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The map label for this gene is queC

Identifier: 229917716

GI number: 229917716

Start: 1948343

End: 1948987

Strand: Reverse

Name: queC

Synonym: EAT1b_1993

Alternate gene names: 229917716

Gene position: 1948987-1948343 (Counterclockwise)

Preceding gene: 229917722

Following gene: 229917715

Centisome position: 64.97

GC content: 50.54

Gene sequence:

>645_bases
ATGCAACACGAAAAAGCATTGGTCGTCTTCAGTGGTGGCCAAGATTCAACCACTTGCCTGTTTTGGGCAAAACAACAATT
CTCTCATGTGGAGGCGGTGACGTTCGCATATGGTCAACGCCATGATGCGGAAATCGAGGTCGCAAAAGAAATCGCGGCAG
AGCTCGATGTCCCACACCACATCCTCGACTTGTCCCTACTCGGACAACTCACATCGAACGCGCTCACGAGACACGATCTC
GACATCGACAATGCGGATGTTCCAAATACGTTCGTCGATGGACGCAACCATCTATTCTTATCATTTGCGGCCGTCATGGC
CAAACAACTCGGTATGCATCACATCGTGACCGGTGTATGTGAAACGGACTTTTCAGGTTACCCGGATTGCCGAGACCAAT
TCATCAAATCACTCAATGTGACACTCAATTTAGCAATGGATTATCCATTCGTCATCGACACACCGCTCATGTGGCTCGAT
AAAAAAGAGACGTGGGCACTCGCCGACGAGCTCGGTGCCTTTGACTACGTCAAAGAACGCACGCTCACTTGCTACAACGG
TGTCATCGGTTCAGGTTGTGGCGAATGTCCGGCGTGTAAGCTTCGTCAAAACGGACTCACAGCTTACGAGGAGGTGCGCG
TATGA

Upstream 100 bases:

>100_bases
CTGTCAAACGTCTTTTTATGATAAATTATATGCTTGAGGGTGACCTCCGGAGTTCGTAACCTCCTCCGACATCAAAACTA
GCGAAAAGGAAGTGTGCTTC

Downstream 100 bases:

>100_bases
AACATGCTCCATTCCTCGCTCCGACCAGTGTTGAATCAAAGCAAGAAGGCTCGCTCATCTACTGTCCGCATCGCGTTCAA
ATCGTCAAAGAAGTGACGTT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MQHEKALVVFSGGQDSTTCLFWAKQQFSHVEAVTFAYGQRHDAEIEVAKEIAAELDVPHHILDLSLLGQLTSNALTRHDL
DIDNADVPNTFVDGRNHLFLSFAAVMAKQLGMHHIVTGVCETDFSGYPDCRDQFIKSLNVTLNLAMDYPFVIDTPLMWLD
KKETWALADELGAFDYVKERTLTCYNGVIGSGCGECPACKLRQNGLTAYEEVRV

Sequences:

>Translated_214_residues
MQHEKALVVFSGGQDSTTCLFWAKQQFSHVEAVTFAYGQRHDAEIEVAKEIAAELDVPHHILDLSLLGQLTSNALTRHDL
DIDNADVPNTFVDGRNHLFLSFAAVMAKQLGMHHIVTGVCETDFSGYPDCRDQFIKSLNVTLNLAMDYPFVIDTPLMWLD
KKETWALADELGAFDYVKERTLTCYNGVIGSGCGECPACKLRQNGLTAYEEVRV
>Mature_214_residues
MQHEKALVVFSGGQDSTTCLFWAKQQFSHVEAVTFAYGQRHDAEIEVAKEIAAELDVPHHILDLSLLGQLTSNALTRHDL
DIDNADVPNTFVDGRNHLFLSFAAVMAKQLGMHHIVTGVCETDFSGYPDCRDQFIKSLNVTLNLAMDYPFVIDTPLMWLD
KKETWALADELGAFDYVKERTLTCYNGVIGSGCGECPACKLRQNGLTAYEEVRV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=212, Percent_Identity=55.188679245283, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_EXISA (C4L0V4)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886362.1
- GeneID:   7869203
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1993
- OMA:   CETDYSG
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 23859; Mature: 23859

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHEKALVVFSGGQDSTTCLFWAKQQFSHVEAVTFAYGQRHDAEIEVAKEIAAELDVPHH
CCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
ILDLSLLGQLTSNALTRHDLDIDNADVPNTFVDGRNHLFLSFAAVMAKQLGMHHIVTGVC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHH
ETDFSGYPDCRDQFIKSLNVTLNLAMDYPFVIDTPLMWLDKKETWALADELGAFDYVKER
CCCCCCCCHHHHHHHHHHCEEEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHH
TLTCYNGVIGSGCGECPACKLRQNGLTAYEEVRV
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MQHEKALVVFSGGQDSTTCLFWAKQQFSHVEAVTFAYGQRHDAEIEVAKEIAAELDVPHH
CCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
ILDLSLLGQLTSNALTRHDLDIDNADVPNTFVDGRNHLFLSFAAVMAKQLGMHHIVTGVC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHH
ETDFSGYPDCRDQFIKSLNVTLNLAMDYPFVIDTPLMWLDKKETWALADELGAFDYVKER
CCCCCCCCHHHHHHHHHHCEEEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHH
TLTCYNGVIGSGCGECPACKLRQNGLTAYEEVRV
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA