Click here to switch to the map view.

The map label for this gene is prsA [H]

Identifier: 229918171

GI number: 229918171

Start: 2408702

End: 2409703

Strand: Reverse

Name: prsA [H]

Synonym: EAT1b_2451

Alternate gene names: 229918171

Gene position: 2409703-2408702 (Counterclockwise)

Preceding gene: 229918173

Following gene: 229918169

Centisome position: 80.33

GC content: 45.21

Gene sequence:

>1002_bases
ATGTCAAACGGAATGACGAACGAACCAAAAAAGCAAGATAAAAAATTCTCAACTGGCGCACTCGTGGGTGCATCTGCAAT
CGCACTCATCATCGGTGCTGGCGGTACGTATGCGGCAACGAACGCAGGCGGCGGAGAGTCAGATAATTCAGCAGTCGTCA
CATATAAAGGCGGCGAAATCACACGCGGTGAAATCGCGGATATGAGCTATGATCGCATGGTGCCACAACTCGCATTCCAA
GAGACGATGAATGCACTTCTTGAAAAAGAATACGGTGACCAAGTCGACCAAGAAAAAGTAGACGAAGAGTTCAGCAAGAC
AGAAGAACAGTTCAACTCAGAAGAAGAATTCGAACAAGCGATTCAACAAGCCGGCATGAGCGGTACGGAAGAGTTCAAAG
AAGCGCTTCGCGGACAGATGCTCGTTGACGCTGCGAAATCGAAACTTGTCGATGTGACCGATGAAGAAATCGAAGCACAG
TTCGCAAAAGAGAACGTGGAAGTGGAAGCTAGCCACATCCTCGTTGAAACTGAAGAAGAGGCACAAGACATCATCAAAGA
GTTGAATGACGGTGCAGACTTCGCTGAACTTGCGAAAGAAAAATCAACGGATACTGGTTCAGGTGAAAAAGGTGGAGAAC
TCGGTTTCTTCTCTGCTGGTGCGATGGTACCTGAATTCGAAGAGTATGCATTCAAAGAAGATGTCGTTGGTAAAATCTCT
GAGCCGGTTCAATCTCAGTTCGGTTTCCATGTCATCAAAGTGACAGACCGTAAAGAGAAAGATTTGAAACTCGAAGACGA
GAAAGATCGCATTCGTGAAGAATTGGCAGCTGAAAAATCAGCTTCTGTCGATGCCAACAAAATTTACGCGGAGTTGATTG
AAAAATACAACGTTGACGTAAAAGATGCAAAAGCAGAACAACAATTTGACGCTGTTAAAGAAGCGATTAAAAACGCAGAC
GAGTCTTCAGAAGAACCTGCAGCAGAATCAACTGAACAGTAA

Upstream 100 bases:

>100_bases
GTGCTATGATACTGTACAGACAAGAGAACAGCTGTCATGATTAGGAAAATGTGATATAGTCGGACTTAGAAACTTTAAAG
AATTATTAGGGGTGGAATAC

Downstream 100 bases:

>100_bases
TCACAAAGGGGCACTCCAGCAATGGAGTACCCCTTTTTCGTTGGTCACCTGTTATAGATTCGGGCGATAGAAGGCACGGT
TATCGAGTGCCATGACACGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSNGMTNEPKKQDKKFSTGALVGASAIALIIGAGGTYAATNAGGGESDNSAVVTYKGGEITRGEIADMSYDRMVPQLAFQ
ETMNALLEKEYGDQVDQEKVDEEFSKTEEQFNSEEEFEQAIQQAGMSGTEEFKEALRGQMLVDAAKSKLVDVTDEEIEAQ
FAKENVEVEASHILVETEEEAQDIIKELNDGADFAELAKEKSTDTGSGEKGGELGFFSAGAMVPEFEEYAFKEDVVGKIS
EPVQSQFGFHVIKVTDRKEKDLKLEDEKDRIREELAAEKSASVDANKIYAELIEKYNVDVKDAKAEQQFDAVKEAIKNAD
ESSEEPAAESTEQ

Sequences:

>Translated_333_residues
MSNGMTNEPKKQDKKFSTGALVGASAIALIIGAGGTYAATNAGGGESDNSAVVTYKGGEITRGEIADMSYDRMVPQLAFQ
ETMNALLEKEYGDQVDQEKVDEEFSKTEEQFNSEEEFEQAIQQAGMSGTEEFKEALRGQMLVDAAKSKLVDVTDEEIEAQ
FAKENVEVEASHILVETEEEAQDIIKELNDGADFAELAKEKSTDTGSGEKGGELGFFSAGAMVPEFEEYAFKEDVVGKIS
EPVQSQFGFHVIKVTDRKEKDLKLEDEKDRIREELAAEKSASVDANKIYAELIEKYNVDVKDAKAEQQFDAVKEAIKNAD
ESSEEPAAESTEQ
>Mature_332_residues
SNGMTNEPKKQDKKFSTGALVGASAIALIIGAGGTYAATNAGGGESDNSAVVTYKGGEITRGEIADMSYDRMVPQLAFQE
TMNALLEKEYGDQVDQEKVDEEFSKTEEQFNSEEEFEQAIQQAGMSGTEEFKEALRGQMLVDAAKSKLVDVTDEEIEAQF
AKENVEVEASHILVETEEEAQDIIKELNDGADFAELAKEKSTDTGSGEKGGELGFFSAGAMVPEFEEYAFKEDVVGKISE
PVQSQFGFHVIKVTDRKEKDLKLEDEKDRIREELAAEKSASVDANKIYAELIEKYNVDVKDAKAEQQFDAVKEAIKNADE
SSEEPAAESTEQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=88, Percent_Identity=44.3181818181818, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786645, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36473; Mature: 36342

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGMTNEPKKQDKKFSTGALVGASAIALIIGAGGTYAATNAGGGESDNSAVVTYKGGEI
CCCCCCCCCHHHHHCHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCEEEEECCCCC
TRGEIADMSYDRMVPQLAFQETMNALLEKEYGDQVDQEKVDEEFSKTEEQFNSEEEFEQA
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
IQQAGMSGTEEFKEALRGQMLVDAAKSKLVDVTDEEIEAQFAKENVEVEASHILVETEEE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEHEEEEECHHH
AQDIIKELNDGADFAELAKEKSTDTGSGEKGGELGFFSAGAMVPEFEEYAFKEDVVGKIS
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EPVQSQFGFHVIKVTDRKEKDLKLEDEKDRIREELAAEKSASVDANKIYAELIEKYNVDV
HHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
KDAKAEQQFDAVKEAIKNADESSEEPAAESTEQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNGMTNEPKKQDKKFSTGALVGASAIALIIGAGGTYAATNAGGGESDNSAVVTYKGGEI
CCCCCCCCHHHHHCHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCEEEEECCCCC
TRGEIADMSYDRMVPQLAFQETMNALLEKEYGDQVDQEKVDEEFSKTEEQFNSEEEFEQA
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
IQQAGMSGTEEFKEALRGQMLVDAAKSKLVDVTDEEIEAQFAKENVEVEASHILVETEEE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEHEEEEECHHH
AQDIIKELNDGADFAELAKEKSTDTGSGEKGGELGFFSAGAMVPEFEEYAFKEDVVGKIS
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EPVQSQFGFHVIKVTDRKEKDLKLEDEKDRIREELAAEKSASVDANKIYAELIEKYNVDV
HHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
KDAKAEQQFDAVKEAIKNADESSEEPAAESTEQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA