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The map label for this gene is chaA [C]

Identifier: 238024617

GI number: 238024617

Start: 1570159

End: 1571244

Strand: Direct

Name: chaA [C]

Synonym: bglu_2g12320

Alternate gene names: 238024617

Gene position: 1570159-1571244 (Clockwise)

Preceding gene: 238024615

Following gene: 238024619

Centisome position: 55.53

GC content: 71.18

Gene sequence:

>1086_bases
ATGCCGAACTCTTCGCACGCCTTGCCCCGCTGGACGCTCGCCGCCCCGATCGCGGCCTGGCTGGTACTCGCGCTGGCGGG
CTTCATTCCGTTCGCCTGGCTGGCGATCACGCTGATCGCGGCGGCGCTGGCCGGCTCGGTGTTCGCCGCGGTCCATCACG
CCGAGGTGGTCGCGCATCGCGTCGGGGAGCCGTTCGGCACGCTGGTGCTGGCGATCGCGGTGACGGTCATCGAGGTGGCG
CTGATCGTCTCGGTGATGCTGTCGGCCGGCCCCGAGAAATCGGGCCTCGCGCGCGACACGGTGTTCGCGGCGGTGATGAT
CGTCTGCAACGGCATCGTCGGGCTCTGCCTGCTGGTGGGCGGCTGGCAGCACGGCGAGCAGGACTTCCAGGGACGCGGCG
CGAGCAAGTCGCTCGCGGTGCTGGCCTCGCTGTCGGTGCTCTCGCTGGTGATGCCGAACTACCTGAACGCGGCGCCGGGT
CCGCAGTTCTCCACCTCGCAGCTGGCCTTCGCGGGGGTCTCCTCGCTGGTGCTCTACGGCGTGTTCGTGTTCGTGCAGAC
GGTGCGCCACCGCGATTATTTCCTGGTCGCCGAAAGCGCCGACGAGTCGATCCACGCGGCACCGCCCACGGCGCGCGTCG
CGCTGACCAGCGTGGTGTTCCTGCTGATCGCGCTGGTGGCGGTGGTGCTGCTCGCGAAGCTGCTGTCGCCGGCCGTCGAG
CGCGGCGTGCTGCGCCTGGGCGCGCCGGAGGCGGCGGTCGGCATCGTGATCGCGGCGCTGGTGCTGCTGCCCGAAGGGCT
TGCGGCGGTCGGCGCGGCGCGCGCGAACCGCCTGCAGACGAGCCTGAACCTCGCGCTCGGCTCGGCGCTGGCCAGCATCG
GGCTGACCATTCCCACCGTGGCCGCCGTGTTCATCTGGACCGGCCAGCCGCTCACGCTCGGCATCGGCCCGATGGAAACG
GTGCTGCTCGCGCTCACGCTGCTGGTCAGCACGCTGACGCTGAGCGCGGGCCGCACCACGGTGCTGCAGGGCGTGGTCCA
CCTCTCGCTGTTCGCCGCCTACCTGTTCCTGTCGGTCACGCACTGA

Upstream 100 bases:

>100_bases
GGGCCGGAACGCCGCGGCCGCCTGCTAGAATCGGGCACGGGTGAACCCGCCCAGGGACGCCGAGGCCGCCCCCGATCAAC
CAAGCCACCCAGGACCGCCG

Downstream 100 bases:

>100_bases
CGCCGGTGCCGGCCGCGCCTCGGGCCGGCAGGCGATGCGCCGGCCGCCCCGCGGCCTGCGCGGCGCTCAGGCGCCGGCCG
GCACGGTGCCGGCCAGCCGC

Product: Ionic antiporter

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPNSSHALPRWTLAAPIAAWLVLALAGFIPFAWLAITLIAAALAGSVFAAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVA
LIVSVMLSAGPEKSGLARDTVFAAVMIVCNGIVGLCLLVGGWQHGEQDFQGRGASKSLAVLASLSVLSLVMPNYLNAAPG
PQFSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLVAESADESIHAAPPTARVALTSVVFLLIALVAVVLLAKLLSPAVE
RGVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSLNLALGSALASIGLTIPTVAAVFIWTGQPLTLGIGPMET
VLLALTLLVSTLTLSAGRTTVLQGVVHLSLFAAYLFLSVTH

Sequences:

>Translated_361_residues
MPNSSHALPRWTLAAPIAAWLVLALAGFIPFAWLAITLIAAALAGSVFAAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVA
LIVSVMLSAGPEKSGLARDTVFAAVMIVCNGIVGLCLLVGGWQHGEQDFQGRGASKSLAVLASLSVLSLVMPNYLNAAPG
PQFSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLVAESADESIHAAPPTARVALTSVVFLLIALVAVVLLAKLLSPAVE
RGVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSLNLALGSALASIGLTIPTVAAVFIWTGQPLTLGIGPMET
VLLALTLLVSTLTLSAGRTTVLQGVVHLSLFAAYLFLSVTH
>Mature_360_residues
PNSSHALPRWTLAAPIAAWLVLALAGFIPFAWLAITLIAAALAGSVFAAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVAL
IVSVMLSAGPEKSGLARDTVFAAVMIVCNGIVGLCLLVGGWQHGEQDFQGRGASKSLAVLASLSVLSLVMPNYLNAAPGP
QFSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLVAESADESIHAAPPTARVALTSVVFLLIALVAVVLLAKLLSPAVER
GVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSLNLALGSALASIGLTIPTVAAVFIWTGQPLTLGIGPMETV
LLALTLLVSTLTLSAGRTTVLQGVVHLSLFAAYLFLSVTH

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=326, Percent_Identity=37.7300613496933, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37156; Mature: 37025

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSSHALPRWTLAAPIAAWLVLALAGFIPFAWLAITLIAAALAGSVFAAVHHAEVVAHR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKSGLARDTVFAAVMIVCNGIVGLCLLVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GWQHGEQDFQGRGASKSLAVLASLSVLSLVMPNYLNAAPGPQFSTSQLAFAGVSSLVLYG
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VFVFVQTVRHRDYFLVAESADESIHAAPPTARVALTSVVFLLIALVAVVLLAKLLSPAVE
HHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSLNLALGSALASIGLTIPTV
HCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVFIWTGQPLTLGIGPMETVLLALTLLVSTLTLSAGRTTVLQGVVHLSLFAAYLFLSVT
HHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
H
C
>Mature Secondary Structure 
PNSSHALPRWTLAAPIAAWLVLALAGFIPFAWLAITLIAAALAGSVFAAVHHAEVVAHR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKSGLARDTVFAAVMIVCNGIVGLCLLVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GWQHGEQDFQGRGASKSLAVLASLSVLSLVMPNYLNAAPGPQFSTSQLAFAGVSSLVLYG
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VFVFVQTVRHRDYFLVAESADESIHAAPPTARVALTSVVFLLIALVAVVLLAKLLSPAVE
HHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSLNLALGSALASIGLTIPTV
HCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVFIWTGQPLTLGIGPMETVLLALTLLVSTLTLSAGRTTVLQGVVHLSLFAAYLFLSVT
HHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]