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The map label for this gene is ppx [H]

Identifier: 238026795

GI number: 238026795

Start: 1266802

End: 1268316

Strand: Direct

Name: ppx [H]

Synonym: bglu_1g11530

Alternate gene names: 238026795

Gene position: 1266802-1268316 (Clockwise)

Preceding gene: 238026793

Following gene: 238026801

Centisome position: 32.43

GC content: 68.65

Gene sequence:

>1515_bases
ATGGTTACTTCCCCGCAACTACTCGCCGCCGTCGATCTCGGCTCGAACAGCTTCAGGCTGATCGTCGGACGCGTCGAGGA
AACTCCCGCGGGCAGCCAGATCTACCCGGTCGATGCATTGCGCGAGCCGGTGCGCCTCGCGGCGGGCCTGTCGCGAGACA
AGATGCTCGATCGCGCGTCGCAGGAGCGCGGCTGGGAGGCGCTCAAGCGCTTCGGCGAGCGCCTGCGCGACTTCCATCCC
GACCACGTGCGCGCGGTCGCCACCAACACGCTGCGCGTGGCCAAGAACGCCGGCGAATTCCTGGTCGAGGCGCAGGCCGC
GCTCGGCTTTCCGATCGAGGTGATCGCCGGCCGCGAGGAAGCCCGGCTGATCTACGCGGGCGCGGCGCACTCGGTGCCGG
CCAGTGCCGGCAAGCGGCTCGTGGTCGACATCGGCGGCGGTTCGACCGAGTTCATCATCGGCCAGCACTACACGCCGATC
GTAATGGAAAGCCTCTACATCGGCTGCGTGAGCCACAGCCGCCAGTTCTTCCCGGCCGGCAACGTCGACGAATACACGAT
GCGCCAGGCCGAACTCGCGGCCAAGCGCGAGATCCAGATCATTTCCGGCGAGTACAAGAAAGCGGGCTGGGACCAGGCGA
TCGGCTCGTCGGGCACGGCGCGGGCGCTGGCCGAACTGGTCGAGGGCAACGGCTTCAACGACGCCGGCATCACGCACGGC
ATCTCGCGCGGCGGCCTGGAGCGCCTGAAGCGCGCGCTGATCAAGGCCGAGAACGTGAATCGTCTCAAGCTCGTGGCGCT
GAAGCCGGACCGCATTCCGGTGCTGGCGGGCGGCCTGTCGATCATGCTGGCCGTGTTCGAGGAGCTCGGCGTCGACTATG
TCGACACCACCGACGGCGCGCTGCGCCTGGGCGTGCTGTACGACCTGCTCGGCCGCGCCCAGCACGAGGACATGCGCGCC
GTGACGGTGGAGGGCTTCATGCGCCGCTACGGCGTGGACCGCCCGCAGGCCGACCGGATCGCCTCGCTCGCCACCCGCTT
CTACGACCAGCTCGAATTCACCGACGAGGCGCACCGCGACGAGGATCGGACCTTCGTGGGCTGGGCCGCCGCGCTGCACG
AGATCGGCCTGTCGATCTCGCACAGCGCCTATCACAAGCATTCGGCCTACATCACCAGCAACGCCGACATGCCCGGCTTC
TCGCGCACCGACCAGGCGCGGCTCGCCGCGCTGGTGCTCGGCCACGCGGGCAAGCTCGGCAAGCTCTCGCAATCGCGCGA
CGTGGAATGGCCGCTGCTGTTCTGCCTGCGGCTCGCGGCGCTGCTGTGCCGCCGGCGCACCGATGCCGGGCTGCCGGAAC
TCACGGTGTCGCACGTGAAGAAGGGCGGCTACGAAGTCCGGCTGCCGAGCAGCTGGGTCGAGCAGAACCCGCTGACCGAC
TACAGCCTGAGCCAGGAGGCGGCCGAGTGGGAGAAGGTCGGGATTCCGTATCGCGTCATCTATACCGAGGCCTGA

Upstream 100 bases:

>100_bases
CACCGCGGCGGCGACAGCGCTTAAAATGTTGCGTTTGAATGAGATGGGTCGGCACAGCGGCGGCTCGCCGGCTCGAAGAG
ACACGGAGCCCTTACCCGAT

Downstream 100 bases:

>100_bases
GCCGCCGCGCGCGCCTGCCGGTTCGCTCGCACGCGCCGGGGGCGGCCGCGGGCCCGGGCCGCGGCGGCATCACGGGGTGC
AGACGATCGCCGTGAGGAAC

Product: Exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MVTSPQLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSRDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAGEFLVEAQAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGQHYTPI
VMESLYIGCVSHSRQFFPAGNVDEYTMRQAELAAKREIQIISGEYKKAGWDQAIGSSGTARALAELVEGNGFNDAGITHG
ISRGGLERLKRALIKAENVNRLKLVALKPDRIPVLAGGLSIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRAQHEDMRA
VTVEGFMRRYGVDRPQADRIASLATRFYDQLEFTDEAHRDEDRTFVGWAAALHEIGLSISHSAYHKHSAYITSNADMPGF
SRTDQARLAALVLGHAGKLGKLSQSRDVEWPLLFCLRLAALLCRRRTDAGLPELTVSHVKKGGYEVRLPSSWVEQNPLTD
YSLSQEAAEWEKVGIPYRVIYTEA

