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The map label for this gene is xpt

Identifier: 227815585

GI number: 227815585

Start: 2740706

End: 2741299

Strand: Reverse

Name: xpt

Synonym: BAMEG_3002

Alternate gene names: 227815585

Gene position: 2741299-2740706 (Counterclockwise)

Preceding gene: 227815586

Following gene: 227815584

Centisome position: 52.41

GC content: 34.51

Gene sequence:

>594_bases
ATGAAAGTATTACAAGAAAAGATTTTGAACGAAGGAAAGGTTTTATCTGGTGATGTATTAAAGGTAGATGCATTTTTAAA
TCACCAAATTGATCCAGTACTTATGCAAGAAATCGGAAAAGAATTTGCTAAACGTTTTAAAGAAGAGAACATTACAAAAA
TCGTGACGATTGAATCTTCAGGGATTGCACCAGCAGTTATGGCTGCATTAGAGCTTGGTGTAAAAGTAATCTTTGCTAGA
AAGCGTAAATCGTTAACGTTACAAGATAATATGTATGTTGCAAACGTATATTCATTTACAAAACAAGAAACGAATGAAAT
TTCGTTATCTCGAAATCATATTGATGAAAGTGATCGCGTTTTAATTATTGATGACTTTTTAGCAAACGGTCAGGCTGCTT
TAGGTTTAATGAGCCTAGTAGAGCAAGCTGGAGCAAGTATTGCAGGAATTGGTATTGTTATTGAAAAAGCATTTCAAGAT
GGAGGAAAGAAGCTTCGTGAACAAGGAATTCGTGTTGAGTCACTAGCAGAAATTGCATCACTTGATAATAACGCAGTTAC
ATTTGTACAGCAAGAAACTGCGGAGGTGAAATAA

Upstream 100 bases:

>100_bases
TTAGCATTCTTTTTTGCGAAACTCCAAAAGCGCGTCTCTCACTTGTAACGAGTGGTGGCGGCTTTTGGAGTTTTTTTATT
GCATAAGAGGGGGAACAAAC

Downstream 100 bases:

>100_bases
ACGATGAAGCAACATCCATTTAAAATCGCATCGCTTGGTATGCAGCATATGCTTGCTATGTATGCTGGCGCAATTATCGT
TCCGCTTATTGTGGGCGGCG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK

Sequences:

>Translated_197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
>Mature_197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACAA (C3P5T8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866071.1
- ProteinModelPortal:   C3P5T8
- SMR:   C3P5T8
- EnsemblBacteria:   EBBACT00000129171
- GeneID:   7850573
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1660
- GeneTree:   EBGT00050000001498
- ProtClustDB:   PRK09219
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21632; Mature: 21632

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESS
CCHHHHHHHCCCCEECCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRV
CCHHHHHHHHHHHHHHEEECCCCCEEEECCEEEEHHHHHHHHCCCCEEHHHCCCCCCCCE
LIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIAS
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDNNAVTFVQQETAEVK
CCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESS
CCHHHHHHHCCCCEECCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRV
CCHHHHHHHHHHHHHHEEECCCCCEEEECCEEEEHHHHHHHHCCCCEEHHHCCCCCCCCE
LIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIAS
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDNNAVTFVQQETAEVK
CCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA