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The map label for this gene is fadH [H]

Identifier: 238025058

GI number: 238025058

Start: 2150852

End: 2152885

Strand: Reverse

Name: fadH [H]

Synonym: bglu_2g17140

Alternate gene names: 238025058

Gene position: 2152885-2150852 (Counterclockwise)

Preceding gene: 238025060

Following gene: 339717977

Centisome position: 76.15

GC content: 71.78

Gene sequence:

>2034_bases
ATGACGACCTCGTTTCCGCATCTGCTCGCGCCGCTCGATCTCGGCTTCACAACGCTGCGCAACCGCGTACTCATGGGCTC
CATGCATACCGGCCTCGAGGACAGCCGCAAGACGCTGCCGCGGCTCGCCGACTATTTCGCCGAACGCGCGCGCGGCGGCG
TCGGGCTGATCGTTACCGGCGGCTTCGCGCCGAACCTGGCCGGCTGGACCAAGCCGTTCGGCGGCACGCTGGCGAGCCAC
GCTGCCGCGCGCCGCCATCGCGCGATTGCCGACGCGGTCCACGCCGAAGGCGGCAAGATCGCGCTGCAGATCCTCCATAC
CGGCCGCTACGGCTATCACCCGCTCGCGGTCGCGCCGTCGCGCATCAAGTCGCCGATCTCGCCGTTTACGCCGCGCGCGC
TGTCGGCGGCCGGCGTCGAACGGCAGATCCGGGCGTTCGTGCGCTGCGCGGTGCTGGCGCGCGAGGCCGGCTACGACGGG
GTCGAGATCATGGGTTCCGAGGGCTACCTGATCAACCAGTTCCTCTCGCTGCGCACCAACCGGCGCGACGACGCCTGGGG
CGGCAGCTACCAGAACCGCATGCGCTTTCCGGTGGAGATCGTCGCGCGCACGCGCGAGGCGGTCGGCCGCGACTTCATCA
TCATCTACCGGCTGTCGATGCTGGACCTGATCCCGGACGGCAGCGACTGGGACGAGACGGTGCGGCTCGCCAAGGCCGTG
GAGCGCGCCGGCGCGACGCTGATCAACACCGGCATCGGCTGGCACGAGGCGCGCGTGCCGACTATCGCCACCTCGGTGCC
GCGCGGGGCGTTCGCCTGGATCACGCGCAAGATGAAGGGCGAGGTCGGCATCGCGCTGGTGACCACCAATCGCATCAACC
GGCCGGAGCTGGCCGAGCAGATCCTCGCGGACGGGGCGGCCGACATGGTGTCGATGGCGCGGCCGTTGCTGGCCGATCCG
GAGTTCGTGAGCAAGGCCGCGAGCGGACGCGCCGACGAGATCAACGTCTGCATCGGCTGCAACCAGGCCTGCCTCGACCA
CGCGTTCAAGAACCGCATCGCCTCCTGCCTCGTCAATCCGCGCGCCTGCCACGAGACGCTGCTGAACTTCGCGCCGGCGG
CGCGCGCGAAGCGCATCGCGGTGGTGGGCGCAGGGCCGGCCGGGCTTTCCTGCGCGACGCAGCTGGCGCGGCGTGGGCAC
CGCGTCGAGCTGTTCGACGCGGCCGGCGAGATCGGTGGCCAGTTCAATCTGGCCAAGCGGATTCCCGGCAAGGAGGAATT
CCACGAAACGCTGCGCTACTTCGCGCGGCAGATCGAGCTGACCGGCGTGACGCTGCGGCTGGCGCGGCGCGTGGATGCCG
ACCAACTGATCGCGGGCGGCTACGACGAGGTCGTGCTGGCCACCGGCGTGGTGCCACGCGATCCGCGCATCGCCGGCGGC
GACGGCCCGAACGTGCTCGGCTATGCCGACGTGCTGAGCGGCCGGCGGCCGGTGGGCGCGCGCGTCGCGGTGGTGGGGGC
GGGCGGGATTGGCTTCGACGTGGCCGAGTACCTGGTCCACGCGGGCACCTCGCCGTCGCTCGACGCGGCAGCGTGGCGGG
CCGAGTGGGGCGTCACCGACCCGGCGCTCGCGCGCGGCGGCATCGCGCCGGCGCGGGTGACGCCGCCGGCGCGGCAGGTG
ACGCTGCTGCAGCGCAAGCCGGCGCCGCTCGGCAAGGGGCTCGGCAAAACCACCGGCTGGATTCATCGCGCGACGCTGAA
GATGAAGGCGGTGGAGATGATCGGCGGCGTCAACTACGAACGCATCGATGCGCGCGGCCTGCATGTGACGTTCGGCGAGA
AGCGGGAGCGGCCGACGCTGATCGAGGCCGACACGATCGTGCTGTGTGCCGGGCAGGAGCCGCGCCGCGACCTCGAGGCG
CCGCTCCGCGCGGCCGGCCTCGCCGTGCATCTGATCGGCGGTGCCGAGCTGGCGGCCGAACTCGACGCGAAACGCGCGAT
CGACCAGGGTGCCCGGCTTGCCGCGCGGCTCTGA

