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The map label for this gene is cdd [H]

Identifier: 238025068

GI number: 238025068

Start: 2162287

End: 2162676

Strand: Reverse

Name: cdd [H]

Synonym: bglu_2g17240

Alternate gene names: 238025068

Gene position: 2162676-2162287 (Counterclockwise)

Preceding gene: 238025069

Following gene: 238025064

Centisome position: 76.49

GC content: 73.33

Gene sequence:

>390_bases
ATGGACCACGACACCCTGATCGAAACGGCGCGGCGCGCGCGCGAGCATGCCTACGCCCCGTATTCACGGTTCCAGGTCGG
CGCGGCGGTGACGACGCACGACGGGCGCGTCTTCGCGGGATGCAACGTGGAGAACGGCGCATACGGCCTGAGCAACTGCG
CCGAGCGCACGGCGCTGTTCGCGGCGATCGCGGCCGGCTGCCGGCCTGGCGATTTCGCGGTGCTGGCCGTGATCGGCGAC
ACGCCCGAGCCGATCGCGCCGTGCGGCGCGTGCCGGCAGGTGATGGTCGAACTCGGCGGGCCGGCGCTGTCGGTGGTGCT
GGCCAACCTGCGCGGCGCGCGGCAGGAAACGACCGCGGCGGCGCTGCTGCCGGGGGCGTTCCGTCTCTGA

Upstream 100 bases:

>100_bases
AGGATGCCGGCGGCGCGCAGCGGCCCGCCACCGGCGCGCGCACCCGCGGCGGGGCGGCGCGCCCCGAGATGACACGACAC
GAAGCGGCGAGGAGCAGACG

Downstream 100 bases:

>100_bases
GCGTGCGGCGCGGCGCGCCGGCACGCGTCAGACCTGCACGAGCCGCTGCGCGTCGGTGATGCGGATCTGCCGGCCGCGCG
AGTCGATCATGCCGCTGCGC

Product: Cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MDHDTLIETARRAREHAYAPYSRFQVGAAVTTHDGRVFAGCNVENGAYGLSNCAERTALFAAIAAGCRPGDFAVLAVIGD
TPEPIAPCGACRQVMVELGGPALSVVLANLRGARQETTAAALLPGAFRL

Sequences:

>Translated_129_residues
MDHDTLIETARRAREHAYAPYSRFQVGAAVTTHDGRVFAGCNVENGAYGLSNCAERTALFAAIAAGCRPGDFAVLAVIGD
TPEPIAPCGACRQVMVELGGPALSVVLANLRGARQETTAAALLPGAFRL
>Mature_129_residues
MDHDTLIETARRAREHAYAPYSRFQVGAAVTTHDGRVFAGCNVENGAYGLSNCAERTALFAAIAAGCRPGDFAVLAVIGD
TPEPIAPCGACRQVMVELGGPALSVVLANLRGARQETTAAALLPGAFRL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=123, Percent_Identity=43.9024390243902, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=43.4426229508197, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=41.4634146341463, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323274, Length=126, Percent_Identity=37.3015873015873, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582741, Length=129, Percent_Identity=41.8604651162791, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582744, Length=141, Percent_Identity=38.2978723404255, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920920, Length=138, Percent_Identity=37.6811594202899, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13428; Mature: 13428

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHDTLIETARRAREHAYAPYSRFQVGAAVTTHDGRVFAGCNVENGAYGLSNCAERTALF
CCHHHHHHHHHHHHHHCCCCHHHEEECEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHH
AAIAAGCRPGDFAVLAVIGDTPEPIAPCGACRQVMVELGGPALSVVLANLRGARQETTAA
HHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHH
ALLPGAFRL
HHCCCCCCC
>Mature Secondary Structure
MDHDTLIETARRAREHAYAPYSRFQVGAAVTTHDGRVFAGCNVENGAYGLSNCAERTALF
CCHHHHHHHHHHHHHHCCCCHHHEEECEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHH
AAIAAGCRPGDFAVLAVIGDTPEPIAPCGACRQVMVELGGPALSVVLANLRGARQETTAA
HHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHH
ALLPGAFRL
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]