Click here to switch to the map view.

The map label for this gene is 227827143

Identifier: 227827143

GI number: 227827143

Start: 767078

End: 768247

Strand: Direct

Name: 227827143

Synonym: M1425_0817

Alternate gene names: NA

Gene position: 767078-768247 (Clockwise)

Preceding gene: 227827138

Following gene: 227827144

Centisome position: 29.4

GC content: 37.35

Gene sequence:

>1170_bases
ATGTTATTGGGTTTTTCCAGTAGATATGAAAAGGTATATCAAGGTTTGGCACTTGACCTAATAGCGGAAACTGTAAAGGA
AGCTTTAGACATGGCTAAACTAGAACCTAAGGACATAGATGGAGTTATAACCACGTGGTTACCATGGATTTTCGATGGTA
CTTTAGCAATAGGCTTTCCAGAGAATTATATTAGTGAGTACTTAGGAATAAGGCCTAAATTTACAGACTTAGTTCAATAT
GGAGGAGCTTCCGCTTTAGAAATGTTTTATAGAGCTTATAAGGCAGTAAAAAGTGGTGAGGCAGATAGAGTTTTATGTGT
AATAGGAGGTAAGGGAACTTTAATGAAAAAACAGTTAAGAGAAGGAGGATTAGAGAGGTTTTCAGAAGTTGAGCTACTAA
ATATACTAAGGAATAATCCCTTTGATGAATTCATAAGGGTATATCAAGAAATGGATCCTATATCTTTTTACGCAATGGTT
GCTGCTAGACACTCGAAATTATACGGAACTACTGATGAACAAAGAGCCTTATTAGCGGTTCAGCAGAGATATAATGCAAA
CTCTAATGAGAGGGCTTTATTTAGGGGTCCTCTAACAGTTAAGGACATTATAAATTCGCGAGTAGTATCAACTCCTCTTC
ATCTTCTTGAAATAACTTATCCTATAGATGGCGTTTTAGCCTTTATAGTAGGTAAGGGGAATTCACAGCTGAGGTCGATG
GATGTAATATCCTATGGAGATGCAATATGGCCAGAGTTTTTCGCTGAAAGGGATGTGGATATTGTTTATACTCCCACAAT
CGAGAGTGCTAAGAAGATAGACTTCAATTTAAATAAGATCGATGCTTTCGAAATATATGACGCTTTTACAATAATGGTAT
TAACTGAGCTAGAAGATTTGGGTTTAACCGAGAAAGGAAAGATAGGGAAATTCGTGGAGGAGAATGATCTGACGATAAAG
GGTAGCATACCAGTTAATACTGGAGGTGGAAGTTTAAACATGGGACAGCCTGCATATATGAGTGGGATAATCATCCTTGA
AGAAGCGTTCCTGCAATTTAATAACATGGCAAAGGGGCATCAGGTGAGTGGAGCTGATTATATATTAGTTAATGGTTTAG
GGGGTTGGAATACACACGCTACCACATTAGTAATAGGTGAGAAAAAATGA

Upstream 100 bases:

>100_bases
AATTTTATTTCAAGTTAATTTTATGAAGGTCTATCTTGGAACCATAAATATCATAAAAGTTTTTTAAGTTATTAATTATA
CACTCTAATAGTGATAGCAA

Downstream 100 bases:

>100_bases
ACTTAAATGAAATAATTCAAACCTACTACGAGTACTTTAATAAGGAGAAGTTGCCTTATATTAAGTGTACAAATTGCGGA
CACGTGTTTTATTATCCCAG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLGFSSRYEKVYQGLALDLIAETVKEALDMAKLEPKDIDGVITTWLPWIFDGTLAIGFPENYISEYLGIRPKFTDLVQY
GGASALEMFYRAYKAVKSGEADRVLCVIGGKGTLMKKQLREGGLERFSEVELLNILRNNPFDEFIRVYQEMDPISFYAMV
AARHSKLYGTTDEQRALLAVQQRYNANSNERALFRGPLTVKDIINSRVVSTPLHLLEITYPIDGVLAFIVGKGNSQLRSM
DVISYGDAIWPEFFAERDVDIVYTPTIESAKKIDFNLNKIDAFEIYDAFTIMVLTELEDLGLTEKGKIGKFVEENDLTIK
GSIPVNTGGGSLNMGQPAYMSGIIILEEAFLQFNNMAKGHQVSGADYILVNGLGGWNTHATTLVIGEKK

Sequences:

>Translated_389_residues
MLLGFSSRYEKVYQGLALDLIAETVKEALDMAKLEPKDIDGVITTWLPWIFDGTLAIGFPENYISEYLGIRPKFTDLVQY
GGASALEMFYRAYKAVKSGEADRVLCVIGGKGTLMKKQLREGGLERFSEVELLNILRNNPFDEFIRVYQEMDPISFYAMV
AARHSKLYGTTDEQRALLAVQQRYNANSNERALFRGPLTVKDIINSRVVSTPLHLLEITYPIDGVLAFIVGKGNSQLRSM
DVISYGDAIWPEFFAERDVDIVYTPTIESAKKIDFNLNKIDAFEIYDAFTIMVLTELEDLGLTEKGKIGKFVEENDLTIK
GSIPVNTGGGSLNMGQPAYMSGIIILEEAFLQFNNMAKGHQVSGADYILVNGLGGWNTHATTLVIGEKK
>Mature_389_residues
MLLGFSSRYEKVYQGLALDLIAETVKEALDMAKLEPKDIDGVITTWLPWIFDGTLAIGFPENYISEYLGIRPKFTDLVQY
GGASALEMFYRAYKAVKSGEADRVLCVIGGKGTLMKKQLREGGLERFSEVELLNILRNNPFDEFIRVYQEMDPISFYAMV
AARHSKLYGTTDEQRALLAVQQRYNANSNERALFRGPLTVKDIINSRVVSTPLHLLEITYPIDGVLAFIVGKGNSQLRSM
DVISYGDAIWPEFFAERDVDIVYTPTIESAKKIDFNLNKIDAFEIYDAFTIMVLTELEDLGLTEKGKIGKFVEENDLTIK
GSIPVNTGGGSLNMGQPAYMSGIIILEEAFLQFNNMAKGHQVSGADYILVNGLGGWNTHATTLVIGEKK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=300, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI302344760, Length=300, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI302344767, Length=300, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585051, Length=316, Percent_Identity=26.2658227848101, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19921506, Length=316, Percent_Identity=25.9493670886076, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 43381; Mature: 43381

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGFSSRYEKVYQGLALDLIAETVKEALDMAKLEPKDIDGVITTWLPWIFDGTLAIGFP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECC
ENYISEYLGIRPKFTDLVQYGGASALEMFYRAYKAVKSGEADRVLCVIGGKGTLMKKQLR
HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EGGLERFSEVELLNILRNNPFDEFIRVYQEMDPISFYAMVAARHSKLYGTTDEQRALLAV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
QQRYNANSNERALFRGPLTVKDIINSRVVSTPLHLLEITYPIDGVLAFIVGKGNSQLRSM
HHHHCCCCCCCEEEECCCHHHHHHCCHHHHCCEEEEEEECCCCEEEEEEEECCCCCCEEE
DVISYGDAIWPEFFAERDVDIVYTPTIESAKKIDFNLNKIDAFEIYDAFTIMVLTELEDL
EEHHCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHC
GLTEKGKIGKFVEENDLTIKGSIPVNTGGGSLNMGQPAYMSGIIILEEAFLQFNNMAKGH
CCCCCCCCCCEEECCCEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
QVSGADYILVNGLGGWNTHATTLVIGEKK
CCCCCCEEEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MLLGFSSRYEKVYQGLALDLIAETVKEALDMAKLEPKDIDGVITTWLPWIFDGTLAIGFP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECC
ENYISEYLGIRPKFTDLVQYGGASALEMFYRAYKAVKSGEADRVLCVIGGKGTLMKKQLR
HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EGGLERFSEVELLNILRNNPFDEFIRVYQEMDPISFYAMVAARHSKLYGTTDEQRALLAV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
QQRYNANSNERALFRGPLTVKDIINSRVVSTPLHLLEITYPIDGVLAFIVGKGNSQLRSM
HHHHCCCCCCCEEEECCCHHHHHHCCHHHHCCEEEEEEECCCCEEEEEEEECCCCCCEEE
DVISYGDAIWPEFFAERDVDIVYTPTIESAKKIDFNLNKIDAFEIYDAFTIMVLTELEDL
EEHHCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHC
GLTEKGKIGKFVEENDLTIKGSIPVNTGGGSLNMGQPAYMSGIIILEEAFLQFNNMAKGH
CCCCCCCCCCEEECCCEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
QVSGADYILVNGLGGWNTHATTLVIGEKK
CCCCCCEEEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]