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The map label for this gene is aroC [H]

Identifier: 226950438

GI number: 226950438

Start: 3442849

End: 3443973

Strand: Reverse

Name: aroC [H]

Synonym: CLM_3412

Alternate gene names: 226950438

Gene position: 3443973-3442849 (Counterclockwise)

Preceding gene: 226950439

Following gene: 226950437

Centisome position: 82.88

GC content: 28.98

Gene sequence:

>1125_bases
ATGCTTAGATTTTTAGATGCAGGAGAATCTCATGGAAAGGCATTAACAGCTATAATAGAAGGCATACCATCAAATATTCA
TATAGATATAGATTTTATAAATGAGGAATTAAAAAGAAGACAGACTGGCTATGGTAGAGGAAAAAGAATGTCAATAGAAA
AGGACGAAGTAGAAATATGGTCCGGTGTCAGAGCTAATAAGACTACAGGGAATCCCATAACTTTAATTATTTATAATAAA
GACTATAATAATTGGAAAGATCTTATAAATAAAGAGGTAGAAGATAAAGATAAAATTTTTGTTCCTAGACCAGGTCATGG
AGATTTAGTGGGACACATTAAATATAATACAGGAGATATAAGAAATGTAATAGAGAGAACCTCAGCTAGAGAAACAGCTA
TTAGAACCGCTGTAGGTGCTATATGTAAATATATATTAAAATTGTTAGGTATAGATATAAGAAGCAAAATACAAAGCATA
GGAGAAATATTTGATGAGAATGTAGATATATATAATGATCATGTATATAAAGAAATAGAAGATAGTCCTTTAAGATGTTA
CAATAAAAAAGTAGAAAAGAACATGATAAATGAAATAGATAACTGTAAAAAAGAAGGAGATACTATAGGTGGAAGTATAT
ATATATCTATAAAAGGCATGCCAGTAGGTATAGGAAGTTATACTCAATGGGATAGAAAATTAGATGCTCTATTAAGTTAT
TCTATTATGTCTGTCCAGGGAATAAAGGTAGTAGAGTTTGGAGAAGGCTTAGATTTAAGTAAAAAAGGAAGTACCTTTAA
TGACGAAATATATTATGATGAAGATAATATAAAAAGAAAAAGCAATAACGCTGGAGGAATTGAAGCTGGAGTATCTAATG
GTGAGGATATAATAGTAAAGGCTTATATGAAACCAATACCATCTATAAAAAAACCTATAAGAACCATTAATTTAAAAGAA
AAAACAAATGTAGAAAACAGATACGAAAGATCTGATGTTTGTGGTGTTGTGCCAGCTTCTATAGTCTTAGAAAATGTATG
TGCATTTGAAATATTAAAAGAAATTTTGAATACATATCCCTGTGATGATTTCAATATGTTAAAAAAATACATGAGAGAAA
TGTAA

Upstream 100 bases:

>100_bases
AAAAATATCATTGTTTCAAATAATCTTTTAAGTATCACTAAAATACATTATTAATTTAGTGTATAATAGTTATAGTTTAA
ATTATAGGGGAAGTGATAAT

Downstream 100 bases:

>100_bases
AATTTGGAGGTTCATTTATGAATAAAGAAAGATTATTAATATTAGATAGTAATAGTTTATTAAATAGAGCTTTTTATGCA
TTACCTGATCTTATGACTGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLRFLDAGESHGKALTAIIEGIPSNIHIDIDFINEELKRRQTGYGRGKRMSIEKDEVEIWSGVRANKTTGNPITLIIYNK
DYNNWKDLINKEVEDKDKIFVPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIDIRSKIQSI
GEIFDENVDIYNDHVYKEIEDSPLRCYNKKVEKNMINEIDNCKKEGDTIGGSIYISIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKVVEFGEGLDLSKKGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKPIRTINLKE
KTNVENRYERSDVCGVVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM

Sequences:

>Translated_374_residues
MLRFLDAGESHGKALTAIIEGIPSNIHIDIDFINEELKRRQTGYGRGKRMSIEKDEVEIWSGVRANKTTGNPITLIIYNK
DYNNWKDLINKEVEDKDKIFVPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIDIRSKIQSI
GEIFDENVDIYNDHVYKEIEDSPLRCYNKKVEKNMINEIDNCKKEGDTIGGSIYISIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKVVEFGEGLDLSKKGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKPIRTINLKE
KTNVENRYERSDVCGVVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM
>Mature_374_residues
MLRFLDAGESHGKALTAIIEGIPSNIHIDIDFINEELKRRQTGYGRGKRMSIEKDEVEIWSGVRANKTTGNPITLIIYNK
DYNNWKDLINKEVEDKDKIFVPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIDIRSKIQSI
GEIFDENVDIYNDHVYKEIEDSPLRCYNKKVEKNMINEIDNCKKEGDTIGGSIYISIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKVVEFGEGLDLSKKGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKPIRTINLKE
KTNVENRYERSDVCGVVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=34.8901098901099, Blast_Score=158, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=30.5039787798408, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 42408; Mature: 42408

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLDAGESHGKALTAIIEGIPSNIHIDIDFINEELKRRQTGYGRGKRMSIEKDEVEIW
CCEECCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGVRANKTTGNPITLIIYNKDYNNWKDLINKEVEDKDKIFVPRPGHGDLVGHIKYNTGDI
CCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEECCCCCCCEEEEEEECCHHH
RNVIERTSARETAIRTAVGAICKYILKLLGIDIRSKIQSIGEIFDENVDIYNDHVYKEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
DSPLRCYNKKVEKNMINEIDNCKKEGDTIGGSIYISIKGMPVGIGSYTQWDRKLDALLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHHH
SIMSVQGIKVVEFGEGLDLSKKGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVK
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCEEEEE
AYMKPIPSIKKPIRTINLKEKTNVENRYERSDVCGVVPASIVLENVCAFEILKEILNTYP
EHHCCCCHHHHHHHEECCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
CDDFNMLKKYMREM
CCCHHHHHHHHHCC
>Mature Secondary Structure
MLRFLDAGESHGKALTAIIEGIPSNIHIDIDFINEELKRRQTGYGRGKRMSIEKDEVEIW
CCEECCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGVRANKTTGNPITLIIYNKDYNNWKDLINKEVEDKDKIFVPRPGHGDLVGHIKYNTGDI
CCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEECCCCCCCEEEEEEECCHHH
RNVIERTSARETAIRTAVGAICKYILKLLGIDIRSKIQSIGEIFDENVDIYNDHVYKEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
DSPLRCYNKKVEKNMINEIDNCKKEGDTIGGSIYISIKGMPVGIGSYTQWDRKLDALLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHHH
SIMSVQGIKVVEFGEGLDLSKKGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVK
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCEEEEE
AYMKPIPSIKKPIRTINLKEKTNVENRYERSDVCGVVPASIVLENVCAFEILKEILNTYP
EHHCCCCHHHHHHHEECCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
CDDFNMLKKYMREM
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA