| Definition | Burkholderia glumae BGR1 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_012721 |
| Length | 2,827,333 |
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The map label for this gene is phbB [H]
Identifier: 238025353
GI number: 238025353
Start: 2516371
End: 2517120
Strand: Reverse
Name: phbB [H]
Synonym: bglu_2g20290
Alternate gene names: 238025353
Gene position: 2517120-2516371 (Counterclockwise)
Preceding gene: 238025357
Following gene: 238025352
Centisome position: 89.03
GC content: 66.53
Gene sequence:
>750_bases ATGCATGCCAATGGACGTATCGCCTTCGTCACGGGAGGCATGGGCGGGCTGGGCAGCGCGATCAGCCGGAAGCTGTCCGA CGCCGGCTTCACGGTGGCGATGTCGTACTCGACGCGCAACGATCACGTCGCGGCCTGGTTGTGCGCCGAGCGCGACGCGG GGCACGTGTATCGCGCCTTCGAGCTGGACGTCGGCGATTACGACTCCTGCCAGCGCTGCGCGCGGCAGGTGAACGACGCC TATGGACACGTCGACGTGCTGGTCAACAACGCGGGCATCACGCGCGATGCCGTGTTCTCGAAGATGACGAAACCGGAGTG GGACGAGGTGATGCACACCGATCTGGACGGCATCTTCAACGTCACCAAGCCGTTCATCGGATCGATGGTGTCGCGCGGCT TCGGGCGGGTGATCAATGTCGGGTCGGTCAACGGCATGCGCGGCGCCTTCGGCCAGACCAACTATTCGGCGGCCAAGGCC GGCGTGCATGGCTTCACGATGGCGCTGGCGCGCGAGGTGGCCCGGCACGGCGTCACCGTCAATACCGTGTCGCCGGGCTA TCTGGCCACGCATATGGTGGAGGCCATGCCCAAGGAGGTACTGGAGACGCGCGTCCTGCCGCAGATCCCGGTGGGCCGGC TCGGCAAGCCCGAGGAGGTGGCGGCGCTGATCGCGTTCCTGTGCTCGGCCGAGGCGGCCTTCATCACCGGCGCCGAGATC GCCATCAACGGCGGGATGCAGATGCAATGA
Upstream 100 bases:
>100_bases GATGTCCCGGCGCCGCGAAGGGCGCTTGATCACGATCAATGGCGGTAGGCCAACCGGGCCTAGAGTCGGGTTCGGCAGAC ACCACGCGACAGGAGTCGAC
Downstream 100 bases:
>100_bases TGACCGCCGTCGGCTCCGCGCGGCCGCCGGCCGGCGGCGCCATGCGGGACTCGTTCGGGGGCTCGCTGATCCTGGTCGCG CTCGACGGCAGCCCCGGTTC
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MHANGRIAFVTGGMGGLGSAISRKLSDAGFTVAMSYSTRNDHVAAWLCAERDAGHVYRAFELDVGDYDSCQRCARQVNDA YGHVDVLVNNAGITRDAVFSKMTKPEWDEVMHTDLDGIFNVTKPFIGSMVSRGFGRVINVGSVNGMRGAFGQTNYSAAKA GVHGFTMALAREVARHGVTVNTVSPGYLATHMVEAMPKEVLETRVLPQIPVGRLGKPEEVAALIAFLCSAEAAFITGAEI AINGGMQMQ
Sequences:
>Translated_249_residues MHANGRIAFVTGGMGGLGSAISRKLSDAGFTVAMSYSTRNDHVAAWLCAERDAGHVYRAFELDVGDYDSCQRCARQVNDA YGHVDVLVNNAGITRDAVFSKMTKPEWDEVMHTDLDGIFNVTKPFIGSMVSRGFGRVINVGSVNGMRGAFGQTNYSAAKA GVHGFTMALAREVARHGVTVNTVSPGYLATHMVEAMPKEVLETRVLPQIPVGRLGKPEEVAALIAFLCSAEAAFITGAEI AINGGMQMQ >Mature_249_residues MHANGRIAFVTGGMGGLGSAISRKLSDAGFTVAMSYSTRNDHVAAWLCAERDAGHVYRAFELDVGDYDSCQRCARQVNDA YGHVDVLVNNAGITRDAVFSKMTKPEWDEVMHTDLDGIFNVTKPFIGSMVSRGFGRVINVGSVNGMRGAFGQTNYSAAKA GVHGFTMALAREVARHGVTVNTVSPGYLATHMVEAMPKEVLETRVLPQIPVGRLGKPEEVAALIAFLCSAEAAFITGAEI AINGGMQMQ
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=37.1541501976285, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=34.156378600823, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=32.3529411764706, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.9795918367347, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=28.125, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=31.1787072243346, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=27.1604938271605, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=31.6326530612245, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=29.5275590551181, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=28.780487804878, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI66933014, Length=194, Percent_Identity=28.3505154639175, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=28.3400809716599, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=25.4032258064516, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI157739938, Length=194, Percent_Identity=25.7731958762887, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=28.1818181818182, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI150247226, Length=218, Percent_Identity=30.7339449541284, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.4248704663212, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI40548397, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI214010158, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI214010156, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI22758144, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI22507405, Length=212, Percent_Identity=30.188679245283, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI19743808, Length=202, Percent_Identity=30.6930693069307, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=25.7281553398058, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4504503, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=40.4, Blast_Score=189, Evalue=1e-49, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=34.1176470588235, Blast_Score=140, Evalue=6e-35, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.1138211382114, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=29.2181069958848, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.9595141700405, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=26.8595041322314, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.4285714285714, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=32.9317269076305, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.4591439688716, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=23.8866396761134, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=24.21875, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=26.775956284153, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787526, Length=238, Percent_Identity=24.3697478991597, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=39.4308943089431, Blast_Score=170, Evalue=8e-43, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=37.3983739837398, Blast_Score=160, Evalue=5e-40, Organism=Caenorhabditis elegans, GI17568967, Length=233, Percent_Identity=30.4721030042918, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.8943089430894, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=27.734375, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=27.6923076923077, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=28.8537549407115, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=25, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=27.4900398406374, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=30.2788844621514, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI72000259, Length=198, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=26.4925373134328, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=26.0162601626016, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=26.8199233716475, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=27.8810408921933, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.4367816091954, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=24.6073298429319, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17563726, Length=181, Percent_Identity=28.7292817679558, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=26.8199233716475, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=26.1306532663317, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=25.2747252747253, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=23.9852398523985, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=25.5208333333333, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=22.5641025641026, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=32.1888412017167, Blast_Score=115, Evalue=5e-27, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=24.4979919678715, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=34.6774193548387, Blast_Score=148, Evalue=4e-36, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.1269841269841, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=33.0472103004292, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=31.7269076305221, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.1632653061224, Blast_Score=100, Evalue=6e-22, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=30.6201550387597, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.0395256916996, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=26.8595041322314, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=182, Percent_Identity=35.1648351648352, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=28.6458333333333, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=30.0970873786408, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=30.0970873786408, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=28.2352941176471, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=26.063829787234, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24581726, Length=167, Percent_Identity=26.3473053892216, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24640442, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=28.0851063829787, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=25.5208333333333, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26589; Mature: 26589
Theoretical pI: Translated: 6.95; Mature: 6.95
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.8 %Met (Translated Protein) 6.4 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 6.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHANGRIAFVTGGMGGLGSAISRKLSDAGFTVAMSYSTRNDHVAAWLCAERDAGHVYRAF CCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEE ELDVGDYDSCQRCARQVNDAYGHVDVLVNNAGITRDAVFSKMTKPEWDEVMHTDLDGIFN EECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH VTKPFIGSMVSRGFGRVINVGSVNGMRGAFGQTNYSAAKAGVHGFTMALAREVARHGVTV HHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCEE NTVSPGYLATHMVEAMPKEVLETRVLPQIPVGRLGKPEEVAALIAFLCSAEAAFITGAEI EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEECCEE AINGGMQMQ EECCCCCCC >Mature Secondary Structure MHANGRIAFVTGGMGGLGSAISRKLSDAGFTVAMSYSTRNDHVAAWLCAERDAGHVYRAF CCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEE ELDVGDYDSCQRCARQVNDAYGHVDVLVNNAGITRDAVFSKMTKPEWDEVMHTDLDGIFN EECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH VTKPFIGSMVSRGFGRVINVGSVNGMRGAFGQTNYSAAKAGVHGFTMALAREVARHGVTV HHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCEE NTVSPGYLATHMVEAMPKEVLETRVLPQIPVGRLGKPEEVAALIAFLCSAEAAFITGAEI EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEECCEE AINGGMQMQ EECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]