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The map label for this gene is 227080513

Identifier: 227080513

GI number: 227080513

Start: 291999

End: 292670

Strand: Reverse

Name: 227080513

Synonym: VCM66_0284

Alternate gene names: NA

Gene position: 292670-291999 (Counterclockwise)

Preceding gene: 227080514

Following gene: 227080512

Centisome position: 10.12

GC content: 50.89

Gene sequence:

>672_bases
GTGGCTCGGTTATCACTATCAAATTCGCGATTGAGGTGGCTGATGAACTGGTTATTACGCCGTTATTGGCACGCGAAACT
CAAAGGTTCTCCCTATCAACGGCTGTTTGAAACCGCGCGCCATCACGAGTACGTCTCGCTCGACTGTGAAACCACCAGCT
TAGATCCTAAACGCGCTGAGTTAGTGACCATCGCCGCAACCAAGATCGTTGATAACCGCATTATCACCAGTCAACCCTTT
GAGGTGCGCCTGTGCGCGCCACAATCGCTCGACTCGGGTTCAGTGCGGATTCACCGTATCCGCCACCAAGATCTGCACGA
TGGTCTGAGCGAAAAAGAGGCGCTTCTCCAACTGATTGAGTTTATTGGCAATCGTCCCTTGGTCGGCTACCACATTCGTT
ACGATAAGACGATTTTGGATATCGCCTGTCGTAAACATCTCGGGTTTCCACTCCCCAACCGACTGATTGAGGTGAGCCAG
ATCTATCACGATAAACTGGAAAAACACCTGCCCAATGCCTATTTCGATCTCAGTTTAGAGGCGATCTGCCGCCATCTGGA
TCTGCCACTGCAAGACAAACATGATGCGCTGCAAGATGCGATTGCCGCCGCTTTGGTGTTTGTGCGTTTAACCAAAGGCG
ATCTGCCACAATTTATTGCACCGGGTGTGTAA

Upstream 100 bases:

>100_bases
GCAATCAGCACAGCACCAACCAACTCGACTTCAAACAACTCGACCGCACTGAACGCGATTTATTGCGCCATAGCCTGCAT
GTGGTGAAAAAATTTAAGCA

Downstream 100 bases:

>100_bases
CGCCGAAAGTCGGCGGCGAGATCTCTCCCGCTTGTTTGCCGCTTATTCGCCTTGCACACATATCCCATCAGGCTTTCATC
CTAAAGTCTAATTGTAGAAA

Product: DNA polymerase III subunit epsilon

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Epsilon Subunit; Exonuclease RNAse T And DNA Polymerase III; Exonuclease; Exonuclease Family Protein; Exonuclease RNAase T And DNA Polymerase III; DNA Polymerase IIIsubunit Epsilon; Exonuclease Superfamily; DNA Poymerase; PAS/PAC Sensor Protein

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MARLSLSNSRLRWLMNWLLRRYWHAKLKGSPYQRLFETARHHEYVSLDCETTSLDPKRAELVTIAATKIVDNRIITSQPF
EVRLCAPQSLDSGSVRIHRIRHQDLHDGLSEKEALLQLIEFIGNRPLVGYHIRYDKTILDIACRKHLGFPLPNRLIEVSQ
IYHDKLEKHLPNAYFDLSLEAICRHLDLPLQDKHDALQDAIAAALVFVRLTKGDLPQFIAPGV

Sequences:

>Translated_223_residues
MARLSLSNSRLRWLMNWLLRRYWHAKLKGSPYQRLFETARHHEYVSLDCETTSLDPKRAELVTIAATKIVDNRIITSQPF
EVRLCAPQSLDSGSVRIHRIRHQDLHDGLSEKEALLQLIEFIGNRPLVGYHIRYDKTILDIACRKHLGFPLPNRLIEVSQ
IYHDKLEKHLPNAYFDLSLEAICRHLDLPLQDKHDALQDAIAAALVFVRLTKGDLPQFIAPGV
>Mature_222_residues
ARLSLSNSRLRWLMNWLLRRYWHAKLKGSPYQRLFETARHHEYVSLDCETTSLDPKRAELVTIAATKIVDNRIITSQPFE
VRLCAPQSLDSGSVRIHRIRHQDLHDGLSEKEALLQLIEFIGNRPLVGYHIRYDKTILDIACRKHLGFPLPNRLIEVSQI
YHDKLEKHLPNAYFDLSLEAICRHLDLPLQDKHDALQDAIAAALVFVRLTKGDLPQFIAPGV

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 25755; Mature: 25624

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLSLSNSRLRWLMNWLLRRYWHAKLKGSPYQRLFETARHHEYVSLDCETTSLDPKRAE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHH
LVTIAATKIVDNRIITSQPFEVRLCAPQSLDSGSVRIHRIRHQDLHDGLSEKEALLQLIE
EEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHH
FIGNRPLVGYHIRYDKTILDIACRKHLGFPLPNRLIEVSQIYHDKLEKHLPNAYFDLSLE
HHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCHH
AICRHLDLPLQDKHDALQDAIAAALVFVRLTKGDLPQFIAPGV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARLSLSNSRLRWLMNWLLRRYWHAKLKGSPYQRLFETARHHEYVSLDCETTSLDPKRAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHH
LVTIAATKIVDNRIITSQPFEVRLCAPQSLDSGSVRIHRIRHQDLHDGLSEKEALLQLIE
EEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHH
FIGNRPLVGYHIRYDKTILDIACRKHLGFPLPNRLIEVSQIYHDKLEKHLPNAYFDLSLE
HHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCHH
AICRHLDLPLQDKHDALQDAIAAALVFVRLTKGDLPQFIAPGV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA