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The map label for this gene is atoC [H]

Identifier: 238025418

GI number: 238025418

Start: 2607132

End: 2608535

Strand: Reverse

Name: atoC [H]

Synonym: bglu_2g21070

Alternate gene names: 238025418

Gene position: 2608535-2607132 (Counterclockwise)

Preceding gene: 238025419

Following gene: 238025417

Centisome position: 92.26

GC content: 74.29

Gene sequence:

>1404_bases
ATGGCGACCATACTGATCATCGACGACGACGATGCGTTTCGCGAAGGCCTCGCCGAAACCATCGAGGACCTCGGCCACGT
TCCGCTCGAGGCCGGCTCCGGCGACGAGGCGTTCGCGATGTTGCGGGCCGGCGCCGCGCCCGCCTGCGTGTTCCTCGATT
TCCGGCTGCCCGGCGCGGACGGCCTGGCGGTGCTCGAAGCGCTGCGCGCCATGGACGGCGCCGACCGCGTGCCGGTGGTG
ATGCTGACCGCGCATGCGACGAGCGCCAACACCATCGGCGCCATGCGGCTGGGCGCCTTCGAGCACCTGACCAAGCCGGT
CGGCCGCGCCGAGATCGCCGCGCTGCTCGGCCGCGTGCTCGCCGGGCAGCGCGAGGCGGCCGACGCCGAGGCGCCGTCGG
CCTTCCTCGACGACGCACCGTCCGACGGGCCGCAACTGCTCGGCATCAGCGAGGCCATGCGGGGCGTGCAGAAGCGCCTG
GGGCGTGCCGCGGCGGCCGATTCGACCGTGCTCATCACCGGCGAGACGGGCACCGGCAAGGAGGTGGCCGCCCGCGTGCT
GCACCGCGAGTCGGCGCGCGCCGGCGGCCCGTTCGTCGCCGTCAACTGCGCGGCGATCCCCGAGGCGCTGCTCGAAAGCG
AGCTGTTCGGCCACGACAAGGGGGCGTTCACGGGCGCCCACGCGCCACGGCAGGGGCGCATCGCGCAGGCGCACGGCGGC
ACGCTGTTCCTCGACGAGATCGGCGACATGCCGATTGCGATGCAGGCCAAGCTGCTGCGCGTGCTGCAGGAGCGCCAGGT
CACGCCGCTCGGCGCGGCCCGCCCGATGGCGGTGGACGTGCGCGTGGTGGCGGCCACCCACCGCGACCTGCAGGAGCGCG
TCGCGGCCGGCGCGTTCCGCCAGGACCTGCTGTATCGGCTCGACGTGATCCCGCTGCATATCCCGCCGCTGCGTGAGCGC
GTGGCCGACATCCTGCCGCTCGCGGAGCACTTTCTCGCCGCGCTTGCACCGGCGGCGGCGCGCAAGCGGCTTTCCGTCGA
GGCGCAGCGCCTGCTCGTCACCTTCACCTGGCCCGGCAACGTGCGCGAGCTGGCCAACGCGATCGAGCGCGCCAGCGCGC
TCGCGCCAGGCCCACTGCTCACGCGCGACGACTTCGCGTTCCTTCTCGATGCCGCGGCCGGCGCCGCCGACGCCGACGCC
GACGCGGTGCCGGCCCAGTTCGCCGAGCTGCCGCTCAACGAGGCGCTGGCGCAGCTCGAGCGCGCGCTGATCGTGCGCGC
GCTGGCGTCCAGCAACGGCAACCGCGCCGAAGCGGCGCGCCGGCTCGGCATCAGCCGTCAGTCGCTCTACACCCGGCTGG
CCAGCCTGGGCATCACGTCTGCCGACGCCGAGCCGGGCGCCTGA

Upstream 100 bases:

>100_bases
GCCTCGGCCTCGTCGTCGTGCGGGAAATCGCTGCGGCGCACGGCGGCCGTGCCTGGCTCGCCAGCGACGCGAACCCCACC
TGCTTCGTGATCGAACTGCC

Downstream 100 bases:

>100_bases
CGCGGCGTGCCGGTGTCAAGCATCCGGACGCAGGTGTCCGGTTTGTTTGACACCGGCAGCCCCATGCGCGCGGCGCGCGC
CCCACGCGACGGGGCTCGCG

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MATILIIDDDDAFREGLAETIEDLGHVPLEAGSGDEAFAMLRAGAAPACVFLDFRLPGADGLAVLEALRAMDGADRVPVV
MLTAHATSANTIGAMRLGAFEHLTKPVGRAEIAALLGRVLAGQREAADAEAPSAFLDDAPSDGPQLLGISEAMRGVQKRL
GRAAAADSTVLITGETGTGKEVAARVLHRESARAGGPFVAVNCAAIPEALLESELFGHDKGAFTGAHAPRQGRIAQAHGG
TLFLDEIGDMPIAMQAKLLRVLQERQVTPLGAARPMAVDVRVVAATHRDLQERVAAGAFRQDLLYRLDVIPLHIPPLRER
VADILPLAEHFLAALAPAAARKRLSVEAQRLLVTFTWPGNVRELANAIERASALAPGPLLTRDDFAFLLDAAAGAADADA
DAVPAQFAELPLNEALAQLERALIVRALASSNGNRAEAARRLGISRQSLYTRLASLGITSADAEPGA

