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The map label for this gene is pbpC [H]

Identifier: 227814945

GI number: 227814945

Start: 2147652

End: 2149637

Strand: Reverse

Name: pbpC [H]

Synonym: BAMEG_2356

Alternate gene names: 227814945

Gene position: 2149637-2147652 (Counterclockwise)

Preceding gene: 227814946

Following gene: 227814944

Centisome position: 41.1

GC content: 36.05

Gene sequence:

>1986_bases
TTGAGAAAAATATGGGGGATTCTTTTTCTTTGCCTAACATTCATGTTAGTCGGATGTGGTAAAGAAGAAAAACCACAAGA
AGCATTTGATACATATGCAAAAGCATGGAATAAACAAAAATTTGCAGAAATGTATGATCAATTATCAGAAAAGGCAAAAA
AAGATATTTCAAAGAAAGAATTCACTGAGAAATATGAAAAAATTTATTCTGGCATTGAAGTGAAAAACTTAAAAGTGGAA
GCAGGAGAAGTAAAGGAAGATAAAAAAGATGAAGGTCCTATTCCTTTTAAAGTAAGCATGGATACAGTGGGTGGAAAAAT
CAATTTTGGCCATGAAGCAAAAATGGTGAAAGAAAAAGATGGAGATAAAGAATCTTGGAAAGTAGATTGGACTCCTGACT
TTATCTTCCCAGGTATGACGAAAGATAGTAAAGTGCGTATGCAAACGACAGAGCCAAAACGTGGGGAAATATACGATCGT
AATGGAAAAGGTCTTGCAACGAATGGGAAAGCTTCTGAAATCGGATTGATTCCTGAAAAGTTAGGAGATACTGCTCCGCA
AACGAAAGAAACGGTAGCGAAGTTGTTAAATATGTCTGTAGAAGAAATTGATCAAAAATTAGCTGCTAAATGGGTAAAAC
CAGGGTATCTCGTACCAATTGGAATTTTACCTGAAGGGGCAACACAAAATACGTACATTGATTTACCGGGTGTTTCAACA
AAACCTGTAAATGTTCGTACATATCCATTAGGGGAAGCAGCAGCACATCTCACTGGTTATATTGGAAAAGTAAATGCTGA
AGATTTAAAAACGCTACAAAAGAAAGGCTATCAAGCGGATGATCCAGTTGGTAAAGCTGGTTTAGAGCAAGTACTGGAAG
AGAAGCTGCGCGGTAAAAAAGGCGGCCGTGTCTTTGTGGAAGATGCACAAGGAAAAGAAATTAAAAATTTAGCAAAAACA
GATGCTGTTGATGGAGAAAATGTAACTTTAACGATTGATAGTGCTGTTCAAGAAAAAACTTATAATGAAATGAAAGGCGA
AGCTGGTTCAAGCGCGGCAATTAATCCGAAAAGTGGAGAAACTCTTGCACTTGTAAGTAGCCCAGCATATGATCCTAACA
TAATTGCAAGAGGAACATCAAAAGCACAACGTGAAGCATGGAATAATGATCCAAAGAAACCGATGACGAATCGATTTACA
CAATTATCAGTTCCAGGTTCTGTGTTTAAGCCTATTACAGCAGCAATTGGTCTTGAAACGAAAACGATTGATCCAAAAGA
AGAGTTGAAAATTGAAGGGTTGAAATGGACAAAAGATTCTTCTTGGGGTAATTATTATGTAACGCGTGTAAAAGATGCAA
ATCCGATTGATTTTGATAAGGCGATGAAATACTCGGATAATATTTATTTTGCACAAGAAGCTTTGAAAATCGGAAAAGAT
AAATTTATGAGTGAAGCGAAAAAATTCGGATTCGATGAGAAGCTACCAATTGAATATGGATTCCCAGCTTCTAAAATCGC
AAATGATGGTATTAAAAATGATATTCAAATGGCAGACACAGGTTATGGACAAGGACAAGTATTAATGACACCACTCCATC
TAGCATTAACGTACGCACCAATTGTTAATGATGGAAACATACCTTCTCCATACATTATTAAAACAGATAAGCAACCAAAA
GTTTGGAAAGAGAATGTCATTTCAAAAGGCAATCAGGATATACTAAAAACTGCTATGACGAAAGTAATTAATGATCCAGA
TGGTACCGGGAAAATTGCTAAAATTGATGGTATGACGCTTGCTGGAAAAACAGGTACAGCAGAATTAAAAGTATCAAAAG
AGGCCGAAGGAAAAGAACTAGGCTGGTTCGCTGCATTTGATTTAAATTCACCAGATATGGTCATTACAATGATGATTGAA
GATGTAAAAGGTAGAGGCGGAAGTAATATCCCGGCTGAAAAAGTAAAACATGTATTTCAAAAATAA

Upstream 100 bases:

