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The map label for this gene is pssA [H]

Identifier: 227080527

GI number: 227080527

Start: 314437

End: 315777

Strand: Reverse

Name: pssA [H]

Synonym: VCM66_0299

Alternate gene names: 227080527

Gene position: 315777-314437 (Counterclockwise)

Preceding gene: 227080529

Following gene: 227080519

Centisome position: 10.92

GC content: 44.74

Gene sequence:

>1341_bases
ATGATTGCTCGAAGAAACCCAATCGAACAACTACCAGCGATTGCGCAAGATCCTGACAAATTTGGCGTACTGCTCTCGGC
TGCAGAATTTCGAACTCATTTGGTTGAATCGATTCGTCAGGCACGCAAACGTATCTACCTCGTTGCACTTTATTTAGAAA
ATGACGATGCTGGCCGTGAAATTCTTACTGAACTCTATGCCGCCAAGCAGCGTAACCCAGGACTCGAAATACATATTTGT
GTTGACTGGCACCGTGCTCAGCGTGGCTTGATCGGTGCAGCAGAATCCGAAGGCAATGCAGCCATGTATCGTGACTTTGC
TCAGCAACATGAGCACTGTATTCCTGTTTATGGCATACCGGTTAGAGGGCGGGAAGTCTTTGGCGTTCTGCATCTAAAAG
GCTTCATTATTGATGATCAAGTCATCTACAGCGGTGCGAGCCTCAATAATGTCTATCTCCAGTTTCATGGCCGCTATCGT
TTTGATCGCTACCATACCTTAGAAAATGCTGAACTTGCCGACAGCATGGTGCATTTTATCCAACAAGAAATGCTGGCTCA
CCCGGCTGTCAATAACCTCGCTTGTGGTAGCAAACCCACCACAAAAGAGATTAAGTCTGATATCCGCCAATTCCGAGCTT
CACTTGCTCAAGCCAATTACCAATTTGCTAAACAGAAAGTGAATGAAGGTCAAGTCGCTGTCACACCCTTGGTTGGACTC
GGTCGACGCAGAAATCGGTTGAACCAAAGCATTATCCAATTGTTAGCCTCTGCTAAAGATGAAGTGTTTATCTGCACGCC
ATACTTTAATTTCCCGCCGAGTATCGCTAAAGAGGTGAAAAAAGCACTGCGACGTGGCGTGAAAGTCCATATTGTGATTG
GCGATAAAACCGCGAATGACTTCTACATTGCACCAGAAGAGCCATTCAAGACTATCGGTGGCTTACCTTACTTGTATGAA
CTTAATCTGCGCCGCTTTGCGAAAGCCAATGAAGCTCATATTGCAAGCCGCAAGCTCTCAATCCACCTCTGGAAGCATGA
AAATCACAGCTTTCATCTCAAGGGAATTTGGGTGGATAAACGTTATATGCTCATCACAGGTAATAACCTCAATCCACGCG
CTTGGAAGCTCGACCTCGAAAATGCAATTTTAATTCGTGATGATTACCATCACCTTACTACCAAATTTGAAGCTGAAATT
GACAATATTCTGCAGCATACTCAGTTAATCTGTACTTATAAGCAAATTGAAAAACCCGAGCACTACCCAGAAAAGGTACA
ACGCTTAGTACGCCGAATCATGCGTCTAAAAGCCGATCGTGTCCTCAAACAAATCTTATAA

Upstream 100 bases:

>100_bases
AAGTAATGTCAAGAATGGTCGCCATTTCTAGCCTTTTCTTAACCAGTTTTGGTAATATCCACTGCTCGCAATTTTGCACA
CAACAAGGTAATGCATCCCA

Downstream 100 bases:

>100_bases
TCAACGCTTACACTACCAGCCGATGCATTCGCATCGGCTTTTTTATTGCTCAATATAGCCATCCGAAACGACTATGCACT
GACAGAAGCTTTATTGAAAA

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIARRNPIEQLPAIAQDPDKFGVLLSAAEFRTHLVESIRQARKRIYLVALYLENDDAGREILTELYAAKQRNPGLEIHIC
VDWHRAQRGLIGAAESEGNAAMYRDFAQQHEHCIPVYGIPVRGREVFGVLHLKGFIIDDQVIYSGASLNNVYLQFHGRYR
FDRYHTLENAELADSMVHFIQQEMLAHPAVNNLACGSKPTTKEIKSDIRQFRASLAQANYQFAKQKVNEGQVAVTPLVGL
GRRRNRLNQSIIQLLASAKDEVFICTPYFNFPPSIAKEVKKALRRGVKVHIVIGDKTANDFYIAPEEPFKTIGGLPYLYE
LNLRRFAKANEAHIASRKLSIHLWKHENHSFHLKGIWVDKRYMLITGNNLNPRAWKLDLENAILIRDDYHHLTTKFEAEI
DNILQHTQLICTYKQIEKPEHYPEKVQRLVRRIMRLKADRVLKQIL

Sequences:

>Translated_446_residues
MIARRNPIEQLPAIAQDPDKFGVLLSAAEFRTHLVESIRQARKRIYLVALYLENDDAGREILTELYAAKQRNPGLEIHIC
VDWHRAQRGLIGAAESEGNAAMYRDFAQQHEHCIPVYGIPVRGREVFGVLHLKGFIIDDQVIYSGASLNNVYLQFHGRYR
FDRYHTLENAELADSMVHFIQQEMLAHPAVNNLACGSKPTTKEIKSDIRQFRASLAQANYQFAKQKVNEGQVAVTPLVGL
GRRRNRLNQSIIQLLASAKDEVFICTPYFNFPPSIAKEVKKALRRGVKVHIVIGDKTANDFYIAPEEPFKTIGGLPYLYE
LNLRRFAKANEAHIASRKLSIHLWKHENHSFHLKGIWVDKRYMLITGNNLNPRAWKLDLENAILIRDDYHHLTTKFEAEI
DNILQHTQLICTYKQIEKPEHYPEKVQRLVRRIMRLKADRVLKQIL
>Mature_446_residues
MIARRNPIEQLPAIAQDPDKFGVLLSAAEFRTHLVESIRQARKRIYLVALYLENDDAGREILTELYAAKQRNPGLEIHIC
VDWHRAQRGLIGAAESEGNAAMYRDFAQQHEHCIPVYGIPVRGREVFGVLHLKGFIIDDQVIYSGASLNNVYLQFHGRYR
FDRYHTLENAELADSMVHFIQQEMLAHPAVNNLACGSKPTTKEIKSDIRQFRASLAQANYQFAKQKVNEGQVAVTPLVGL
GRRRNRLNQSIIQLLASAKDEVFICTPYFNFPPSIAKEVKKALRRGVKVHIVIGDKTANDFYIAPEEPFKTIGGLPYLYE
LNLRRFAKANEAHIASRKLSIHLWKHENHSFHLKGIWVDKRYMLITGNNLNPRAWKLDLENAILIRDDYHHLTTKFEAEI
DNILQHTQLICTYKQIEKPEHYPEKVQRLVRRIMRLKADRVLKQIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=420, Percent_Identity=49.5238095238095, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25143331, Length=462, Percent_Identity=21.8614718614719, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28572961, Length=453, Percent_Identity=23.6203090507726, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 51465; Mature: 51465

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARRNPIEQLPAIAQDPDKFGVLLSAAEFRTHLVESIRQARKRIYLVALYLENDDAGRE
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHH
ILTELYAAKQRNPGLEIHICVDWHRAQRGLIGAAESEGNAAMYRDFAQQHEHCIPVYGIP
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECC
VRGREVFGVLHLKGFIIDDQVIYSGASLNNVYLQFHGRYRFDRYHTLENAELADSMVHFI
CCCHHHEEEEEEEEEEEECHHEECCCCCCEEEEEEECCEECCHHHCCCCHHHHHHHHHHH
QQEMLAHPAVNNLACGSKPTTKEIKSDIRQFRASLAQANYQFAKQKVNEGQVAVTPLVGL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHC
GRRRNRLNQSIIQLLASAKDEVFICTPYFNFPPSIAKEVKKALRRGVKVHIVIGDKTAND
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
FYIAPEEPFKTIGGLPYLYELNLRRFAKANEAHIASRKLSIHLWKHENHSFHLKGIWVDK
EEECCCCHHHHHCCCCEEEEECHHHHHCCCHHHHEEEEEEEEEEECCCCEEEEEEEEEEC
RYMLITGNNLNPRAWKLDLENAILIRDDYHHLTTKFEAEIDNILQHTQLICTYKQIEKPE
EEEEEECCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYPEKVQRLVRRIMRLKADRVLKQIL
CCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIARRNPIEQLPAIAQDPDKFGVLLSAAEFRTHLVESIRQARKRIYLVALYLENDDAGRE
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHH
ILTELYAAKQRNPGLEIHICVDWHRAQRGLIGAAESEGNAAMYRDFAQQHEHCIPVYGIP
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECC
VRGREVFGVLHLKGFIIDDQVIYSGASLNNVYLQFHGRYRFDRYHTLENAELADSMVHFI
CCCHHHEEEEEEEEEEEECHHEECCCCCCEEEEEEECCEECCHHHCCCCHHHHHHHHHHH
QQEMLAHPAVNNLACGSKPTTKEIKSDIRQFRASLAQANYQFAKQKVNEGQVAVTPLVGL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHC
GRRRNRLNQSIIQLLASAKDEVFICTPYFNFPPSIAKEVKKALRRGVKVHIVIGDKTAND
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
FYIAPEEPFKTIGGLPYLYELNLRRFAKANEAHIASRKLSIHLWKHENHSFHLKGIWVDK
EEECCCCHHHHHCCCCEEEEECHHHHHCCCHHHHEEEEEEEEEEECCCCEEEEEEEEEEC
RYMLITGNNLNPRAWKLDLENAILIRDDYHHLTTKFEAEIDNILQHTQLICTYKQIEKPE
EEEEEECCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYPEKVQRLVRRIMRLKADRVLKQIL
CCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]