Upstream 100 bases:

>100_bases
TTGGCCACGAATGACAAGCATTATGGCTGTTTGACCCCTCACGCTCAAGGCGCCGCGCGCCTACGATCGGCGGATCACAA
AAAAGAGACGCCCCGCCATC

Downstream 100 bases:

>100_bases
GCGGCATGCCGGCGGCCGGGGCCGGGCACCGCCGGCATGCCAGCGAAGCGCGGCTCACTGCAGGCCCGACGGGTCGCATG
GGCGGTTTTCGCTCGCACGA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MTTSFPHLLAPLDLGFTTLRNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNLAGWTKPFGGTLASH
AAARRHRAIADAVHAEGGKIALQILHTGRYGYHPLAVAPSRIKSPISPFTPRALSAAGVERQIRAFVRCAVLAREAGYDG
VEIMGSEGYLINQFLSLRTNRRDDAWGGSYQNRMRFPVEIVARTREAVGRDFIIIYRLSMLDLIPDGSDWDETVRLAKAV
ERAGATLINTGIGWHEARVPTIATSVPRGAFAWITRKMKGEVGIALVTTNRINRPELAEQILADGAADMVSMARPLLADP
EFVSKAASGRADEINVCIGCNQACLDHAFKNRIASCLVNPRACHETLLNFAPAARAKRIAVVGAGPAGLSCATQLARRGH
RVELFDAAGEIGGQFNLAKRIPGKEEFHETLRYFARQIELTGVTLRLARRVDADQLIAGGYDEVVLATGVVPRDPRIAGG
DGPNVLGYADVLSGRRPVGARVAVVGAGGIGFDVAEYLVHAGTSPSLDAAAWRAEWGVTDPALARGGIAPARVTPPARQV
TLLQRKPAPLGKGLGKTTGWIHRATLKMKAVEMIGGVNYERIDARGLHVTFGEKRERPTLIEADTIVLCAGQEPRRDLEA
PLRAAGLAVHLIGGAELAAELDAKRAIDQGARLAARL

Sequences:

>Translated_677_residues
MTTSFPHLLAPLDLGFTTLRNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNLAGWTKPFGGTLASH
AAARRHRAIADAVHAEGGKIALQILHTGRYGYHPLAVAPSRIKSPISPFTPRALSAAGVERQIRAFVRCAVLAREAGYDG
VEIMGSEGYLINQFLSLRTNRRDDAWGGSYQNRMRFPVEIVARTREAVGRDFIIIYRLSMLDLIPDGSDWDETVRLAKAV
ERAGATLINTGIGWHEARVPTIATSVPRGAFAWITRKMKGEVGIALVTTNRINRPELAEQILADGAADMVSMARPLLADP
EFVSKAASGRADEINVCIGCNQACLDHAFKNRIASCLVNPRACHETLLNFAPAARAKRIAVVGAGPAGLSCATQLARRGH
RVELFDAAGEIGGQFNLAKRIPGKEEFHETLRYFARQIELTGVTLRLARRVDADQLIAGGYDEVVLATGVVPRDPRIAGG
DGPNVLGYADVLSGRRPVGARVAVVGAGGIGFDVAEYLVHAGTSPSLDAAAWRAEWGVTDPALARGGIAPARVTPPARQV
TLLQRKPAPLGKGLGKTTGWIHRATLKMKAVEMIGGVNYERIDARGLHVTFGEKRERPTLIEADTIVLCAGQEPRRDLEA
PLRAAGLAVHLIGGAELAAELDAKRAIDQGARLAARL
>Mature_676_residues
TTSFPHLLAPLDLGFTTLRNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTGGFAPNLAGWTKPFGGTLASHA
AARRHRAIADAVHAEGGKIALQILHTGRYGYHPLAVAPSRIKSPISPFTPRALSAAGVERQIRAFVRCAVLAREAGYDGV
EIMGSEGYLINQFLSLRTNRRDDAWGGSYQNRMRFPVEIVARTREAVGRDFIIIYRLSMLDLIPDGSDWDETVRLAKAVE
RAGATLINTGIGWHEARVPTIATSVPRGAFAWITRKMKGEVGIALVTTNRINRPELAEQILADGAADMVSMARPLLADPE
FVSKAASGRADEINVCIGCNQACLDHAFKNRIASCLVNPRACHETLLNFAPAARAKRIAVVGAGPAGLSCATQLARRGHR
VELFDAAGEIGGQFNLAKRIPGKEEFHETLRYFARQIELTGVTLRLARRVDADQLIAGGYDEVVLATGVVPRDPRIAGGD
GPNVLGYADVLSGRRPVGARVAVVGAGGIGFDVAEYLVHAGTSPSLDAAAWRAEWGVTDPALARGGIAPARVTPPARQVT
LLQRKPAPLGKGLGKTTGWIHRATLKMKAVEMIGGVNYERIDARGLHVTFGEKRERPTLIEADTIVLCAGQEPRRDLEAP
LRAAGLAVHLIGGAELAAELDAKRAIDQGARLAARL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=676, Percent_Identity=60.9467455621302, Blast_Score=827, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=346, Percent_Identity=28.9017341040462, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=316, Percent_Identity=24.3670886075949, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=303, Percent_Identity=26.0726072607261, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564188, Length=323, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=254, Percent_Identity=24.4094488188976, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559804, Length=322, Percent_Identity=22.6708074534161, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17566914, Length=316, Percent_Identity=24.6835443037975, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72001454, Length=270, Percent_Identity=25.5555555555556, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321973, Length=229, Percent_Identity=27.0742358078603, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=224, Percent_Identity=26.3392857142857, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72578; Mature: 72447