>100_bases
TTGGTTTATAGATGAGATTCGATAGTGCTATAATGAAAGGTAGCATGTGAAAATGCTAAAATTTTCAAGAGTATTAAGAT
AGTAAGAGGAGGAGAATCGA

Downstream 100 bases:

>100_bases
TATGTAATAAAAGACTAGCTCTATAATTTGTAGAGCTAGTCTTTTTATATGAAGAAATTCTTGATATTTGTATACTTAAT
TTTAAGGAAACAAAATAAAT

Product: penicillin-binding protein 3

Products: NA

Alternate protein names: PBP 3; PSPB20; Penicillin-binding protein C [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRKIWGILFLCLTFMLVGCGKEEKPQEAFDTYAKAWNKQKFAEMYDQLSEKAKKDISKKEFTEKYEKIYSGIEVKNLKVE
AGEVKEDKKDEGPIPFKVSMDTVGGKINFGHEAKMVKEKDGDKESWKVDWTPDFIFPGMTKDSKVRMQTTEPKRGEIYDR
NGKGLATNGKASEIGLIPEKLGDTAPQTKETVAKLLNMSVEEIDQKLAAKWVKPGYLVPIGILPEGATQNTYIDLPGVST
KPVNVRTYPLGEAAAHLTGYIGKVNAEDLKTLQKKGYQADDPVGKAGLEQVLEEKLRGKKGGRVFVEDAQGKEIKNLAKT
DAVDGENVTLTIDSAVQEKTYNEMKGEAGSSAAINPKSGETLALVSSPAYDPNIIARGTSKAQREAWNNDPKKPMTNRFT
QLSVPGSVFKPITAAIGLETKTIDPKEELKIEGLKWTKDSSWGNYYVTRVKDANPIDFDKAMKYSDNIYFAQEALKIGKD
KFMSEAKKFGFDEKLPIEYGFPASKIANDGIKNDIQMADTGYGQGQVLMTPLHLALTYAPIVNDGNIPSPYIIKTDKQPK
VWKENVISKGNQDILKTAMTKVINDPDGTGKIAKIDGMTLAGKTGTAELKVSKEAEGKELGWFAAFDLNSPDMVITMMIE
DVKGRGGSNIPAEKVKHVFQK

Sequences:

>Translated_661_residues
MRKIWGILFLCLTFMLVGCGKEEKPQEAFDTYAKAWNKQKFAEMYDQLSEKAKKDISKKEFTEKYEKIYSGIEVKNLKVE
AGEVKEDKKDEGPIPFKVSMDTVGGKINFGHEAKMVKEKDGDKESWKVDWTPDFIFPGMTKDSKVRMQTTEPKRGEIYDR
NGKGLATNGKASEIGLIPEKLGDTAPQTKETVAKLLNMSVEEIDQKLAAKWVKPGYLVPIGILPEGATQNTYIDLPGVST
KPVNVRTYPLGEAAAHLTGYIGKVNAEDLKTLQKKGYQADDPVGKAGLEQVLEEKLRGKKGGRVFVEDAQGKEIKNLAKT
DAVDGENVTLTIDSAVQEKTYNEMKGEAGSSAAINPKSGETLALVSSPAYDPNIIARGTSKAQREAWNNDPKKPMTNRFT
QLSVPGSVFKPITAAIGLETKTIDPKEELKIEGLKWTKDSSWGNYYVTRVKDANPIDFDKAMKYSDNIYFAQEALKIGKD
KFMSEAKKFGFDEKLPIEYGFPASKIANDGIKNDIQMADTGYGQGQVLMTPLHLALTYAPIVNDGNIPSPYIIKTDKQPK
VWKENVISKGNQDILKTAMTKVINDPDGTGKIAKIDGMTLAGKTGTAELKVSKEAEGKELGWFAAFDLNSPDMVITMMIE
DVKGRGGSNIPAEKVKHVFQK
>Mature_661_residues
MRKIWGILFLCLTFMLVGCGKEEKPQEAFDTYAKAWNKQKFAEMYDQLSEKAKKDISKKEFTEKYEKIYSGIEVKNLKVE
AGEVKEDKKDEGPIPFKVSMDTVGGKINFGHEAKMVKEKDGDKESWKVDWTPDFIFPGMTKDSKVRMQTTEPKRGEIYDR
NGKGLATNGKASEIGLIPEKLGDTAPQTKETVAKLLNMSVEEIDQKLAAKWVKPGYLVPIGILPEGATQNTYIDLPGVST
KPVNVRTYPLGEAAAHLTGYIGKVNAEDLKTLQKKGYQADDPVGKAGLEQVLEEKLRGKKGGRVFVEDAQGKEIKNLAKT
DAVDGENVTLTIDSAVQEKTYNEMKGEAGSSAAINPKSGETLALVSSPAYDPNIIARGTSKAQREAWNNDPKKPMTNRFT
QLSVPGSVFKPITAAIGLETKTIDPKEELKIEGLKWTKDSSWGNYYVTRVKDANPIDFDKAMKYSDNIYFAQEALKIGKD
KFMSEAKKFGFDEKLPIEYGFPASKIANDGIKNDIQMADTGYGQGQVLMTPLHLALTYAPIVNDGNIPSPYIIKTDKQPK
VWKENVISKGNQDILKTAMTKVINDPDGTGKIAKIDGMTLAGKTGTAELKVSKEAEGKELGWFAAFDLNSPDMVITMMIE
DVKGRGGSNIPAEKVKHVFQK

