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The map label for this gene is aprX [H]

Identifier: 226951044

GI number: 226951044

Start: 4103224

End: 4104420

Strand: Direct

Name: aprX [H]

Synonym: CLM_4083

Alternate gene names: 226951044

Gene position: 4103224-4104420 (Clockwise)

Preceding gene: 226951043

Following gene: 226951061

Centisome position: 98.75

GC content: 27.82

Gene sequence:

>1197_bases
ATGTTTTCTTTTAAAAAAAAAATTGAGGAAACTTTAAAAATAGCAATTAAAAATAATTATTATAAAAATTATAGAGTCCT
TATTATTTGTACAAACCTTCAAAAAGATATAGAAAAAAAAGTTAAATTATATAAAGGTAAAGTACTAAAATCCATATCTT
CATGTAATTGTGTTTGTGCTTATGTATCCTCTAGAGCTATTGAGCGGCTTTTAGAATATCCTCAAGTAATATATATATGT
TTAGATCCTTATGCTTATATATGTGGAAATAGTGTATGCGCTTCTAATAATGTAACTATATCAGAAAGATACTCTCTTAC
AGGAGAAAATATTGGAATAGGTGTTGTAGATACAGGTGTCTATCCCCATACAGATTTAATTAATCCTAATAATAGAATAA
AAAGCTTTTTAGACTTAATAAATAATTATAATTATCCCTATGATGACAACGGACATGGTACCTTTGTATCTGGTATTATT
GCTGGAAATGGCACCTTATCTGATGGACTTTATAAGGGCATTTCCCCTAAAAGCCATTTATGTGTAGTCAAAGCTTTTAA
TGAATTGGGGAAAGGATTTATATCTGATATATTGTTTGGAATAGAAAACTTAATAAATGTAAAGGAAGAATTTAATATAA
AGATTATTTGCCTTCCATTTGAAGTTCCTTATATTAATTATAATGTACTAGATTTATTTTCTAAAATTTTTAACATAGCT
TTAAATAATAACATAATAATTATTGTACCTTCTGGCCATAATGGAAACAGTGAAGGTTCTATACAAGGTATAGCAACTTT
AAGATCTTGTATAACCGTAGGAGGAATAGACACTACATCATTAGAAAAAAAACCATATATTTATTCCTCTTCTGGACCTT
TCTCAAATATAGAAAAACCTGACTTAGCTGCTGCAGCCGTTAACATATGTTCCTTAAATTCTAATACAGATTATATATCT
GAAAAAATGGGGAGAAAAATATATCCAAAACCTCTTGAAGAAGCTTATACTAATTTTACTGGTACCTCTTGTGCTGCAGC
ATATGTAAGCGGAGTTTGTAGTTTATTATTTGAAAATAATCAAGAGCTTTTATTTAAAGATATACTATCCTTAATGAAAG
TGTCTTGTTCTCTTTTACCTTTTTCTAAGTGGATTCAAGGTGCTGGAATTATAGATATAAATAAACTTTTACCTTAA

Upstream 100 bases:

>100_bases
AAGTAATCAGTAATATTAACATAAATATAATTTAATATAGGAACAATTTTATAACAGTTTTACTATAATATATATGTAAG
CATTTTAATAGGAGTTTTTT

Downstream 100 bases:

>100_bases
AATATATAATAAAAAAAGAGCCTATGCTCTTTTTTTTATACATTTTTTAATGCAAACTTTATAAAGGTTTTTAATAATGT
AGATAAAAACTTATCTTTAT

Product: subtilase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MFSFKKKIEETLKIAIKNNYYKNYRVLIICTNLQKDIEKKVKLYKGKVLKSISSCNCVCAYVSSRAIERLLEYPQVIYIC
LDPYAYICGNSVCASNNVTISERYSLTGENIGIGVVDTGVYPHTDLINPNNRIKSFLDLINNYNYPYDDNGHGTFVSGII
AGNGTLSDGLYKGISPKSHLCVVKAFNELGKGFISDILFGIENLINVKEEFNIKIICLPFEVPYINYNVLDLFSKIFNIA
LNNNIIIIVPSGHNGNSEGSIQGIATLRSCITVGGIDTTSLEKKPYIYSSSGPFSNIEKPDLAAAAVNICSLNSNTDYIS
EKMGRKIYPKPLEEAYTNFTGTSCAAAYVSGVCSLLFENNQELLFKDILSLMKVSCSLLPFSKWIQGAGIIDINKLLP

Sequences:

