Click here to switch to the map view.

The map label for this gene is prmA

Identifier: 226950383

GI number: 226950383

Start: 3383167

End: 3384105

Strand: Reverse

Name: prmA

Synonym: CLM_3352

Alternate gene names: 226950383

Gene position: 3384105-3383167 (Counterclockwise)

Preceding gene: 226950384

Following gene: 226950382

Centisome position: 81.44

GC content: 29.61

Gene sequence:

>939_bases
ATGGATAAAGAATGGTTAGAAGTTTGTATATATACAAGTAGCGAGGCTTTAGAGGCTATATCAGGAATATTATACAATAC
AGGTGTAAAGGGAGTTTCAATAGAAGATCCTAAGGATATTGAGTTTAAAAGGAAGCATCCTGGAGATTGGGATTATTTTG
ATGAAACTTTGTTAAAAGTTAAGGATACTGCTATAGTAAAGGGATATTACAAAGAAGATGATAAGTTTAATGAGTATTTA
GATTACATAAAAAAATCTGTAAGTAACTTAGATCAATTTGGAATAGATAAAGGAGAAGGTTTAGTAGAAGTTCATAAAGT
AAATGAAGAAGATTGGGAAAATAATTGGAAAAAATATTATAAACCAACTAAGGTTTCTAATAAAATAGTTATAAAGCCCA
TTTGGGAAAATTATGATAAAAAACAAGAGGAGATAATAGTAGAATTAGATCCAGGTATGGCTTTTGGCACAGGAACTCAT
GAAACCACAAGAATGTGTATAAATGCTTTAGAAAAATATATAAAAGAGGATAGAACTGTGTTTGATATAGGTTGTGGATC
TGGAATATTATCTATAGCAGCAGCAAAATTAGGAGCTAAACATGTAATAGGCGTAGATTTGGATCCAGTAGCTGTTAAAT
CCTCTAAGGAAAATATTAAATATAACAATTTAGACAATATAGAAATATTAGAAGGTAATTTAATGGAAGTTGTAGAGGGC
AGAGCTAATATAGTAGTAGCTAATATAATAGCAGATGTTATAATATTTTTAACAGAGGGTGTCAAAGCTTTTATAGAGAA
AGGCGGATACTTTATAGCTTCTGGTATAATAAATTCAAGAAAAGAGGATGTTATTAAAAAGTTAGAAGAAACAGGCTTTA
TAATAGAAGAAGTAAGAGAAGAGGGAGAATGGGCTTGTATAGTATCAAAAATAAACTAA

Upstream 100 bases:

>100_bases
TGTTAGAGAATTCTATGGAGTGATTCTTAGTTTCAGGTAGAGTTTGCTTAGAAGGAATAGTTTACTAATAGTAGTTTTTT
ATTTTAAGGAGGAATTTTTC

Downstream 100 bases:

>100_bases
AATCATTTTAATAATTTTATAAAAAGTGTATTTTTAGAATATAAAAATTTATATTTAGGACTCCCTTTATTAAAAAATGT
TAAAGTAGGTGATTATTGTG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYL
DYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTH
ETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEG
RANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVREEGEWACIVSKIN

Sequences:

>Translated_312_residues
MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYL
DYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTH
ETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEG
RANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVREEGEWACIVSKIN
>Mature_312_residues
MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYL
DYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTH
ETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEG
RANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVREEGEWACIVSKIN

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=311, Percent_Identity=31.8327974276527, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_CLOB1 (A7FXL3)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385217.1
- ProteinModelPortal:   A7FXL3
- SMR:   A7FXL3
- STRING:   A7FXL3
- GeneID:   5397973
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2921
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   CBOT441770:CLB_2921-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35338; Mature: 35338

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKV
CCHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYY
HHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHC
KPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKYIKEDRTV
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCEE
FDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEG
EEECCCCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCCCCCCCCEEEECCCHHHHHCC
RANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVRE
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHCCHHHHHHHHHHHCCHHHHHHHH
EGEWACIVSKIN
CCCEEEEEEECC
>Mature Secondary Structure
MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKV
CCHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYY
HHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHC
KPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKYIKEDRTV
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCEE
FDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEG
EEECCCCHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCCCCCCCCEEEECCCHHHHHCC
RANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVRE
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHCCHHHHHHHHHHHCCHHHHHHHH
EGEWACIVSKIN
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA