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The map label for this gene is gbpR [H]

Identifier: 238024827

GI number: 238024827

Start: 1865989

End: 1866957

Strand: Direct

Name: gbpR [H]

Synonym: bglu_2g14670

Alternate gene names: 238024827

Gene position: 1865989-1866957 (Clockwise)

Preceding gene: 238024825

Following gene: 238024829

Centisome position: 66.0

GC content: 70.69

Gene sequence:

>969_bases
GTGGCTTTCGATACGGACGAAGTGATCCGGCGCCTCAGCACTCGTCTGAAGATTCGCCACCTGATCCTGCTGCTGCAGAT
CCGCCAGTTCGGCTCGCTCACGCGCGTGGCCGAGCAGATGGCAAGCAGCCAGCCGGCCGTCACGAACGCGCTGGCCGAAC
TCGAAGCCATGTTCGGCGGCCCGCTGTTCGACCGCACGCCACGCGGCATGACGCCCACCGCGCTCGGCAAGGTGGTGCTG
GCGCGCGCGCAGGCCATGCTGCACGACCTCGAGCACCTCACGCGCGACATCGAGGCGGTGGTGGCGGGCCACGCCACGCG
CATCCACATCGGCGTGATCCCGTTCATCTCGGGCAAGACGCTCGCCGCCGCGATCCGCCGGACCCAGGCCGACGTGCCGC
AGCGGCTCACCATGACGATCCACGAAGGCACCAGCGAGACGCTGATCGCGCAGTTGCGCGAGCACCAGCTCGACGTGGTG
ATCGCGCGCGCCACCTCCACCGTCGATCTGGCCGACCTGCGCTTCGAGGTGGTCTACCAGCAGCGGCCGCGGCTGATCGC
GAGCCGGCGCCTCGCCGCACGGCTCGCGCGCAACGCGCTCGACTGGCAGAAGCTCGTCGAACTCGACTGGATTCTCGGCG
CGCCGCACACGCCGATCCGCGAGCAGATCTCCGACCTGTTCCTGCGCGCCGGCGCCTCGCCGCCGGTGCCGATCGTCGAG
AGCTATTCGTCGCGCCTGATCGGCGAGATCCTCGCCTCGAACGAGAACGCCGTGTCGATCGTGCCGGCCGACATCGCCGA
GGAGCTCGTGCATGTCGCCGGCGTGGCGATCGTGCCGTATTCGCTCGACTGGACGCTGCCGCCGGTGGCGATCCTCACGC
GCGGCGGGCCGCCGCGCGAAGTGGACACGCTGCTCGCGCGCGCGCTGCGGGCGCAGTACCAGGAAGCCGAGGCGCGGCGC
CCGGCCTAG

Upstream 100 bases:

>100_bases
CGGCGATCTGAGGAAGCGATTCTAGGCAGCCGCTAAGGGTGCGCCATTTTGAATTAGTATGGGCGCATCACCTTTTCATG
ATGACCAGGGTTTCGCCACA

Downstream 100 bases:

>100_bases
GCGGCCGGCGCGGGCCGCCCGCCCCGTTGTCCGCCGCCCCTCCACCAATGAAAACGGGCCGCCCGAGGCGGCCCGTCGAA
GGTCGCGGTTCGCGCCGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MAFDTDEVIRRLSTRLKIRHLILLLQIRQFGSLTRVAEQMASSQPAVTNALAELEAMFGGPLFDRTPRGMTPTALGKVVL
ARAQAMLHDLEHLTRDIEAVVAGHATRIHIGVIPFISGKTLAAAIRRTQADVPQRLTMTIHEGTSETLIAQLREHQLDVV
IARATSTVDLADLRFEVVYQQRPRLIASRRLAARLARNALDWQKLVELDWILGAPHTPIREQISDLFLRAGASPPVPIVE
SYSSRLIGEILASNENAVSIVPADIAEELVHVAGVAIVPYSLDWTLPPVAILTRGGPPREVDTLLARALRAQYQEAEARR
PA

Sequences:

>Translated_322_residues
MAFDTDEVIRRLSTRLKIRHLILLLQIRQFGSLTRVAEQMASSQPAVTNALAELEAMFGGPLFDRTPRGMTPTALGKVVL
ARAQAMLHDLEHLTRDIEAVVAGHATRIHIGVIPFISGKTLAAAIRRTQADVPQRLTMTIHEGTSETLIAQLREHQLDVV
IARATSTVDLADLRFEVVYQQRPRLIASRRLAARLARNALDWQKLVELDWILGAPHTPIREQISDLFLRAGASPPVPIVE
SYSSRLIGEILASNENAVSIVPADIAEELVHVAGVAIVPYSLDWTLPPVAILTRGGPPREVDTLLARALRAQYQEAEARR
PA
>Mature_321_residues
AFDTDEVIRRLSTRLKIRHLILLLQIRQFGSLTRVAEQMASSQPAVTNALAELEAMFGGPLFDRTPRGMTPTALGKVVLA
RAQAMLHDLEHLTRDIEAVVAGHATRIHIGVIPFISGKTLAAAIRRTQADVPQRLTMTIHEGTSETLIAQLREHQLDVVI
ARATSTVDLADLRFEVVYQQRPRLIASRRLAARLARNALDWQKLVELDWILGAPHTPIREQISDLFLRAGASPPVPIVES
YSSRLIGEILASNENAVSIVPADIAEELVHVAGVAIVPYSLDWTLPPVAILTRGGPPREVDTLLARALRAQYQEAEARRP
A

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=270, Percent_Identity=24.8148148148148, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789506, Length=249, Percent_Identity=21.6867469879518, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=267, Percent_Identity=23.9700374531835, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=283, Percent_Identity=22.6148409893993, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=274, Percent_Identity=26.6423357664234, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35474; Mature: 35342

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDTDEVIRRLSTRLKIRHLILLLQIRQFGSLTRVAEQMASSQPAVTNALAELEAMFGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PLFDRTPRGMTPTALGKVVLARAQAMLHDLEHLTRDIEAVVAGHATRIHIGVIPFISGKT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHH
LAAAIRRTQADVPQRLTMTIHEGTSETLIAQLREHQLDVVIARATSTVDLADLRFEVVYQ
HHHHHHHHHHCCCHHEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
QRPRLIASRRLAARLARNALDWQKLVELDWILGAPHTPIREQISDLFLRAGASPPVPIVE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
SYSSRLIGEILASNENAVSIVPADIAEELVHVAGVAIVPYSLDWTLPPVAILTRGGPPRE
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCHHEEEEECCCCCCCHHEEECCCCCHH
VDTLLARALRAQYQEAEARRPA
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AFDTDEVIRRLSTRLKIRHLILLLQIRQFGSLTRVAEQMASSQPAVTNALAELEAMFGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PLFDRTPRGMTPTALGKVVLARAQAMLHDLEHLTRDIEAVVAGHATRIHIGVIPFISGKT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHH
LAAAIRRTQADVPQRLTMTIHEGTSETLIAQLREHQLDVVIARATSTVDLADLRFEVVYQ
HHHHHHHHHHCCCHHEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
QRPRLIASRRLAARLARNALDWQKLVELDWILGAPHTPIREQISDLFLRAGASPPVPIVE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
SYSSRLIGEILASNENAVSIVPADIAEELVHVAGVAIVPYSLDWTLPPVAILTRGGPPRE
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCHHEEEEECCCCCCCHHEEECCCCCHH
VDTLLARALRAQYQEAEARRPA
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]