The gene/protein map for NC_012581 is currently unavailable.
Definition Bacillus anthracis str. CDC 684, complete genome.
Accession NC_012581
Length 5,230,115

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The map label for this gene is plsC [H]

Identifier: 227814943

GI number: 227814943

Start: 2145943

End: 2146662

Strand: Reverse

Name: plsC [H]

Synonym: BAMEG_2354

Alternate gene names: 227814943

Gene position: 2146662-2145943 (Counterclockwise)

Preceding gene: 227814944

Following gene: 227814941

Centisome position: 41.04

GC content: 36.81

Gene sequence:

>720_bases
ATGATTCAAACGTTTTTTAAAATCTTTTATTTAATTTTAATCGTAATTGCGATTACACCGAGAATGTGGCGGCTTAAAAG
ACAAGTAAATACGATGTCGCCACAAGAAAAAGATAATGCTGTGTACAAAACGACAAATTGGTTTGGTAAGAAAATGGTAC
GTGTAGCAGGGGGAACAGTAGAAGTGAAAGGACTTGAAAATGTTCCGAAAGACAAGCCGGTACTAGTTGTAAGTAATCAC
CAGAGTAATATGGATATCCCTGTTTTACTAGGTTATTTAAATAAACCAATTGGCTTCGTTTCAAAGGCAGAAATTAAAAA
GTTCCCAGTTGTACCAACTTGGATGGAACTTATGAATTGTGTATTTATGGATCGTAGCGATCGCCGTCAATCACTTCAAG
CGATTAAAGATGGAATTGAGCTATTGAAGAATGGGCATTCTATCGTAATTTTCCCTGAAGGAACGAGAAGTAAGGGTGGC
GAAATTGGAGAGTTTAAGGCTGGGAGTTTTCACCTTGCTGTAAAATCTGGTGTAGCAATCTTACCTGTAACATTAGATGG
GACATATAAAATGTTTGAAGCGAATGGAAACCGTATGAAGTCAGCTCGTGCAACAGTAACAATTTCTAAGCCGATTACAC
CTGAAGAGTATGCGAATATGGATATTAAAGAGTTAACGAAGCATACACAAGATGTTATCGCATCAAAATTACATAAGTAA

Upstream 100 bases:

>100_bases
TAAAAATGTCCAAACACTTGCTGTTTGGACATTTTTTCTTCTTTTTCCTTCGTTTGTCTAGTATAATGAAGGTCGGAATG
ATAATAGGTGGGGGTTCTGT

Downstream 100 bases:

>100_bases
TAAAAAAGGTTTCAGCTTATATAAGCTGAAACCTTTTTTATTATGCTGTAGGTAAGACGTAAAAGAGTACGCAGAAGAAC
ATCATTGCACTACCACCTAA

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIQTFFKIFYLILIVIAITPRMWRLKRQVNTMSPQEKDNAVYKTTNWFGKKMVRVAGGTVEVKGLENVPKDKPVLVVSNH
QSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMDRSDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGG
EIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGNRMKSARATVTISKPITPEEYANMDIKELTKHTQDVIASKLHK

Sequences:

>Translated_239_residues
MIQTFFKIFYLILIVIAITPRMWRLKRQVNTMSPQEKDNAVYKTTNWFGKKMVRVAGGTVEVKGLENVPKDKPVLVVSNH
QSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMDRSDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGG
EIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGNRMKSARATVTISKPITPEEYANMDIKELTKHTQDVIASKLHK
>Mature_239_residues
MIQTFFKIFYLILIVIAITPRMWRLKRQVNTMSPQEKDNAVYKTTNWFGKKMVRVAGGTVEVKGLENVPKDKPVLVVSNH
QSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMDRSDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGG
EIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGNRMKSARATVTISKPITPEEYANMDIKELTKHTQDVIASKLHK

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=175, Percent_Identity=28, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI15100175, Length=175, Percent_Identity=28, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI6041665, Length=181, Percent_Identity=26.5193370165746, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1789395, Length=194, Percent_Identity=28.3505154639175, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564032, Length=181, Percent_Identity=25.414364640884, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=202, Percent_Identity=32.1782178217822, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281364648, Length=242, Percent_Identity=29.3388429752066, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24582856, Length=242, Percent_Identity=29.3388429752066, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24582854, Length=242, Percent_Identity=29.3388429752066, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24641614, Length=206, Percent_Identity=26.2135922330097, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641612, Length=206, Percent_Identity=26.2135922330097, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26896; Mature: 26896

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTFFKIFYLILIVIAITPRMWRLKRQVNTMSPQEKDNAVYKTTNWFGKKMVRVAGGTV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCCEE
EVKGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNC
EECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHH
VFMDRSDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAI
HHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEE
LPVTLDGTYKMFEANGNRMKSARATVTISKPITPEEYANMDIKELTKHTQDVIASKLHK
EEEEECCCEEEEECCCCEEECCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQTFFKIFYLILIVIAITPRMWRLKRQVNTMSPQEKDNAVYKTTNWFGKKMVRVAGGTV
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCCEE
EVKGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNC
EECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHH
VFMDRSDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAI
HHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEE
LPVTLDGTYKMFEANGNRMKSARATVTISKPITPEEYANMDIKELTKHTQDVIASKLHK
EEEEECCCEEEEECCCCEEECCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]