Sequences:

>Translated_467_residues
MATILIIDDDDAFREGLAETIEDLGHVPLEAGSGDEAFAMLRAGAAPACVFLDFRLPGADGLAVLEALRAMDGADRVPVV
MLTAHATSANTIGAMRLGAFEHLTKPVGRAEIAALLGRVLAGQREAADAEAPSAFLDDAPSDGPQLLGISEAMRGVQKRL
GRAAAADSTVLITGETGTGKEVAARVLHRESARAGGPFVAVNCAAIPEALLESELFGHDKGAFTGAHAPRQGRIAQAHGG
TLFLDEIGDMPIAMQAKLLRVLQERQVTPLGAARPMAVDVRVVAATHRDLQERVAAGAFRQDLLYRLDVIPLHIPPLRER
VADILPLAEHFLAALAPAAARKRLSVEAQRLLVTFTWPGNVRELANAIERASALAPGPLLTRDDFAFLLDAAAGAADADA
DAVPAQFAELPLNEALAQLERALIVRALASSNGNRAEAARRLGISRQSLYTRLASLGITSADAEPGA
>Mature_466_residues
ATILIIDDDDAFREGLAETIEDLGHVPLEAGSGDEAFAMLRAGAAPACVFLDFRLPGADGLAVLEALRAMDGADRVPVVM
LTAHATSANTIGAMRLGAFEHLTKPVGRAEIAALLGRVLAGQREAADAEAPSAFLDDAPSDGPQLLGISEAMRGVQKRLG
RAAAADSTVLITGETGTGKEVAARVLHRESARAGGPFVAVNCAAIPEALLESELFGHDKGAFTGAHAPRQGRIAQAHGGT
LFLDEIGDMPIAMQAKLLRVLQERQVTPLGAARPMAVDVRVVAATHRDLQERVAAGAFRQDLLYRLDVIPLHIPPLRERV
ADILPLAEHFLAALAPAAARKRLSVEAQRLLVTFTWPGNVRELANAIERASALAPGPLLTRDDFAFLLDAAAGAADADAD
AVPAQFAELPLNEALAQLERALIVRALASSNGNRAEAARRLGISRQSLYTRLASLGITSADAEPGA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=41.1255411255411, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=40.3805496828753, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1790437, Length=453, Percent_Identity=40.3973509933775, Blast_Score=314, Evalue=9e-87,
Organism=Escherichia coli, GI1788905, Length=467, Percent_Identity=38.3297644539615, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87082117, Length=318, Percent_Identity=48.7421383647799, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI1789087, Length=331, Percent_Identity=45.619335347432, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=46.6463414634146, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=41.6666666666667, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=45.6521739130435, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787583, Length=323, Percent_Identity=39.0092879256966, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=313, Percent_Identity=39.297124600639, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=39.2857142857143, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081858, Length=301, Percent_Identity=33.2225913621262, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48958; Mature: 48826

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILIIDDDDAFREGLAETIEDLGHVPLEAGSGDEAFAMLRAGAAPACVFLDFRLPGAD
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCC
GLAVLEALRAMDGADRVPVVMLTAHATSANTIGAMRLGAFEHLTKPVGRAEIAALLGRVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGQREAADAEAPSAFLDDAPSDGPQLLGISEAMRGVQKRLGRAAAADSTVLITGETGTGK
CCCCHHCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
EVAARVLHRESARAGGPFVAVNCAAIPEALLESELFGHDKGAFTGAHAPRQGRIAQAHGG
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPIAMQAKLLRVLQERQVTPLGAARPMAVDVRVVAATHRDLQERVAAGAFR
EEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHH
QDLLYRLDVIPLHIPPLRERVADILPLAEHFLAALAPAAARKRLSVEAQRLLVTFTWPGN
HHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCC
VRELANAIERASALAPGPLLTRDDFAFLLDAAAGAADADADAVPAQFAELPLNEALAQLE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHH
RALIVRALASSNGNRAEAARRLGISRQSLYTRLASLGITSADAEPGA
HHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ATILIIDDDDAFREGLAETIEDLGHVPLEAGSGDEAFAMLRAGAAPACVFLDFRLPGAD
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCC
GLAVLEALRAMDGADRVPVVMLTAHATSANTIGAMRLGAFEHLTKPVGRAEIAALLGRVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGQREAADAEAPSAFLDDAPSDGPQLLGISEAMRGVQKRLGRAAAADSTVLITGETGTGK
CCCCHHCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
EVAARVLHRESARAGGPFVAVNCAAIPEALLESELFGHDKGAFTGAHAPRQGRIAQAHGG
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPIAMQAKLLRVLQERQVTPLGAARPMAVDVRVVAATHRDLQERVAAGAFR
EEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHH
QDLLYRLDVIPLHIPPLRERVADILPLAEHFLAALAPAAARKRLSVEAQRLLVTFTWPGN
HHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCC
VRELANAIERASALAPGPLLTRDDFAFLLDAAAGAADADADAVPAQFAELPLNEALAQLE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHH
RALIVRALASSNGNRAEAARRLGISRQSLYTRLASLGITSADAEPGA
HHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]