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The map label for this gene is yrbE [H]

Identifier: 226950537

GI number: 226950537

Start: 3535754

End: 3536863

Strand: Reverse

Name: yrbE [H]

Synonym: CLM_3513

Alternate gene names: 226950537

Gene position: 3536863-3535754 (Counterclockwise)

Preceding gene: 226950538

Following gene: 226950536

Centisome position: 85.12

GC content: 30.99

Gene sequence:

>1110_bases
ATGAAAAAATTAAAATTTGCTATTGTTGGTTGTGGAAGAATTTCTTATAAACATGTAGAAGCTATAATAAATAATAAAGA
AGAAGCTGAATTAGTAGCAGTTTGTGATGTAATTGAAGAAAACGCTATAGAGAAGAAAAATGATTATATATCAAAATCAA
GCAAAGAAGCTAATGTAAATATATATACAGATTATAAGGAAATGCTAGAAAAAGAAGACATAGATGTAGTTACTATAGCT
ACAGAAAGTGGATATCATCCAGAAATAGCTATAAATTGTATGGATAAGAAAAAGCATATAATATGTGAAAAACCTATGGC
ACTATCTGTAGATGATGCAGATAGAATGATAGAATCAGCAAAGAAAAATAATGTTAAACTTTGTGTGAGCCATCAAAATA
GATTTAATAAACCTATACAACAATTAAGAAAGGCAGTAGAAGCTAATAGGTTTGGAAGATTAGTAAATGGCACTGCAAGA
ATATTGTGGAATAGAAATATGGGATACTATCATCAAGCACCATGGAGAGGAACTTGGGAACTTGATGGTGGTACCTTAAT
GAACCAATGTATACACAACATAGATTTGCTTCAATGGATGATGGGTGGAGAAATTGATACGGTTTATGCTCAGTGTGATA
CTTTTTTAAGAGATATAGAAGCAGAGGACTTTGGAGCTATAGTAATAAGATTTAAAAATGGATCTATAGGAATAGTTGAG
GGAAGTGCTTGTGTATATCCTAAAAATTTAGAAGAAACATTAAGTATATTTGGAGCAAAAGGTACGGCTTGCATAGGTGG
ACTTGCTGTTAATAAAATAGAAACTTGGAAATTTGAAGATGGAACTGAAAATGAAGAAGAAGATATATTAAAAGCTCAAG
AGGGAGATCCAGATTCAGTATACGGTTTTGGACATACTCCATTATTTAAAGATACAATAGATGCTGTAAAGGAAGATAGA
GCACCTCTAGTAAGTGGGGAAGAAGGAAAAAAAGGTATGGCAATAATATTAGCCGCTTATAAATCAAGACTTACAGGCAT
GCCAGTTAAATTCCCATTTAATAATTTTTCAACAATGGATATGATAAATGTAGAAAAAATAAATAAATAA

Upstream 100 bases:

>100_bases
TGTAAAGAATAATAGAGAAAAAATACACAAACTATAATATTTAATATTAGGATAAGTTCTTTTGGACTTATCCTAATTAA
TAAAATTTGGAGGTATAGTG

Downstream 100 bases:

>100_bases
TTTATTAAATAAAAATTAAATTTTTAAAATTACCATCAAAATATGATATTATATTATGGTGGTAATTTTAAAATTTTATT
TTAATATAGGAGTGAAAACA

Product: NAD-binding Rossmann fold family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKKLKFAIVGCGRISYKHVEAIINNKEEAELVAVCDVIEENAIEKKNDYISKSSKEANVNIYTDYKEMLEKEDIDVVTIA
TESGYHPEIAINCMDKKKHIICEKPMALSVDDADRMIESAKKNNVKLCVSHQNRFNKPIQQLRKAVEANRFGRLVNGTAR
ILWNRNMGYYHQAPWRGTWELDGGTLMNQCIHNIDLLQWMMGGEIDTVYAQCDTFLRDIEAEDFGAIVIRFKNGSIGIVE
GSACVYPKNLEETLSIFGAKGTACIGGLAVNKIETWKFEDGTENEEEDILKAQEGDPDSVYGFGHTPLFKDTIDAVKEDR
APLVSGEEGKKGMAIILAAYKSRLTGMPVKFPFNNFSTMDMINVEKINK

Sequences:

>Translated_369_residues
MKKLKFAIVGCGRISYKHVEAIINNKEEAELVAVCDVIEENAIEKKNDYISKSSKEANVNIYTDYKEMLEKEDIDVVTIA
TESGYHPEIAINCMDKKKHIICEKPMALSVDDADRMIESAKKNNVKLCVSHQNRFNKPIQQLRKAVEANRFGRLVNGTAR
ILWNRNMGYYHQAPWRGTWELDGGTLMNQCIHNIDLLQWMMGGEIDTVYAQCDTFLRDIEAEDFGAIVIRFKNGSIGIVE
GSACVYPKNLEETLSIFGAKGTACIGGLAVNKIETWKFEDGTENEEEDILKAQEGDPDSVYGFGHTPLFKDTIDAVKEDR
APLVSGEEGKKGMAIILAAYKSRLTGMPVKFPFNNFSTMDMINVEKINK
>Mature_369_residues
MKKLKFAIVGCGRISYKHVEAIINNKEEAELVAVCDVIEENAIEKKNDYISKSSKEANVNIYTDYKEMLEKEDIDVVTIA
TESGYHPEIAINCMDKKKHIICEKPMALSVDDADRMIESAKKNNVKLCVSHQNRFNKPIQQLRKAVEANRFGRLVNGTAR
ILWNRNMGYYHQAPWRGTWELDGGTLMNQCIHNIDLLQWMMGGEIDTVYAQCDTFLRDIEAEDFGAIVIRFKNGSIGIVE
GSACVYPKNLEETLSIFGAKGTACIGGLAVNKIETWKFEDGTENEEEDILKAQEGDPDSVYGFGHTPLFKDTIDAVKEDR
APLVSGEEGKKGMAIILAAYKSRLTGMPVKFPFNNFSTMDMINVEKINK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=203, Percent_Identity=29.064039408867, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082405, Length=379, Percent_Identity=24.802110817942, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41484; Mature: 41484

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKFAIVGCGRISYKHVEAIINNKEEAELVAVCDVIEENAIEKKNDYISKSSKEANVN
CCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEE
IYTDYKEMLEKEDIDVVTIATESGYHPEIAINCMDKKKHIICEKPMALSVDDADRMIESA
EEECHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCEEECCHHHHHHHHH
KKNNVKLCVSHQNRFNKPIQQLRKAVEANRFGRLVNGTARILWNRNMGYYHQAPWRGTWE
CCCCEEEEEECCHHCHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCEECCCCCEEEE
LDGGTLMNQCIHNIDLLQWMMGGEIDTVYAQCDTFLRDIEAEDFGAIVIRFKNGSIGIVE
ECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEE
GSACVYPKNLEETLSIFGAKGTACIGGLAVNKIETWKFEDGTENEEEDILKAQEGDPDSV
CCEEECCCCHHHHHHHHCCCCCCEECCEEECCEEEEECCCCCCCCHHHHHHCCCCCCCCE
YGFGHTPLFKDTIDAVKEDRAPLVSGEEGKKGMAIILAAYKSRLTGMPVKFPFNNFSTMD
EECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCEE
MINVEKINK
EEEHHCCCC
>Mature Secondary Structure
MKKLKFAIVGCGRISYKHVEAIINNKEEAELVAVCDVIEENAIEKKNDYISKSSKEANVN
CCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEE
IYTDYKEMLEKEDIDVVTIATESGYHPEIAINCMDKKKHIICEKPMALSVDDADRMIESA
EEECHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCEEECCHHHHHHHHH
KKNNVKLCVSHQNRFNKPIQQLRKAVEANRFGRLVNGTARILWNRNMGYYHQAPWRGTWE
CCCCEEEEEECCHHCHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCEECCCCCEEEE
LDGGTLMNQCIHNIDLLQWMMGGEIDTVYAQCDTFLRDIEAEDFGAIVIRFKNGSIGIVE
ECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEE
GSACVYPKNLEETLSIFGAKGTACIGGLAVNKIETWKFEDGTENEEEDILKAQEGDPDSV
CCEEECCCCHHHHHHHHCCCCCCEECCEEECCEEEEECCCCCCCCHHHHHHCCCCCCCCE
YGFGHTPLFKDTIDAVKEDRAPLVSGEEGKKGMAIILAAYKSRLTGMPVKFPFNNFSTMD
EECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCEE
MINVEKINK
EEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]