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The map label for this gene is phoP [H]

Identifier: 227815205

GI number: 227815205

Start: 2379072

End: 2379761

Strand: Reverse

Name: phoP [H]

Synonym: BAMEG_2616

Alternate gene names: 227815205

Gene position: 2379761-2379072 (Counterclockwise)

Preceding gene: 227815206

Following gene: 227815204

Centisome position: 45.5

GC content: 34.06

Gene sequence:

>690_bases
ATGCCAACAATTTTAGTTTTAGAAGATGAAATGCCTATTCGTAGTTTTATTGTCCTAAATTTGAAACGTGCTGGATTTTA
TGTACTAGAAGCCAGTACTGGAGAAGAAGCGTTACAAATTTTATGTGAACATACTGTAGATGTAGCTTTACTTGATGTAA
TGTTACCGGGAATGGATGGTTTTCAAGTTTGTAAAGCAATCCGGGAAGAAAATAAAAAAATAGGTATTATTATGTTAACC
GCGCGCGTACAAAATGAAGATAAAGTACAAGGGTTAGGAATTGGTGCAGATGATTATATCGCAAAGCCATTTAGTCCTGT
GGAACTAACTGCACGTATACAATCGTTACTAAGAAGAATAGAAGTACATGATGAAAAAGCGAATACTATCACATCTGGTC
CGTTTTTATTAAATATAATAGAAGAAAGATTATATAAAAGTGGACAACTAGTCGATTTAACCCCTACAGAGTATATGATA
TTACAGTATTTAATGAATCAGGCTTCAAAACCGGTTTCACGTGATGAAATTTTAAATATGATTTGGGGAACGAATTATGT
AGGAGAGACGAAAGTAGTAGATGTAAATATGAGGCGGTTACGTCAAAAGATAGAGTGTAATCCATCAGAACCTGAATTTA
TTCTTACTGTGTGGGGAAAAGGATATGTGTGGAAGGAAAGTATAAGATGA

Upstream 100 bases:

>100_bases
TCTCACGTATATGCTGTACCGAAACAACCACATTTTGAAAAAGTGAAAGCATATGTAAAGCCGCTAGCGGATTATCAACA
AGAGTAGGGAGGTGGAAATG

Downstream 100 bases:

>100_bases
AAAGAAAAGTGACTTTATATTTTATGACGGTCATTATACTTATGCTTGTATTATTTGAAGTCGTATTTTCAGTCTCCGTT
TACCGATATTATTATAATGG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGIIMLT
ARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTITSGPFLLNIIEERLYKSGQLVDLTPTEYMI
LQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Sequences:

>Translated_229_residues
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGIIMLT
ARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTITSGPFLLNIIEERLYKSGQLVDLTPTEYMI
LQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
>Mature_228_residues
PTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGIIMLTA
RVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTITSGPFLLNIIEERLYKSGQLVDLTPTEYMIL
QYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=36.283185840708, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=40.2714932126697, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=35.8407079646018, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.8828828828829, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=34.3478260869565, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=33.7899543378995, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.2342342342342, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=32.2869955156951, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=32.2727272727273, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.0316742081448, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=29.3617021276596, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.3898305084746, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=33.0434782608696, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.7709923664122, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=30.3030303030303, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=136, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26060; Mature: 25929

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDG
CCEEEEEECCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
FQVCKAIREENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRI
HHHHHHHHHCCCEEEEEEEEEEECCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHHHHH
EVHDEKANTITSGPFLLNIIEERLYKSGQLVDLTPTEYMILQYLMNQASKPVSRDEILNM
HHCCCCCCEECCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
IWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC
>Mature Secondary Structure 
PTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDG
CEEEEEECCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
FQVCKAIREENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRI
HHHHHHHHHCCCEEEEEEEEEEECCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHHHHH
EVHDEKANTITSGPFLLNIIEERLYKSGQLVDLTPTEYMILQYLMNQASKPVSRDEILNM
HHCCCCCCEECCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
IWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]