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The map label for this gene is csd [H]

Identifier: 226951085

GI number: 226951085

Start: 4142425

End: 4143579

Strand: Direct

Name: csd [H]

Synonym: CLM_4138

Alternate gene names: 226951085

Gene position: 4142425-4143579 (Clockwise)

Preceding gene: 226951065

Following gene: 226951086

Centisome position: 99.69

GC content: 29.61

Gene sequence:

>1155_bases
ATGAAAGTTTATTTAGATAATGCAGCTACTACTTATCCAAAACCAGAGAAAGTTTATTCTTCTATATTAAACTATATGAA
AAATGTTGGTGCTAGCCCTGGTAGAGGTGGATATGAAAATGCTCTTACAGGAGATAGAATGGTCTATAAATGTAGGCAGT
CTTTAATAAATCTATTTAATTTTAATAAAATAGAAAATGTAGTATTTACATCTAACATTACAGCATCATTAAATATATTA
ATAAAATCCATTGTAAAGGATGGATGGCATGTAATAACTTCTTCAATGGATCATAATTCTGTAATTAGACCTTTAGTTTC
ATTAGAAAAATCAAATAAAATTGAACTAGATATATTGAATTGTTCAAAAGAAGGCTTAATAAATATTGAGGATTTTAAAA
ATACAATAAAAGATAGCACAAGACTAGTTGTACTATCTCATGCATCAAACATTGTTGGAACAATTCAACCCTTAGAAACT
ATAGGTAAGATATGTAAAGAAAAAGGAATTTATTTTATCATAGACTCTGCTCAAACTGCTGGTGTTTTACCTCTAAATTT
TCAAAATTTAAATTGTAACGCATTAGCATTTACTGGGCATAAGTCTCTACTTGGCCCTCAAGGCATAGGTGGCTTCATAA
TTGATGATGAATTGAATAATATTGCTACTAATTTTATAGAGGGTGGTACTGGTAGTCTATCTGAAAGTACATTACAACCA
GATTTTCTTCCTGATAAATTTGAAAGTGGTACTATGAATACTCCTGGAATTGCTGGACTTTTAGCTGGCATTGAATACAT
AAATGAAGAGGGTTTAAATGCTATAAAAGAAAGAGAAGAATATCTCTCAAGAGAATTTATAAATGGCCTATTAAATATAG
ACTCCGTTAAAGTTTATGGCCCTTTAGATGCATCTTTAAGAACTGCAACAATATCTATTAATTCATCAAAAATTGATAAT
TCTGAACTAGGATTTTTATTAGATAGTGAGTTTGGTATAATGGTAAGAACAGGTCTTCATTGTGCACCTTTAGCCCATAA
AACTATAGGATCATTCCCTCAAGGTACACTAAGATTTAGCTTTGGTGCATTTAATGATATTAAAGATATTAATTATGCTT
TATACGCTTTAAATAGTATACTTAACAGGATGTGA

Upstream 100 bases:

>100_bases
ATAATTATATATAAATATTTGCACAATTAATGTAATATTAAATATTATTAACAAATATTTAATATTTATTTGGATATATT
ATTCTATGGGAGGTTTTTAG

Downstream 100 bases:

>100_bases
TTTATAAAATAAAATGAATAAATTTATAGAAAAATTAGATAACCTAATATTATTTTTTATAATATATACTATTTCTTTTT
TAATATTTTTTAAAACCTTA

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKVYLDNAATTYPKPEKVYSSILNYMKNVGASPGRGGYENALTGDRMVYKCRQSLINLFNFNKIENVVFTSNITASLNIL
IKSIVKDGWHVITSSMDHNSVIRPLVSLEKSNKIELDILNCSKEGLINIEDFKNTIKDSTRLVVLSHASNIVGTIQPLET
IGKICKEKGIYFIIDSAQTAGVLPLNFQNLNCNALAFTGHKSLLGPQGIGGFIIDDELNNIATNFIEGGTGSLSESTLQP
DFLPDKFESGTMNTPGIAGLLAGIEYINEEGLNAIKEREEYLSREFINGLLNIDSVKVYGPLDASLRTATISINSSKIDN
SELGFLLDSEFGIMVRTGLHCAPLAHKTIGSFPQGTLRFSFGAFNDIKDINYALYALNSILNRM

Sequences:

>Translated_384_residues
MKVYLDNAATTYPKPEKVYSSILNYMKNVGASPGRGGYENALTGDRMVYKCRQSLINLFNFNKIENVVFTSNITASLNIL
IKSIVKDGWHVITSSMDHNSVIRPLVSLEKSNKIELDILNCSKEGLINIEDFKNTIKDSTRLVVLSHASNIVGTIQPLET
IGKICKEKGIYFIIDSAQTAGVLPLNFQNLNCNALAFTGHKSLLGPQGIGGFIIDDELNNIATNFIEGGTGSLSESTLQP
DFLPDKFESGTMNTPGIAGLLAGIEYINEEGLNAIKEREEYLSREFINGLLNIDSVKVYGPLDASLRTATISINSSKIDN
SELGFLLDSEFGIMVRTGLHCAPLAHKTIGSFPQGTLRFSFGAFNDIKDINYALYALNSILNRM
>Mature_384_residues
MKVYLDNAATTYPKPEKVYSSILNYMKNVGASPGRGGYENALTGDRMVYKCRQSLINLFNFNKIENVVFTSNITASLNIL
IKSIVKDGWHVITSSMDHNSVIRPLVSLEKSNKIELDILNCSKEGLINIEDFKNTIKDSTRLVVLSHASNIVGTIQPLET
IGKICKEKGIYFIIDSAQTAGVLPLNFQNLNCNALAFTGHKSLLGPQGIGGFIIDDELNNIATNFIEGGTGSLSESTLQP
DFLPDKFESGTMNTPGIAGLLAGIEYINEEGLNAIKEREEYLSREFINGLLNIDSVKVYGPLDASLRTATISINSSKIDN
SELGFLLDSEFGIMVRTGLHCAPLAHKTIGSFPQGTLRFSFGAFNDIKDINYALYALNSILNRM

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=294, Percent_Identity=27.2108843537415, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI156713448, Length=335, Percent_Identity=26.2686567164179, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1787970, Length=387, Percent_Identity=30.4909560723514, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI48994898, Length=400, Percent_Identity=25, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789175, Length=386, Percent_Identity=25.3886010362694, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25143064, Length=293, Percent_Identity=27.3037542662116, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533177, Length=332, Percent_Identity=26.2048192771084, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=389, Percent_Identity=24.1645244215938, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI20129463, Length=395, Percent_Identity=26.3291139240506, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42067; Mature: 42067

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYLDNAATTYPKPEKVYSSILNYMKNVGASPGRGGYENALTGDRMVYKCRQSLINLFN
CEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FNKIENVVFTSNITASLNILIKSIVKDGWHVITSSMDHNSVIRPLVSLEKSNKIELDILN
CCHHCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEEE
CSKEGLINIEDFKNTIKDSTRLVVLSHASNIVGTIQPLETIGKICKEKGIYFIIDSAQTA
CCCCCCEEHHHHHHHHCCCCEEEEEECCCCHHCCHHHHHHHHHHHHHCCCEEEEECCCCC
GVLPLNFQNLNCNALAFTGHKSLLGPQGIGGFIIDDELNNIATNFIEGGTGSLSESTLQP
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCC
DFLPDKFESGTMNTPGIAGLLAGIEYINEEGLNAIKEREEYLSREFINGLLNIDSVKVYG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PLDASLRTATISINSSKIDNSELGFLLDSEFGIMVRTGLHCAPLAHKTIGSFPQGTLRFS
CCCCCEEEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHCCCCCCEEEEE
FGAFNDIKDINYALYALNSILNRM
CCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVYLDNAATTYPKPEKVYSSILNYMKNVGASPGRGGYENALTGDRMVYKCRQSLINLFN
CEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FNKIENVVFTSNITASLNILIKSIVKDGWHVITSSMDHNSVIRPLVSLEKSNKIELDILN
CCHHCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEEE
CSKEGLINIEDFKNTIKDSTRLVVLSHASNIVGTIQPLETIGKICKEKGIYFIIDSAQTA
CCCCCCEEHHHHHHHHCCCCEEEEEECCCCHHCCHHHHHHHHHHHHHCCCEEEEECCCCC
GVLPLNFQNLNCNALAFTGHKSLLGPQGIGGFIIDDELNNIATNFIEGGTGSLSESTLQP
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCC
DFLPDKFESGTMNTPGIAGLLAGIEYINEEGLNAIKEREEYLSREFINGLLNIDSVKVYG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PLDASLRTATISINSSKIDNSELGFLLDSEFGIMVRTGLHCAPLAHKTIGSFPQGTLRFS
CCCCCEEEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHCCCCCCEEEEE
FGAFNDIKDINYALYALNSILNRM
CCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]