Sequences:

>Translated_504_residues
MVTSPQLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSRDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAGEFLVEAQAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGQHYTPI
VMESLYIGCVSHSRQFFPAGNVDEYTMRQAELAAKREIQIISGEYKKAGWDQAIGSSGTARALAELVEGNGFNDAGITHG
ISRGGLERLKRALIKAENVNRLKLVALKPDRIPVLAGGLSIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRAQHEDMRA
VTVEGFMRRYGVDRPQADRIASLATRFYDQLEFTDEAHRDEDRTFVGWAAALHEIGLSISHSAYHKHSAYITSNADMPGF
SRTDQARLAALVLGHAGKLGKLSQSRDVEWPLLFCLRLAALLCRRRTDAGLPELTVSHVKKGGYEVRLPSSWVEQNPLTD
YSLSQEAAEWEKVGIPYRVIYTEA
>Mature_504_residues
MVTSPQLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSRDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAGEFLVEAQAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGQHYTPI
VMESLYIGCVSHSRQFFPAGNVDEYTMRQAELAAKREIQIISGEYKKAGWDQAIGSSGTARALAELVEGNGFNDAGITHG
ISRGGLERLKRALIKAENVNRLKLVALKPDRIPVLAGGLSIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRAQHEDMRA
VTVEGFMRRYGVDRPQADRIASLATRFYDQLEFTDEAHRDEDRTFVGWAAALHEIGLSISHSAYHKHSAYITSNADMPGF
SRTDQARLAALVLGHAGKLGKLSQSRDVEWPLLFCLRLAALLCRRRTDAGLPELTVSHVKKGGYEVRLPSSWVEQNPLTD
YSLSQEAAEWEKVGIPYRVIYTEA

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=497, Percent_Identity=38.0281690140845, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI48994966, Length=498, Percent_Identity=37.5502008032129, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 55362; Mature: 55362

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSPQLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSRDKMLDRAS
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHH
QERGWEALKRFGERLRDFHPDHVRAVATNTLRVAKNAGEFLVEAQAALGFPIEVIAGREE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCEEEECCCCC
ARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGQHYTPIVMESLYIGCVSHSRQFFPAG
CEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
NVDEYTMRQAELAAKREIQIISGEYKKAGWDQAIGSSGTARALAELVEGNGFNDAGITHG
CCCHHHHHHHHHHHHHCEEEECCCCHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCHHCC
ISRGGLERLKRALIKAENVNRLKLVALKPDRIPVLAGGLSIMLAVFEELGVDYVDTTDGA
CCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCH
LRLGVLYDLLGRAQHEDMRAVTVEGFMRRYGVDRPQADRIASLATRFYDQLEFTDEAHRD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHCCC
EDRTFVGWAAALHEIGLSISHSAYHKHSAYITSNADMPGFSRTDQARLAALVLGHAGKLG
CCCCHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KLSQSRDVEWPLLFCLRLAALLCRRRTDAGLPELTVSHVKKGGYEVRLPSSWVEQNPLTD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHCCCCCC
YSLSQEAAEWEKVGIPYRVIYTEA
CCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MVTSPQLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSRDKMLDRAS
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHH
QERGWEALKRFGERLRDFHPDHVRAVATNTLRVAKNAGEFLVEAQAALGFPIEVIAGREE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCEEEECCCCC
ARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGQHYTPIVMESLYIGCVSHSRQFFPAG
CEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
NVDEYTMRQAELAAKREIQIISGEYKKAGWDQAIGSSGTARALAELVEGNGFNDAGITHG
CCCHHHHHHHHHHHHHCEEEECCCCHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCHHCC
ISRGGLERLKRALIKAENVNRLKLVALKPDRIPVLAGGLSIMLAVFEELGVDYVDTTDGA
CCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCH
LRLGVLYDLLGRAQHEDMRAVTVEGFMRRYGVDRPQADRIASLATRFYDQLEFTDEAHRD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHCCC
EDRTFVGWAAALHEIGLSISHSAYHKHSAYITSNADMPGFSRTDQARLAALVLGHAGKLG
CCCCHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KLSQSRDVEWPLLFCLRLAALLCRRRTDAGLPELTVSHVKKGGYEVRLPSSWVEQNPLTD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHCCCCCC
YSLSQEAAEWEKVGIPYRVIYTEA
CCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]