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The map label for this gene is yugJ [H]

Identifier: 229917814

GI number: 229917814

Start: 2045898

End: 2047061

Strand: Reverse

Name: yugJ [H]

Synonym: EAT1b_2092

Alternate gene names: 229917814

Gene position: 2047061-2045898 (Counterclockwise)

Preceding gene: 229917815

Following gene: 229917812

Centisome position: 68.24

GC content: 52.49

Gene sequence:

>1164_bases
ATGGAACGTTTTCAATATCATAACCCGACCAAACTCTTATTCGGAAAAGGACAACTAGAATCACTCCGTACCGAAATTCC
ACGATACGGGGACCGCGTCCTTCTCTTATACGGTGGAGGGAGCATCAAAGCGAACGGTCTTTATGAAGAAGTAACCGCTC
TGTTAGCCGATATGCAAGTAACCGTCGTCGAACTTTCTGGCGTCGAACCTAACCCGCGTCTGACGACAGTTCAAACAGGA
ATCGATTTAGTGCATGAACACCAAATCGATCTCATCCTAGCTGTCGGAGGAGGGAGCGTCATCGACTGTGCGAAAGGAAT
CGCAGCCGGTGCCAAATATGACGGGAATCCATGGGACATCGTGACGCGACAAGTCCCCGTCACAGATGCGTTACCGATCG
GGACCGTTTTGACATTGGCGGCAACGGGATCGGAAATGAACGGTGGGGCCGTCATCACGAACTGGGAGGCGCAAGATAAG
CGCTCGTTCGGCTCGCCCCTCACTTACCCGAAATTCAGCGTACTCGACCCGACGTATACGTTAAGTGTACCGGCGAACCA
GACCGTCTACGGAATCGTCGATATCATGTCGCACGTCTTCGAACAATACTTCCACGCTTCAGAGAACGCCCTGCTCCAAG
AGCGGTTCGGTGAATCGATTTTACGCACCATGATGGAGACGGCACCACGTCTCGTTCAAAACTTGAATGATTTTGACGCA
CGGGAAACGATGCTCTTGAACGGAACGTTTGCCTTAAACGGGACATTATCGATGGGCGTGAAGACGGACTGGGCGACTCA
TATGATCGAACACGCGGTCTCTGCCGTCTACGATATCCCGCACGGTGGCGGACTTGCGATTCTCTTCCCGGAATGGCTCC
GCTATGTCGGGAAGACACGTCCCGAGCGCATCATTCAACTCGGTGAACGCGTCTTTGGCATTGACGTGAACGGCAAATCG
GACGAGGTGCTCGTCGAGGAGACCGTTCAGGCGTTACAAGAATTCTGGACATCGATCGGCGCACCCTCACGTCTAAGCGA
TTATGAGATTGACGCCACACACCTCGAATTGATGGCAGAACGGGCGATGGTCGCTGAACAGATTGGCCAGTACGTCCCAC
TCCGTCAACAAGACGTATCAGCAATCTTAAAAAACGCATTATAA

Upstream 100 bases:

>100_bases
CGCCTCACCCCACTATCAAACGTATCGCCAAGAAGCAGAGCCGCTTCTCGCTAGTCGCGACGTTCAATTTTTAGAAGAAA
TCAAGGAGGTTGACTAACCT

Downstream 100 bases:

>100_bases
AAAGTAGGGCCCACGTGGGTCCTACTTCATTTTGCATCCTGCAGCGCTTGGATGACTTGATTGATGACGGGGTCATGCTT
CGACTCAGTCCGGTGCGCGA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MERFQYHNPTKLLFGKGQLESLRTEIPRYGDRVLLLYGGGSIKANGLYEEVTALLADMQVTVVELSGVEPNPRLTTVQTG
IDLVHEHQIDLILAVGGGSVIDCAKGIAAGAKYDGNPWDIVTRQVPVTDALPIGTVLTLAATGSEMNGGAVITNWEAQDK
RSFGSPLTYPKFSVLDPTYTLSVPANQTVYGIVDIMSHVFEQYFHASENALLQERFGESILRTMMETAPRLVQNLNDFDA
RETMLLNGTFALNGTLSMGVKTDWATHMIEHAVSAVYDIPHGGGLAILFPEWLRYVGKTRPERIIQLGERVFGIDVNGKS
DEVLVEETVQALQEFWTSIGAPSRLSDYEIDATHLELMAERAMVAEQIGQYVPLRQQDVSAILKNAL

Sequences:

>Translated_387_residues
MERFQYHNPTKLLFGKGQLESLRTEIPRYGDRVLLLYGGGSIKANGLYEEVTALLADMQVTVVELSGVEPNPRLTTVQTG
IDLVHEHQIDLILAVGGGSVIDCAKGIAAGAKYDGNPWDIVTRQVPVTDALPIGTVLTLAATGSEMNGGAVITNWEAQDK
RSFGSPLTYPKFSVLDPTYTLSVPANQTVYGIVDIMSHVFEQYFHASENALLQERFGESILRTMMETAPRLVQNLNDFDA
RETMLLNGTFALNGTLSMGVKTDWATHMIEHAVSAVYDIPHGGGLAILFPEWLRYVGKTRPERIIQLGERVFGIDVNGKS
DEVLVEETVQALQEFWTSIGAPSRLSDYEIDATHLELMAERAMVAEQIGQYVPLRQQDVSAILKNAL
>Mature_387_residues
MERFQYHNPTKLLFGKGQLESLRTEIPRYGDRVLLLYGGGSIKANGLYEEVTALLADMQVTVVELSGVEPNPRLTTVQTG
IDLVHEHQIDLILAVGGGSVIDCAKGIAAGAKYDGNPWDIVTRQVPVTDALPIGTVLTLAATGSEMNGGAVITNWEAQDK
RSFGSPLTYPKFSVLDPTYTLSVPANQTVYGIVDIMSHVFEQYFHASENALLQERFGESILRTMMETAPRLVQNLNDFDA
RETMLLNGTFALNGTLSMGVKTDWATHMIEHAVSAVYDIPHGGGLAILFPEWLRYVGKTRPERIIQLGERVFGIDVNGKS
DEVLVEETVQALQEFWTSIGAPSRLSDYEIDATHLELMAERAMVAEQIGQYVPLRQQDVSAILKNAL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=364, Percent_Identity=39.5604395604396, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI48994951, Length=385, Percent_Identity=24.4155844155844, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789163, Length=355, Percent_Identity=26.7605633802817, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082107, Length=362, Percent_Identity=24.3093922651934, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=391, Percent_Identity=24.0409207161125, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6321181, Length=386, Percent_Identity=26.4248704663212, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42566; Mature: 42566

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFQYHNPTKLLFGKGQLESLRTEIPRYGDRVLLLYGGGSIKANGLYEEVTALLADMQV
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHCCEE
TVVELSGVEPNPRLTTVQTGIDLVHEHQIDLILAVGGGSVIDCAKGIAAGAKYDGNPWDI
EEEEEECCCCCCCEEEEHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCEE
VTRQVPVTDALPIGTVLTLAATGSEMNGGAVITNWEAQDKRSFGSPLTYPKFSVLDPTYT
EEEECCCCCCCCHHHHEEEEECCCCCCCCEEEECCCCHHHHCCCCCCCCCCEEECCCCEE
LSVPANQTVYGIVDIMSHVFEQYFHASENALLQERFGESILRTMMETAPRLVQNLNDFDA
EECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RETMLLNGTFALNGTLSMGVKTDWATHMIEHAVSAVYDIPHGGGLAILFPEWLRYVGKTR
CCEEEEECEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCC
PERIIQLGERVFGIDVNGKSDEVLVEETVQALQEFWTSIGAPSRLSDYEIDATHLELMAE
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RAMVAEQIGQYVPLRQQDVSAILKNAL
HHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MERFQYHNPTKLLFGKGQLESLRTEIPRYGDRVLLLYGGGSIKANGLYEEVTALLADMQV
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHCCEE
TVVELSGVEPNPRLTTVQTGIDLVHEHQIDLILAVGGGSVIDCAKGIAAGAKYDGNPWDI
EEEEEECCCCCCCEEEEHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCEE
VTRQVPVTDALPIGTVLTLAATGSEMNGGAVITNWEAQDKRSFGSPLTYPKFSVLDPTYT
EEEECCCCCCCCHHHHEEEEECCCCCCCCEEEECCCCHHHHCCCCCCCCCCEEECCCCEE
LSVPANQTVYGIVDIMSHVFEQYFHASENALLQERFGESILRTMMETAPRLVQNLNDFDA
EECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RETMLLNGTFALNGTLSMGVKTDWATHMIEHAVSAVYDIPHGGGLAILFPEWLRYVGKTR
CCEEEEECEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCC
PERIIQLGERVFGIDVNGKSDEVLVEETVQALQEFWTSIGAPSRLSDYEIDATHLELMAE
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RAMVAEQIGQYVPLRQQDVSAILKNAL
HHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]