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSFPHLLAPLDLGFTTLRNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTG
CCCCCCHHHHHHHCCHHHHHHHHEECHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
GFAPNLAGWTKPFGGTLASHAAARRHRAIADAVHAEGGKIALQILHTGRYGYHPLAVAPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEECHH
RIKSPISPFTPRALSAAGVERQIRAFVRCAVLAREAGYDGVEIMGSEGYLINQFLSLRTN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
RRDDAWGGSYQNRMRFPVEIVARTREAVGRDFIIIYRLSMLDLIPDGSDWDETVRLAKAV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHH
ERAGATLINTGIGWHEARVPTIATSVPRGAFAWITRKMKGEVGIALVTTNRINRPELAEQ
HHCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
ILADGAADMVSMARPLLADPEFVSKAASGRADEINVCIGCNQACLDHAFKNRIASCLVNP
HHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCH
RACHETLLNFAPAARAKRIAVVGAGPAGLSCATQLARRGHRVELFDAAGEIGGQFNLAKR
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHCCCCEEHHHC
IPGKEEFHETLRYFARQIELTGVTLRLARRVDADQLIAGGYDEVVLATGVVPRDPRIAGG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCCCCCCCC
DGPNVLGYADVLSGRRPVGARVAVVGAGGIGFDVAEYLVHAGTSPSLDAAAWRAEWGVTD
CCCCCEEHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCC
PALARGGIAPARVTPPARQVTLLQRKPAPLGKGLGKTTGWIHRATLKMKAVEMIGGVNYE
HHHHHCCCCCCCCCCCHHHEEEHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEE
RIDARGLHVTFGEKRERPTLIEADTIVLCAGQEPRRDLEAPLRAAGLAVHLIGGAELAAE
EECCCCEEEEECCCCCCCCEEECCEEEEECCCCCHHHHHHHHHHCCEEEEEECCHHHHHH
LDAKRAIDQGARLAARL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTSFPHLLAPLDLGFTTLRNRVLMGSMHTGLEDSRKTLPRLADYFAERARGGVGLIVTG
CCCCCHHHHHHHCCHHHHHHHHEECHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
GFAPNLAGWTKPFGGTLASHAAARRHRAIADAVHAEGGKIALQILHTGRYGYHPLAVAPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEECHH
RIKSPISPFTPRALSAAGVERQIRAFVRCAVLAREAGYDGVEIMGSEGYLINQFLSLRTN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
RRDDAWGGSYQNRMRFPVEIVARTREAVGRDFIIIYRLSMLDLIPDGSDWDETVRLAKAV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHH
ERAGATLINTGIGWHEARVPTIATSVPRGAFAWITRKMKGEVGIALVTTNRINRPELAEQ
HHCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
ILADGAADMVSMARPLLADPEFVSKAASGRADEINVCIGCNQACLDHAFKNRIASCLVNP
HHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCH
RACHETLLNFAPAARAKRIAVVGAGPAGLSCATQLARRGHRVELFDAAGEIGGQFNLAKR
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHCCCCEEHHHC
IPGKEEFHETLRYFARQIELTGVTLRLARRVDADQLIAGGYDEVVLATGVVPRDPRIAGG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCCCCCCCC
DGPNVLGYADVLSGRRPVGARVAVVGAGGIGFDVAEYLVHAGTSPSLDAAAWRAEWGVTD
CCCCCEEHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCC
PALARGGIAPARVTPPARQVTLLQRKPAPLGKGLGKTTGWIHRATLKMKAVEMIGGVNYE
HHHHHCCCCCCCCCCCHHHEEEHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEE
RIDARGLHVTFGEKRERPTLIEADTIVLCAGQEPRRDLEAPLRAAGLAVHLIGGAELAAE
EECCCCEEEEECCCCCCCCEEECCEEEEECCCCCHHHHHHHHHHCCEEEEEECCHHHHHH
LDAKRAIDQGARLAARL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]