGGCGGCCTTTGCTT
CGACGCGGCCGCGGCGGCGC

Product: phosphate regulon sensor protein PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNIIWVRFLVSLVLLALAAILAGVTIGLRAGLTVGVVLLVAQAFFTTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAELHFGLDAKRDLRQHITHLVRHPDFVRYLNSQH
YDEMVVMRGMGEGRQHVIAVQVFPYGDNRKLLLTQDITEVERTDAMRRDFVANVSHELKTPLTVLSGFLETLRELPLSDD
ERARYLDMMEQQASRMRKIVTDLLVLAKLEGEGKPPTDKPVDMDDVLGHLEDVAQTLSAGHHEISFEIDETLTVTGAETE
IFSALGNLVTNAVRYTPEGGKIRVSWRRDGAQAVFSVKDSGFGIPAEDLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDGQLLIQSEEGRGSTFTARFPAQRTIRRQHAA

Sequences:

>Translated_436_residues
MNIIWVRFLVSLVLLALAAILAGVTIGLRAGLTVGVVLLVAQAFFTTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAELHFGLDAKRDLRQHITHLVRHPDFVRYLNSQH
YDEMVVMRGMGEGRQHVIAVQVFPYGDNRKLLLTQDITEVERTDAMRRDFVANVSHELKTPLTVLSGFLETLRELPLSDD
ERARYLDMMEQQASRMRKIVTDLLVLAKLEGEGKPPTDKPVDMDDVLGHLEDVAQTLSAGHHEISFEIDETLTVTGAETE
IFSALGNLVTNAVRYTPEGGKIRVSWRRDGAQAVFSVKDSGFGIPAEDLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDGQLLIQSEEGRGSTFTARFPAQRTIRRQHAA
>Mature_436_residues
MNIIWVRFLVSLVLLALAAILAGVTIGLRAGLTVGVVLLVAQAFFTTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAELHFGLDAKRDLRQHITHLVRHPDFVRYLNSQH
YDEMVVMRGMGEGRQHVIAVQVFPYGDNRKLLLTQDITEVERTDAMRRDFVANVSHELKTPLTVLSGFLETLRELPLSDD
ERARYLDMMEQQASRMRKIVTDLLVLAKLEGEGKPPTDKPVDMDDVLGHLEDVAQTLSAGHHEISFEIDETLTVTGAETE
IFSALGNLVTNAVRYTPEGGKIRVSWRRDGAQAVFSVKDSGFGIPAEDLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDGQLLIQSEEGRGSTFTARFPAQRTIRRQHAA

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=360, Percent_Identity=40.2777777777778, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI145693157, Length=347, Percent_Identity=28.8184438040346, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI48994928, Length=363, Percent_Identity=29.7520661157025, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=30.1115241635688, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=33.7662337662338, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790436, Length=305, Percent_Identity=26.5573770491803, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1789149, Length=333, Percent_Identity=28.8288288288288, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=33.6538461538462, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=30.5309734513274, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788549, Length=394, Percent_Identity=24.1116751269036, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=27.4074074074074, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=26.6949152542373, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=30.2127659574468, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=31.3364055299539, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=27.3127753303965, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=211, Percent_Identity=30.3317535545024, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=29.9107142857143, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=244, Percent_Identity=27.4590163934426, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=25.068870523416, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788279, Length=197, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49187; Mature: 49187

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIWVRFLVSLVLLALAAILAGVTIGLRAGLTVGVVLLVAQAFFTTFHTQRLWRLLDAP
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAELHFGLDAKRDLRQHITHLVRHPDFVRYLNSQHYDEMVVMRGMGEGRQHVIAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCEEEEE
QVFPYGDNRKLLLTQDITEVERTDAMRRDFVANVSHELKTPLTVLSGFLETLRELPLSDD
EEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERARYLDMMEQQASRMRKIVTDLLVLAKLEGEGKPPTDKPVDMDDVLGHLEDVAQTLSAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
HHEISFEIDETLTVTGAETEIFSALGNLVTNAVRYTPEGGKIRVSWRRDGAQAVFSVKDS
CCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCEEEEECCC
GFGIPAEDLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDGQLLIQSEEGRGSTF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEE
TARFPAQRTIRRQHAA
EEECCHHHHHHHHCCC
>Mature Secondary Structure
MNIIWVRFLVSLVLLALAAILAGVTIGLRAGLTVGVVLLVAQAFFTTFHTQRLWRLLDAP
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAELHFGLDAKRDLRQHITHLVRHPDFVRYLNSQHYDEMVVMRGMGEGRQHVIAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCEEEEE
QVFPYGDNRKLLLTQDITEVERTDAMRRDFVANVSHELKTPLTVLSGFLETLRELPLSDD
EEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERARYLDMMEQQASRMRKIVTDLLVLAKLEGEGKPPTDKPVDMDDVLGHLEDVAQTLSAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
HHEISFEIDETLTVTGAETEIFSALGNLVTNAVRYTPEGGKIRVSWRRDGAQAVFSVKDS
CCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCEEEEECCC
GFGIPAEDLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDGQLLIQSEEGRGSTF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEE
TARFPAQRTIRRQHAA
EEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]