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The map label for this gene is galE-1 [H]

Identifier: 227080477

GI number: 227080477

Start: 252119

End: 253090

Strand: Direct

Name: galE-1 [H]

Synonym: VCM66_0247

Alternate gene names: 227080477

Gene position: 252119-253090 (Clockwise)

Preceding gene: 227080473

Following gene: 227080478

Centisome position: 8.72

GC content: 45.06

Gene sequence:

>972_bases
ATGGAACCAGATAATCAAACACCATTAAAAATACTTGTGACTGGAGCATCTGGCTTTGTCGGTTTGCGAGTACTCACCCA
AGCGCAAAATATAGGGTATGCACTGGTTGCGCAATCGCGCAGCCAACAACCCTATTCATTTGAGCAGGTATTGCTTGATA
TCACACCAAATACAGATTGGGAGAGAGCTTTAGTCGGTGTCGATTGTGTAGTTCATTGCGCCGCTAGAGTTCACCAAATG
CAAGAAACAGAAGCGGATGCCCTTAAAGCGTATCGTGATGTGAATACACAAGGCACTCTGAATTTGGCGAAGCAAGCAGT
ATCTGCTGGAGTCAAAAGATTTATCTTTTTAAGCTCAATTAAAGTCAACGGTGAGCAAACCAAAGCTGGGTCTGCTTTTC
AGCATGATGATCAACACATTCCCTCTGACCCTTACGGCTTAAGTAAATATGAGGCGGAACAACAGTTATTAGAGCTCGCA
GCAGAAACTGGACTTGAAGTTGTGATCATTCGTCCACCGTTAGTGTATGGCGAAGGGGTTAAGGCTAACTTCCTTTCTAT
GATGAATTGGGTCAAAAAGCAAATTCCCTTACCTCTTGGTGCGGTGGGGAATATGCGTAGTCTGGTGTATTTGGACAATT
TAGTCGATCTAATCTTAGTTTGTTGCCAGCACCCCAAAGCTGCAGGGGAGATTTTTTTAGTTTCAGATAACCACGACGTT
TCTTTGACCACGCTTCTTAGAACTATCGCCCAAGCAATGCAGATTCGCCCCCGATTATTACCCATTCCACAAACCGGACT
GCAGTGGTTACTGAGGCTATTGGGTAAGCCAGAGCTGGGGCAGCGCTTATGCGGTAACTTACAACTGGATATCGCTCATA
CCCAAAAAACACTACACTGGTCGCCACCTGTGAGTTTCGAACAGGGCATAGCGCGCACGGTAAATTTCTACTTATCTCAA
TCATCTAAGTGA

Upstream 100 bases:

>100_bases
GCGTTATATTAGTATCGCCCGAATTGTAGTTTGCTTGAGTAGCGTTTGCCAGACTCATGATGCTGATCGTTGGCATAGTT
TTGTAAAAAGATAGGGTAAG

Downstream 100 bases:

>100_bases
TAAAGACATGGTTATTCGATTTCTTGATTTTATTTTTGCTCTAGCTGGGCTGTTGTTACTCTGGCCTGTGTTATTGATTG
TGTGCATTTTGGGCTATTTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MEPDNQTPLKILVTGASGFVGLRVLTQAQNIGYALVAQSRSQQPYSFEQVLLDITPNTDWERALVGVDCVVHCAARVHQM
QETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSIKVNGEQTKAGSAFQHDDQHIPSDPYGLSKYEAEQQLLELA
AETGLEVVIIRPPLVYGEGVKANFLSMMNWVKKQIPLPLGAVGNMRSLVYLDNLVDLILVCCQHPKAAGEIFLVSDNHDV
SLTTLLRTIAQAMQIRPRLLPIPQTGLQWLLRLLGKPELGQRLCGNLQLDIAHTQKTLHWSPPVSFEQGIARTVNFYLSQ
SSK

Sequences:

>Translated_323_residues
MEPDNQTPLKILVTGASGFVGLRVLTQAQNIGYALVAQSRSQQPYSFEQVLLDITPNTDWERALVGVDCVVHCAARVHQM
QETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSIKVNGEQTKAGSAFQHDDQHIPSDPYGLSKYEAEQQLLELA
AETGLEVVIIRPPLVYGEGVKANFLSMMNWVKKQIPLPLGAVGNMRSLVYLDNLVDLILVCCQHPKAAGEIFLVSDNHDV
SLTTLLRTIAQAMQIRPRLLPIPQTGLQWLLRLLGKPELGQRLCGNLQLDIAHTQKTLHWSPPVSFEQGIARTVNFYLSQ
SSK
>Mature_323_residues
MEPDNQTPLKILVTGASGFVGLRVLTQAQNIGYALVAQSRSQQPYSFEQVLLDITPNTDWERALVGVDCVVHCAARVHQM
QETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSIKVNGEQTKAGSAFQHDDQHIPSDPYGLSKYEAEQQLLELA
AETGLEVVIIRPPLVYGEGVKANFLSMMNWVKKQIPLPLGAVGNMRSLVYLDNLVDLILVCCQHPKAAGEIFLVSDNHDV
SLTTLLRTIAQAMQIRPRLLPIPQTGLQWLLRLLGKPELGQRLCGNLQLDIAHTQKTLHWSPPVSFEQGIARTVNFYLSQ
SSK

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116268111, Length=275, Percent_Identity=23.2727272727273, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPDNQTPLKILVTGASGFVGLRVLTQAQNIGYALVAQSRSQQPYSFEQVLLDITPNTDW
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHEEEECCCCCCH
ERALVGVDCVVHCAARVHQMQETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEE
KVNGEQTKAGSAFQHDDQHIPSDPYGLSKYEAEQQLLELAAETGLEVVIIRPPLVYGEGV
EECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEECCCC
KANFLSMMNWVKKQIPLPLGAVGNMRSLVYLDNLVDLILVCCQHPKAAGEIFLVSDNHDV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
SLTTLLRTIAQAMQIRPRLLPIPQTGLQWLLRLLGKPELGQRLCGNLQLDIAHTQKTLHW
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCEEEEEEECCCEEEC
SPPVSFEQGIARTVNFYLSQSSK
CCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEPDNQTPLKILVTGASGFVGLRVLTQAQNIGYALVAQSRSQQPYSFEQVLLDITPNTDW
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHEEEECCCCCCH
ERALVGVDCVVHCAARVHQMQETEADALKAYRDVNTQGTLNLAKQAVSAGVKRFIFLSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEE
KVNGEQTKAGSAFQHDDQHIPSDPYGLSKYEAEQQLLELAAETGLEVVIIRPPLVYGEGV
EECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEECCCC
KANFLSMMNWVKKQIPLPLGAVGNMRSLVYLDNLVDLILVCCQHPKAAGEIFLVSDNHDV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
SLTTLLRTIAQAMQIRPRLLPIPQTGLQWLLRLLGKPELGQRLCGNLQLDIAHTQKTLHW
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCEEEEEEECCCEEEC
SPPVSFEQGIARTVNFYLSQSSK
CCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]