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The map label for this gene is nqo13 [H]

Identifier: 339717977

GI number: 339717977

Start: 2148710

End: 2150263

Strand: Reverse

Name: nqo13 [H]

Synonym: NA

Alternate gene names: 339717977

Gene position: 2150263-2148710 (Counterclockwise)

Preceding gene: 238025058

Following gene: 238025056

Centisome position: 76.05

GC content: 65.96

Gene sequence:

>1554_bases
ATGCAATCTGTACCATTCCTGAGCCTCGCGATCTGGACGCCGATCGTGTTCGGCGTGGCCGTCCTGCGCATCGGTTCGGA
TCGTTATCCGCACCGGGCTCGGTGGCTCGCGCTGGTGGGCGCGATCGTCGGCCTGCTGCTCACCGTGCCGCTCGTCGCCG
GCTTCGACGCGCACAACACGGCGGTGCAGTTCACCGAATACAAGCCGTGGCTCTCGGCTTTCGGTTCGGCATGGCGGATG
GGCGTGGATGGGCTGTCGCTGTGGCTGGTGGTGCTGTCGGCGTTTACGACGCTGGTGATCGTGATCGCCTCGTGGGAATC
GGTCACGACGCGCGTGGCGCAATACCACGGCTCGTTCCTGATCCTGTCGGGGCTGATGATCGGCGTGTTCACCTCGCTCG
ACGGGATGCTGTTCTTCATCTTCTTCGAAGCCACGCTGATCCCGCTGTTCGTGCTGATCGGCACCTGGGGCCACGCGAAC
CGCTCGTATGCGGCGATCAAGTTCTTCTTCATCTCGTTCGCCGGCTCGCTGCTGATGCTGGCCGCGATGCTGTACCTGTT
CGGCCTGACCCACACCTTCGACATGGCGGTCTGGCAGCAGGCCCGGCTGGGCTTCGCGCCGCAGCTGCTGGTGTTCCTCG
GCTTCTTCGCGGCGTTCGCGGTCAAGGTGCCGATGTGGCCGGTCCACACCTGGCTGCAGGACGTGTACACCGACGGCCCG
ACCGGCGCCGCGGTGTCGCTGGGGATGATCAAGATCGGCGGCTACGGCTTCCTGCGCTTCGCGCTGCCGATCGCGCCCGA
CGCGGCCCACTACCTGGCGCCCGTGATGATCGGCCTGTCGCTGGTCGCGGTGGTCTACGCCAGCCTGCTGGCACTGGCGC
AGAAGGACATGGCCAAGATGCTGGCCTATTCGTCGGTCGCGCATATGGGCCTCGTCACGCTCGGCGTGTTCCTGTTCGAC
CAGATGAGCATCACCGGCGCGATCGTGCAGATGATCTCCTACGGTTTCGTGGCCGGCGCGATGTTCCTCTGCGTTGGCGC
GCTCTACGATCGCACCCGCACCCGCGCAATCGCCGAATACAGCGGCGTGGCCAACACCATGCCGCGCCTCGCGCTGTTCG
CCGTGCTGTTCTCGATGGCCAACGTCGGCCTGCCGGGTACCTCGGGCTTCGTCGGCGAATTCCTCGTGATCATGGGCGCC
GTGCGCGTGAACTTCTGGATCGGCGCGATCGCCGCGCTGACCCTGATCCTGAGCGCCGCCTACACGCTGTGGATGCTCAA
GCGCGTGATCTTCGGCGCGATCAAGCACGATCGCGTCGGCAAGCTGATCGATCTGAGCCGGCGCGAGTCGGTGGTATTCG
CGGCGCTGGCCGTGATCGTGCTTGCAATCGGTATTTATCCGAAGCCGTTTACCGACGTGATCGACCCGGCCGCCGCCAGT
ATCGTCGCTCAGCTCGAGCGCGCGAAGCCGGCGGAGGATGGGGCGGGCGCCGCGCCGACGGCTTCCACGATCAGCGTTCA
GAGCGATGCGCGCATCCCGCGCACCCCGACCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Proton-translocating NADH-quinone oxidoreductase, chain M

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 13; NDH-1, chain 13 [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:
NA

Sequences:

>Translated_517_residues
MQSVPFLSLAIWTPIVFGVAVLRIGSDRYPHRARWLALVGAIVGLLLTVPLVAGFDAHNTAVQFTEYKPWLSAFGSAWRM
GVDGLSLWLVVLSAFTTLVIVIASWESVTTRVAQYHGSFLILSGLMIGVFTSLDGMLFFIFFEATLIPLFVLIGTWGHAN
RSYAAIKFFFISFAGSLLMLAAMLYLFGLTHTFDMAVWQQARLGFAPQLLVFLGFFAAFAVKVPMWPVHTWLQDVYTDGP
TGAAVSLGMIKIGGYGFLRFALPIAPDAAHYLAPVMIGLSLVAVVYASLLALAQKDMAKMLAYSSVAHMGLVTLGVFLFD
QMSITGAIVQMISYGFVAGAMFLCVGALYDRTRTRAIAEYSGVANTMPRLALFAVLFSMANVGLPGTSGFVGEFLVIMGA
VRVNFWIGAIAALTLILSAAYTLWMLKRVIFGAIKHDRVGKLIDLSRRESVVFAALAVIVLAIGIYPKPFTDVIDPAAAS
IVAQLERAKPAEDGAGAAPTASTISVQSDARIPRTPT
>Mature_517_residues
MQSVPFLSLAIWTPIVFGVAVLRIGSDRYPHRARWLALVGAIVGLLLTVPLVAGFDAHNTAVQFTEYKPWLSAFGSAWRM
GVDGLSLWLVVLSAFTTLVIVIASWESVTTRVAQYHGSFLILSGLMIGVFTSLDGMLFFIFFEATLIPLFVLIGTWGHAN
RSYAAIKFFFISFAGSLLMLAAMLYLFGLTHTFDMAVWQQARLGFAPQLLVFLGFFAAFAVKVPMWPVHTWLQDVYTDGP
TGAAVSLGMIKIGGYGFLRFALPIAPDAAHYLAPVMIGLSLVAVVYASLLALAQKDMAKMLAYSSVAHMGLVTLGVFLFD
QMSITGAIVQMISYGFVAGAMFLCVGALYDRTRTRAIAEYSGVANTMPRLALFAVLFSMANVGLPGTSGFVGEFLVIMGA
VRVNFWIGAIAALTLILSAAYTLWMLKRVIFGAIKHDRVGKLIDLSRRESVVFAALAVIVLAIGIYPKPFTDVIDPAAAS
IVAQLERAKPAEDGAGAAPTASTISVQSDARIPRTPT

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Homo sapiens, GI251831116, Length=359, Percent_Identity=28.9693593314763, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI251831117, Length=348, Percent_Identity=24.7126436781609, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788613, Length=499, Percent_Identity=33.8677354709419, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1788829, Length=398, Percent_Identity=26.6331658291457, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788827, Length=284, Percent_Identity=25, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693160, Length=419, Percent_Identity=24.582338902148, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788831, Length=409, Percent_Identity=24.4498777506112, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- InterPro:   IPR000260 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01059 Oxidored_q5_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55727; Mature: 55727

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]