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The map label for this gene is pbuX [H]

Identifier: 227815584

GI number: 227815584

Start: 2739380

End: 2740702

Strand: Reverse

Name: pbuX [H]

Synonym: BAMEG_3001

Alternate gene names: 227815584

Gene position: 2740702-2739380 (Counterclockwise)

Preceding gene: 227815585

Following gene: 227815582

Centisome position: 52.4

GC content: 38.62

Gene sequence:

>1323_bases
ATGAAGCAACATCCATTTAAAATCGCATCGCTTGGTATGCAGCATATGCTTGCTATGTATGCTGGCGCAATTATCGTTCC
GCTTATTGTGGGCGGCGGACTTGGTTTAAATCAAAAAGAGTTAACATATTTAGTCTCAATTGATTTATTAATGTGCGGCG
TTGCGACAATTTTACAAGCATTATCAAATCGCTTTTTCGGTATTGGACTCCCAGTTGTACTAGGTTGTACATTTACAGCC
GTTGGGCCGATGATTGCAATCGGAAAACAATACGGCGTGTCTTCTATTTATGGAGCAATTATTGCTGCGGGGTTATTCGT
TGTTATTTTTGCGAAATTATTTGGAAAGCTTGTAAAACTGTTTCCTCCTGTTGTAACAGGATCTGTCGTTACCGTAATTG
GAGTTACACTTGTTCCAGCAGCAATTAATGATATGGCTGGAGGAGTAGGAAGTAAGGATTTCGGTAGTCTTGAAAATTTA
GCATTAGCATTTGGTGTGTTACTATTTATTATCATTATGTATCGTTTCTTCGACGGGTTTATTCGTTCAATCTCTATTTT
ACTAGGTCTTTTATTCGGTACAATTGTTGCAGCATTTATGGGGAAAGTAAGCTTGCAAGCGGTTGGAGAAGCAGATTGGT
TCCATGGTATTCAGCCATTTTACTTCGGTACACCAACGTTTGAATTAACGCCAATTATTACGATGATTCTAGTTGCTTGC
GTAGGGATTGTAGAAGCAACAGGTGTATACTTTGCATTATCTGATATTTGCAATAAAAAGATTGGTGAAAAAGAATTAAC
AAAAGGTTATCGTGCAGAAGGGTTAGCAATGGTGTTAGGTGGTATTTTCAACGCCTTCCCATATACAACATACTCTCAAA
ACGTAGGGCTTGTTCAATTAACTGGAGTAAGAAATCGCGTGATTATTTATACTTGTGGTGGTATGTTAATCGCTCTTGGA
TTCATTCCAAAAATCGCAGCGATTACAACAATTATTCCGAAATCGGTACTTGGCGGTGCGATGTTAGCGATGTTCGGTAT
GGTAATGGCATATGGTATTAAAATGTTAAGTAGCGTTGATTTTGGAAGACAAGAAAACTTATTAATCGTTGCATGTTCTG
TTGGAATCGGGCTAGGAGTTACTGTCGTTCCTACATTATTCTCACAACTTCCAGAAAGCATTCGTATTTTAACAGATAAC
GGAATCGTACTTGGAAGTGCGTCAGCAGTACTTTTAAATATCGTATTTAATATGGTGCCGCAGCGTAAAGTGAAAGTAAA
GGATGAACCAGTTCCGATGCAAAGTGCGGTAAGAGAAGCGTAA

Upstream 100 bases:

>100_bases
TGAACAAGGAATTCGTGTTGAGTCACTAGCAGAAATTGCATCACTTGATAATAACGCAGTTACATTTGTACAGCAAGAAA
CTGCGGAGGTGAAATAAACG

Downstream 100 bases:

>100_bases
AATTGATAAAAGGTTCAAATCGTATGCGATTTGAACCTTTTATTTTTGTATTTCAAAACCGATTCGTTACTGTTATGAGA
CCTTGCTTTTCTTTTTAAGT

Product: xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLNQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGVGSKDFGSLENL
ALAFGVLLFIIIMYRFFDGFIRSISILLGLLFGTIVAAFMGKVSLQAVGEADWFHGIQPFYFGTPTFELTPIITMILVAC
VGIVEATGVYFALSDICNKKIGEKELTKGYRAEGLAMVLGGIFNAFPYTTYSQNVGLVQLTGVRNRVIIYTCGGMLIALG
FIPKIAAITTIIPKSVLGGAMLAMFGMVMAYGIKMLSSVDFGRQENLLIVACSVGIGLGVTVVPTLFSQLPESIRILTDN
GIVLGSASAVLLNIVFNMVPQRKVKVKDEPVPMQSAVREA

Sequences:

>Translated_440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLNQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGVGSKDFGSLENL
ALAFGVLLFIIIMYRFFDGFIRSISILLGLLFGTIVAAFMGKVSLQAVGEADWFHGIQPFYFGTPTFELTPIITMILVAC
VGIVEATGVYFALSDICNKKIGEKELTKGYRAEGLAMVLGGIFNAFPYTTYSQNVGLVQLTGVRNRVIIYTCGGMLIALG
FIPKIAAITTIIPKSVLGGAMLAMFGMVMAYGIKMLSSVDFGRQENLLIVACSVGIGLGVTVVPTLFSQLPESIRILTDN
GIVLGSASAVLLNIVFNMVPQRKVKVKDEPVPMQSAVREA
>Mature_440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLNQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGVGSKDFGSLENL
ALAFGVLLFIIIMYRFFDGFIRSISILLGLLFGTIVAAFMGKVSLQAVGEADWFHGIQPFYFGTPTFELTPIITMILVAC
VGIVEATGVYFALSDICNKKIGEKELTKGYRAEGLAMVLGGIFNAFPYTTYSQNVGLVQLTGVRNRVIIYTCGGMLIALG
FIPKIAAITTIIPKSVLGGAMLAMFGMVMAYGIKMLSSVDFGRQENLLIVACSVGIGLGVTVVPTLFSQLPESIRILTDN
GIVLGSASAVLLNIVFNMVPQRKVKVKDEPVPMQSAVREA

Specific function: Transport of xanthine in the cell [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=224, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI40316845, Length=224, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI44680145, Length=428, Percent_Identity=23.3644859813084, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI44680143, Length=432, Percent_Identity=23.3796296296296, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082181, Length=438, Percent_Identity=41.5525114155251, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1790087, Length=428, Percent_Identity=29.9065420560748, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082178, Length=434, Percent_Identity=32.4884792626728, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87081818, Length=456, Percent_Identity=28.0701754385965, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788843, Length=377, Percent_Identity=28.3819628647215, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17542262, Length=441, Percent_Identity=24.2630385487528, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=423, Percent_Identity=24.113475177305, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=192, Percent_Identity=28.6458333333333, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=436, Percent_Identity=22.4770642201835, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=190, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356175, Length=418, Percent_Identity=25.8373205741627, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46590; Mature: 46590

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEECCCCCCCHHHHHCCC
>Mature Secondary Structure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CCCEECCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9098051; 9384377 [H]