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=548, Percent_Identity=26.6423357664234, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI1786272, Length=501, Percent_Identity=25.5489021956088, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR007887
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF05223 MecA_N; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 72947; Mature: 72947

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIWGILFLCLTFMLVGCGKEEKPQEAFDTYAKAWNKQKFAEMYDQLSEKAKKDISKKE
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
FTEKYEKIYSGIEVKNLKVEAGEVKEDKKDEGPIPFKVSMDTVGGKINFGHEAKMVKEKD
HHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHCC
GDKESWKVDWTPDFIFPGMTKDSKVRMQTTEPKRGEIYDRNGKGLATNGKASEIGLIPEK
CCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCCCHHH
LGDTAPQTKETVAKLLNMSVEEIDQKLAAKWVKPGYLVPIGILPEGATQNTYIDLPGVST
HCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCC
KPVNVRTYPLGEAAAHLTGYIGKVNAEDLKTLQKKGYQADDPVGKAGLEQVLEEKLRGKK
CCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
GGRVFVEDAQGKEIKNLAKTDAVDGENVTLTIDSAVQEKTYNEMKGEAGSSAAINPKSGE
CCEEEEECCCCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCC
TLALVSSPAYDPNIIARGTSKAQREAWNNDPKKPMTNRFTQLSVPGSVFKPITAAIGLET
EEEEEECCCCCCCEEECCCCHHHHHHCCCCCCCCHHHCCEEECCCCHHHHHHHHHHCCCC
KTIDPKEELKIEGLKWTKDSSWGNYYVTRVKDANPIDFDKAMKYSDNIYFAQEALKIGKD
CCCCCHHHCEECCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEHHHHHHHHHH
KFMSEAKKFGFDEKLPIEYGFPASKIANDGIKNDIQMADTGYGQGQVLMTPLHLALTYAP
HHHHHHHHCCCCCCCCEECCCCHHHHHCCCCCCCCEECCCCCCCCCEEEEHHEEHHEEEE
IVNDGNIPSPYIIKTDKQPKVWKENVISKGNQDILKTAMTKVINDPDGTGKIAKIDGMTL
EECCCCCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEE
AGKTGTAELKVSKEAEGKELGWFAAFDLNSPDMVITMMIEDVKGRGGSNIPAEKVKHVFQ
ECCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHC
K
C
>Mature Secondary Structure
MRKIWGILFLCLTFMLVGCGKEEKPQEAFDTYAKAWNKQKFAEMYDQLSEKAKKDISKKE
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
FTEKYEKIYSGIEVKNLKVEAGEVKEDKKDEGPIPFKVSMDTVGGKINFGHEAKMVKEKD
HHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHCC
GDKESWKVDWTPDFIFPGMTKDSKVRMQTTEPKRGEIYDRNGKGLATNGKASEIGLIPEK
CCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCCCHHH
LGDTAPQTKETVAKLLNMSVEEIDQKLAAKWVKPGYLVPIGILPEGATQNTYIDLPGVST
HCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCC
KPVNVRTYPLGEAAAHLTGYIGKVNAEDLKTLQKKGYQADDPVGKAGLEQVLEEKLRGKK
CCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
GGRVFVEDAQGKEIKNLAKTDAVDGENVTLTIDSAVQEKTYNEMKGEAGSSAAINPKSGE
CCEEEEECCCCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCC
TLALVSSPAYDPNIIARGTSKAQREAWNNDPKKPMTNRFTQLSVPGSVFKPITAAIGLET
EEEEEECCCCCCCEEECCCCHHHHHHCCCCCCCCHHHCCEEECCCCHHHHHHHHHHCCCC
KTIDPKEELKIEGLKWTKDSSWGNYYVTRVKDANPIDFDKAMKYSDNIYFAQEALKIGKD
CCCCCHHHCEECCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEHHHHHHHHHH
KFMSEAKKFGFDEKLPIEYGFPASKIANDGIKNDIQMADTGYGQGQVLMTPLHLALTYAP
HHHHHHHHCCCCCCCCEECCCCHHHHHCCCCCCCCEECCCCCCCCCEEEEHHEEHHEEEE
IVNDGNIPSPYIIKTDKQPKVWKENVISKGNQDILKTAMTKVINDPDGTGKIAKIDGMTL
EECCCCCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEE
AGKTGTAELKVSKEAEGKELGWFAAFDLNSPDMVITMMIEDVKGRGGSNIPAEKVKHVFQ
ECCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 3145906 [H]