| Definition | Vibrio cholerae M66-2 chromosome I, complete genome. |
|---|---|
| Accession | NC_012578 |
| Length | 2,892,523 |
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The map label for this gene is cyaA [H]
Identifier: 227080358
GI number: 227080358
Start: 116018
End: 118549
Strand: Direct
Name: cyaA [H]
Synonym: VCM66_0122
Alternate gene names: 227080358
Gene position: 116018-118549 (Clockwise)
Preceding gene: 227080352
Following gene: 227080360
Centisome position: 4.01
GC content: 48.82
Gene sequence:
>2532_bases TTGCAGGCTTATACTCAGACCTTAATCCATAGACTTGATAAGCTAAACCGGCAACGTATTGAGCGTGCGCTGGCTCTTAT GGATTTGCAAAGTCAACGTGTTTTCCACCTCATTCCCGCACTATTTCAATTTAATCATCCTCTGATCCCCGGTTATTTTT CTGCTGATACGCCTTTCGGTATCCATCTGTTTGAAGCCAATCCTATCCAGCAGCAATTCATCGATGATGCTCAGTTGACG CTCGGCGAGCCGTTAACGCCAGCTGACAATCCGGCGATTTTAGGCTTGTATACGATGGGCAGTACCTCATCGATCGGTCA AAGCACATCGAGCGATCTGGATATTTGGGTCTGTGTCTCTGCTCAAATGAGTTGTGAGGCGCGCGACAACCTCTCCAGTA AATGTCTGCTCATTACCGATTGGGCGAAAAGTCAGGGTGTTGAAGCCAATTTCTTCATCATGAATGAAGAGCGTTTTCGC CATAACCATTCCGAAGCGTTAAGCGGTGAAAACTGTGGTTCATCACAGCACTTATTATTATTGGATGAGTTTTATCGCTC TGCGGTGCGCTTAGCGGGCAAGCGACTGCTGTGGCAAATCGTGCCACCAGAAATGGAAGAGTGCTACGACGAATATGTTC ACGAGCTCTGTTCAAATGGGTATTTGAACTGCAATGAATGGATCGATTTTGGCAAGTTAAACCGCATTCCGGCTGAAGAG TACTTTGGCGCGAACTTGTGGCAACTGTATAAGAGCATTGACTCGCCTTATAAATCGGTACTGAAAGCCATTTTGCTTGA AGCCTATTCGTGGGAGTACCCGCACACTCAACTGTTGAGTATCGACAGCAAACGCCGTTTCTTTGCCGATGAACCGGATC TGTACGGCATGGACTCTTACTATCAGATGTTAGAGAAAGTGACGCGCTATTTGGTGCGAATTGGTGATAGCACGCGCCTT GATTTAGTGCGCCGCTGTTTCTATCTCAAAACCCATGAGAAGTTGTCGCGTGAGCCGGGCGTCGGCTCGATGCCTTGGCG TCGTGAAGCGTTACGGGAACTGACCAGCGAATGGCAATGGAGCGCAGATTTGATTGCCGAGCTCGATAACCGTCGTCACT GGAAAGTCGAGCAAGTGAAGGTCGTGCACCACGCACTGCTTGATGCCTTGATGCTCAGCTATCGTAACCTGATCCAGTTT GCGCGTCGTAATGACATCACCTCGGCCATTAGCCCACAAGATATCTCGATTTTGGCGCGTAAACTGTACGCGGCGTTTGA AGTGCTGCCGGGGAAAGTCACACTGCTCAACCCACAAATTTCCCCAGACCTGCATGAGCCCGATTTAAGTTTTATTGAGG TTTGTGCTGGACGCACCAATAAGCCCGGTTGGTATCTCTACAAGCAGCCGCTGCAGGCGCAGCGCTTGATTGGTCAGCCG TATCTTGAGCACAACGAATACTTGAGTAAATTGGTGGCTTGGGCCTTTTTTAATGGCCTGATCACTGAGTCGACTCGTTT GCATGCGGTGGTGCGTGAAGCGCAGCTGGACATCGACAAGTTCTACCAAATGGTCAGCGATCTGCGTAATACCTTTTCGC TGCGTAAGCGTCGCCCTACTATGCAAGCGCTGGCCAATCCTTGTGAGATTAGCCAGCTTGCCATGTTCATCAATTTTGAA CACGACCCAACCAGTGAATTGAGTGGGAAAGCGCTGAAAGTCGACCTGAAAAATATCGATATTTTTAGTTTTGGTGCTGA GCAGAAATGCTTAGTCGGCAGTGTCGATTTGGTGTATCGCAACTCGTGGCAAGAAGTGCGTACCCTGCATTTTGAAGGCC AGACGGCCATGCTTGATGCGTTGAAAACCGTGCTTGGAAAAATGCATCAGGATGCGCTGCCGCCAGAATCGGTGGATGTG TTCTGCTACAGCAAAAACTTGCGCGGCGTGATGCGTAACTTGGTTTATCAACTGTTGGCTGAGTGTATCGATTTGCGCCT CAAGCCGATGGAGCAAGAGAAACGTCGTCGTTTCAAAGCGCTGCGCATGGGCGATCAGATGTATGGTTTGTTCTTTGAAC GTCGTGGTGTTTCGGTTCAGAAGTTGGAGAACTCGGTTGATTTCTATCGCAGCATCTCAACCAATAAGCTCAAGGGCTCG CCTTTACTGATGCTCGATCGCGATCAAGATTACCCATTGCCAGCGGTGGTGGATAGTTTTGCCAGTGAAGGTTTGGTGCA GTTCTTCTTTGAAGATACCGAGAAAGGTTTCAACATCTATGTGCTTGATGAGGCCAACCGCGTTGAAGTCTATCACCAGT TTAATGGCGAAAAAGACGAAATGATTGCCAGCGTCAACAGCTTCTACACCTCGATGTTGGATGACAGCAATAAACTCGGC GCGAAAAGCATCAATTTTAACTTGCCGCAGTATTACCAAATCATCCACCCTGAAGAGGGAGAAACGTACGTGGTGCCGTA CCGTAACGACAGCGCTGTGTATTCCAAGCCTTCGCAAGTGGTCAATGCCTAA
Upstream 100 bases:
>100_bases CAAACCGGAAAGAAGTGTTAGATTGATCACGTTTTGTTGGCATGGTCGCGTAAAACATAACCAAAAAGCGGCTTTTATCT GTCATATCAGGGAAGCAAAC
Downstream 100 bases:
>100_bases CTCGTTGACGTCTCAGGTTTTCTAAATCCTTATCAATAAAAAAGAGCACAATCGTGCTCTTTTTTATTATGCGTCAGTGG CAGCATGCCTAAGCGACTTT
Product: adenylate cyclase
Products: NA
Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]
Number of amino acids: Translated: 843; Mature: 843
Protein sequence:
>843_residues MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQQQFIDDAQLT LGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFR HNHSEALSGENCGSSQHLLLLDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEE YFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEKVTRYLVRIGDSTRL DLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQF ARRNDITSAISPQDISILARKLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQP YLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQALANPCEISQLAMFINFE HDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDV FCYSKNLRGVMRNLVYQLLAECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGS PLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEMIASVNSFYTSMLDDSNKLG AKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQVVNA
Sequences:
>Translated_843_residues MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQQQFIDDAQLT LGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFR HNHSEALSGENCGSSQHLLLLDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEE YFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEKVTRYLVRIGDSTRL DLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQF ARRNDITSAISPQDISILARKLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQP YLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQALANPCEISQLAMFINFE HDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDV FCYSKNLRGVMRNLVYQLLAECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGS PLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEMIASVNSFYTSMLDDSNKLG AKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQVVNA >Mature_843_residues MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQQQFIDDAQLT LGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFR HNHSEALSGENCGSSQHLLLLDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEE YFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEKVTRYLVRIGDSTRL DLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQF ARRNDITSAISPQDISILARKLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQP YLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQALANPCEISQLAMFINFE HDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDV FCYSKNLRGVMRNLVYQLLAECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGS PLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEMIASVNSFYTSMLDDSNKLG AKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQVVNA
Specific function: Unknown
COG id: COG3072
COG function: function code F; Adenylate cyclase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the adenylyl cyclase class-1 family [H]
Homologues:
Organism=Escherichia coli, GI1790238, Length=842, Percent_Identity=54.9881235154394, Blast_Score=931, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000274 [H]
Pfam domain/function: PF01295 Adenylate_cycl [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 97349; Mature: 97349
Theoretical pI: Translated: 6.00; Mature: 6.00
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFG CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE IHLFEANPIQQQFIDDAQLTLGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVS EEEEECCCHHHHHCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEC AQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFRHNHSEALSGENCGSSQHLLL CCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHCCHHHHCCCCCCCCCCEEEH LDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEE HHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHH YFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSY HHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHH YQMLEKVTRYLVRIGDSTRLDLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQW HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC SADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQFARRNDITSAISPQDISILAR CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH KLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQP HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCC YLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPT CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH MQALANPCEISQLAMFINFEHDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYR HHHHCCCCCHHHEEEEEEECCCCCHHCCCCEEEEEECCEEEEECCCCCCEEECCCHHEEC NSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDVFCYSKNLRGVMRNLVYQLLA CCHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHH ECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGS HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC PLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDE EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCHHH MIASVNSFYTSMLDDSNKLGAKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQV HHHHHHHHHHHHHCCCCCCCCCEECCCCCHHEEEEECCCCCEEEEEECCCCCCCCCCHHH VNA CCC >Mature Secondary Structure MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFG CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE IHLFEANPIQQQFIDDAQLTLGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVS EEEEECCCHHHHHCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEC AQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFRHNHSEALSGENCGSSQHLLL CCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHCCHHHHCCCCCCCCCCEEEH LDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEE HHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHH YFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSY HHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHH YQMLEKVTRYLVRIGDSTRLDLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQW HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC SADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQFARRNDITSAISPQDISILAR CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH KLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQP HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCC YLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPT CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH MQALANPCEISQLAMFINFEHDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYR HHHHCCCCCHHHEEEEEEECCCCCHHCCCCEEEEEECCEEEEECCCCCCEEECCCHHEEC NSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDVFCYSKNLRGVMRNLVYQLLA CCHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHH ECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGS HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC PLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDE EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCHHH MIASVNSFYTSMLDDSNKLGAKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQV HHHHHHHHHHHHHCCCCCCCCCEECCCCCHHEEEEECCCCCEEEEEECCCCCCCCCCHHH VNA CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8874804; 11586360; 12142430; 8418825 [H]