>Translated_398_residues
MFSFKKKIEETLKIAIKNNYYKNYRVLIICTNLQKDIEKKVKLYKGKVLKSISSCNCVCAYVSSRAIERLLEYPQVIYIC
LDPYAYICGNSVCASNNVTISERYSLTGENIGIGVVDTGVYPHTDLINPNNRIKSFLDLINNYNYPYDDNGHGTFVSGII
AGNGTLSDGLYKGISPKSHLCVVKAFNELGKGFISDILFGIENLINVKEEFNIKIICLPFEVPYINYNVLDLFSKIFNIA
LNNNIIIIVPSGHNGNSEGSIQGIATLRSCITVGGIDTTSLEKKPYIYSSSGPFSNIEKPDLAAAAVNICSLNSNTDYIS
EKMGRKIYPKPLEEAYTNFTGTSCAAAYVSGVCSLLFENNQELLFKDILSLMKVSCSLLPFSKWIQGAGIIDINKLLP
>Mature_398_residues
MFSFKKKIEETLKIAIKNNYYKNYRVLIICTNLQKDIEKKVKLYKGKVLKSISSCNCVCAYVSSRAIERLLEYPQVIYIC
LDPYAYICGNSVCASNNVTISERYSLTGENIGIGVVDTGVYPHTDLINPNNRIKSFLDLINNYNYPYDDNGHGTFVSGII
AGNGTLSDGLYKGISPKSHLCVVKAFNELGKGFISDILFGIENLINVKEEFNIKIICLPFEVPYINYNVLDLFSKIFNIA
LNNNIIIIVPSGHNGNSEGSIQGIATLRSCITVGGIDTTSLEKKPYIYSSSGPFSNIEKPDLAAAAVNICSLNSNTDYIS
EKMGRKIYPKPLEEAYTNFTGTSCAAAYVSGVCSLLFENNQELLFKDILSLMKVSCSLLPFSKWIQGAGIIDINKLLP

Specific function: Displays serine protease activity. Seems to have a broad substrate specificity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 44018; Mature: 44018

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFKKKIEETLKIAIKNNYYKNYRVLIICTNLQKDIEKKVKLYKGKVLKSISSCNCVCA
CCCHHHHHHHHHHHHEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
YVSSRAIERLLEYPQVIYICLDPYAYICGNSVCASNNVTISERYSLTGENIGIGVVDTGV
HHHHHHHHHHHCCCEEEEEEECCHHHHHCCCEECCCCEEEEEEEEECCCCCEEEEEECCC
YPHTDLINPNNRIKSFLDLINNYNYPYDDNGHGTFVSGIIAGNGTLSDGLYKGISPKSHL
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCE
CVVKAFNELGKGFISDILFGIENLINVKEEFNIKIICLPFEVPYINYNVLDLFSKIFNIA
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEEEECCEECCHHHHHHHHHHHHE
LNNNIIIIVPSGHNGNSEGSIQGIATLRSCITVGGIDTTSLEKKPYIYSSSGPFSNIEKP
ECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCC
DLAAAAVNICSLNSNTDYISEKMGRKIYPKPLEEAYTNFTGTSCAAAYVSGVCSLLFENN
CHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
QELLFKDILSLMKVSCSLLPFSKWIQGAGIIDINKLLP
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCC
>Mature Secondary Structure
MFSFKKKIEETLKIAIKNNYYKNYRVLIICTNLQKDIEKKVKLYKGKVLKSISSCNCVCA
CCCHHHHHHHHHHHHEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
YVSSRAIERLLEYPQVIYICLDPYAYICGNSVCASNNVTISERYSLTGENIGIGVVDTGV
HHHHHHHHHHHCCCEEEEEEECCHHHHHCCCEECCCCEEEEEEEEECCCCCEEEEEECCC
YPHTDLINPNNRIKSFLDLINNYNYPYDDNGHGTFVSGIIAGNGTLSDGLYKGISPKSHL
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCE
CVVKAFNELGKGFISDILFGIENLINVKEEFNIKIICLPFEVPYINYNVLDLFSKIFNIA
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEEEECCEECCHHHHHHHHHHHHE
LNNNIIIIVPSGHNGNSEGSIQGIATLRSCITVGGIDTTSLEKKPYIYSSSGPFSNIEKP
ECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCC
DLAAAAVNICSLNSNTDYISEKMGRKIYPKPLEEAYTNFTGTSCAAAYVSGVCSLLFENN
CHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
QELLFKDILSLMKVSCSLLPFSKWIQGAGIIDINKLLP
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]