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The map label for this gene is sstT [H]

Identifier: 226950857

GI number: 226950857

Start: 3913804

End: 3914976

Strand: Direct

Name: sstT [H]

Synonym: CLM_3870

Alternate gene names: 226950857

Gene position: 3913804-3914976 (Clockwise)

Preceding gene: 226950820

Following gene: 226950858

Centisome position: 94.19

GC content: 32.14

Gene sequence:

>1173_bases
ATGAAAAAATTGGGGTTAATACCCAAAATTATTATAGCCATCATTTTGGGTATTCTAATAGGTAGCTTTACACCAATTCC
TGTAATACGCATATTTAGAACTTTTAGCTCCATATTTGGAGAATTTCTAGGATTCCTTATACCTTTAATAATTCTGGGAT
TCATTGTCGCTGGTATCGCTGAACTTGGACAAGGTGCTGGTAAGCTGTTAGGAATTACTGTTGGTTTAGCTTATTTATTC
ACATTAATATCTGGTTTTTCTGCTTTATTAGTTGGTAGAACATTATTGCCATCAATTATTACTAGTGCCACTCATGTAGA
AAAAGCTAAAAAAGCTCTGGATCCATTCTTTGAAGTTAAAATTCCACCAATGATGGACGTTATGACTGCACTTATATTTG
CTTTTATATTAGGGTTAGGTATTGCAAAGATACAAAATAAAACTTTAAAGGATATAGCTATAGGATTCCAAGAAATAATA
ACAAAAGTGATTGAAAATGTCGTTATACCATTACTTCCACTATATATATTAGGCATATTCGCTAACTTAGCTTATACTGG
TGAAGTATCAACTGTTTTAAAAGTATTCTGGAAAGTATTTATAATTATAATTATTTTACATTGGATTATACTAATTTTCC
AATTCTCAGTAGGTGGATCTATTGCTGGCAAAAATCCTTTTAAATCATTAAAAATCCAGATTAGAGGTTACCTTACTGCT
TTAGGAACTCAATCTTCTGCTGCAACTATTCCTATTAATATTCAATGTTCAGAGCAAATAGGAATTAGCAAAGGTATAAG
AGACTTCGTTATTCCTTTATGTGCAACTGTTCATTTATCAGGAAGTACTATTACTTTAACTATATGTGCACTATCTGTTA
TGATGTTAAACGGTATTCCAATAAGTATACCTCAGATGGCTGGATTTATAGCTATGCTAGGTGTAACTATGGTAGCTGCT
CCTGGTGTTCCTGGAGGTGCAGTAATGGCAGCTCTTGGCATACTTCAATCAATATTAGGATTTAATGAAGCTTTACTTGG
TTTAATGATTGCTTTATATATTGCTCAAGATAGTTTTGGTACTGCCTGTAACGTATCTGGTGATCAGGCTGTAGCAATGA
TTGTGGATGCTATACAAAAAAAATGGGATAAAAATCATAATAAAAATATTTAA

Upstream 100 bases:

>100_bases
ATTTACTAATATCATATATAATTTAAAAATTAATTGCATATTATTATATAATTAGTAATTGTATTAATAACTTAAATATA
TAAAAAGGGGGAGAATATCA

Downstream 100 bases:

>100_bases
CTAAACAATTTATATAAAATGGGTGTATAAAAGTTTTTACTTTTATGCACTCATTTTGTTAAAATAGGAATAATTTTAGC
CCTAAAAAATACCTTTTATA

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDIAIGFQEII
TKVIENVVIPLLPLYILGIFANLAYTGEVSTVLKVFWKVFIIIIILHWIILIFQFSVGGSIAGKNPFKSLKIQIRGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMMLNGIPISIPQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKKWDKNHNKNI

Sequences:

>Translated_390_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDIAIGFQEII
TKVIENVVIPLLPLYILGIFANLAYTGEVSTVLKVFWKVFIIIIILHWIILIFQFSVGGSIAGKNPFKSLKIQIRGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMMLNGIPISIPQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKKWDKNHNKNI
>Mature_390_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDIAIGFQEII
TKVIENVVIPLLPLYILGIFANLAYTGEVSTVLKVFWKVFIIIIILHWIILIFQFSVGGSIAGKNPFKSLKIQIRGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMMLNGIPISIPQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKKWDKNHNKNI

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=168, Percent_Identity=31.547619047619, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI169790839, Length=268, Percent_Identity=25.3731343283582, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4827012, Length=254, Percent_Identity=25.9842519685039, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI40254478, Length=172, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI66773030, Length=297, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789473, Length=268, Percent_Identity=26.1194029850746, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790514, Length=421, Percent_Identity=23.7529691211401, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983106, Length=275, Percent_Identity=24, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983099, Length=275, Percent_Identity=24, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=270, Percent_Identity=28.1481481481481, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=281, Percent_Identity=25.9786476868327, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41563; Mature: 41563

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEECCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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CEECCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA